Time course of enhanced endothelium-mediated dilation in aorta of trained rats

Medicine and Science in Sports and Exercise

Volumn 29, Issue 11, 1997, Pages 1454-1461

  Delp, Michael D ^b   Laughlin, M Harold ^a  

^a UNIVERSITY OF MISSOURI   (United States)

^b NONE

Author keywords

Acetylcholine; Exercise; Indomethacin; L arginine; L name; Nitric oxide; Synthase

Indexed keywords

ACETYLCHOLINE; ARGININE; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

ABDOMINAL AORTA; ADAPTATION; ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL TONE; EXERCISE; MUSCLE METABOLISM; MUSCLE MITOCHONDRION; NONHUMAN; RAT; SKELETAL MUSCLE; SOLEUS MUSCLE; VASCULAR ENDOTHELIUM; VASCULAR RING; VASODILATATION;

NON-PROGRAMMATIC;

ACETYLCHOLINE; ANIMALS; AORTA, ABDOMINAL; ENDOTHELIUM, VASCULAR; INDOMETHACIN; MALE; MUSCLE, SKELETAL; NITRIC OXIDE SYNTHASE; PHYSICAL CONDITIONING, ANIMAL; PHYSICAL ENDURANCE; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 0030817364     PISSN: 01959131     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005768-199711000-00011     Document Type: Article

References (34)

1. ARMSTRONG, R. B., M. D. DELP, E. F. GOLJAN, and M. H. LAUGHLIN, Distribution of blood flow in muscles of miniature swine during exercise. J. Appl. Physiol. 62:1285-1298, 1987.
2. ARMSTRONG, R. B. and M. H. LAUGHLIN, Exercise blood flow patterns within and among rat muscles after training. Am. J. Physiol. 246 (Heart Circ. Physiol. 15):H59-H68, 1984.
3. BALDWIN, K. M., D. A. COOKE, and W. G. CHEADLE, Time course adaptations in cardiac and skeletal muscle to different running programs. J. Appl. Physiol: Respir. Environ. Exerc. Physiol. 42:267-272, 1977.
4. DELP, M. D. Effects of exercise training on endothelium-dependent peripheral vascular responsiveness. Med. Sci. Sports Exerc. 27:1152-1157, 1995.
5. DELP, M. D., R. M. MCALLISTER, and M. H. LAUGHLIN, Exercise training alters endothelium-dependent vasoreactivity of rat abdominal aorta. J. Appl. Physiol. 75:1354-1363, 1993.
6. DELP, M. D., R. M. MCALLISTER, and M. H. LAUGHLIN, Exercise training alters aortic vascular reactivity in hypothyroid rats. Am. J. Physiol. 268 (Heart Circ. Physiol. 37):H1428-H1435. 1995.
7. DYKE, C. K., D. N. PROCTOR, N. M. DIETZ, and M. J. JOYNER, Role of nitric oxide in exercise hyperaemia during prolonged rhythmic hand gripping in humans. J. Physiol. 488:259-265, 1995.
8. EKELUND, U. and S. MELLANDER, Role of endothelium-derived nitric oxide in the regulation of tonus in large-bore arterial resistance vessels, arterioles and veins in cat skeletal muscle. Acta Physiol. Scand. 140:301-309, 1990.
9. GILLIGAN, D. M., J. A. PANZA, C. M. KILCOYNE., M. A. WACLAWIW, P. R. CASINO, and A. A. QUYYUMI, Contribution of endothelium-derived nitric oxide to exercise-induced vasodilation. Circulation 90:2853-2858, 1994.
10. HESTER, R. L., A. ERASLAN, and Y. SAITO, Differences in EDNO contribution to arteriolar diameters at rest and during functional dilation in striated muscle. Am. J. Physiol. 265:H146-H151, 1993.
11. HIRAI, T., M. D. VISNESKI, K. J. KEARNS, R. ZELIS, and T. I. MUSCH, Effects of NO synthase inhibition on the muscular blood flow response to treadmill exercise in rats. J. Appl. Physiol. 77:1288-1293, 1994.
12. HOLLOSZY, J. O. and K. F. COYLE, Adaptations of skeletal muscle to endurance exercise and their metabolic consequences. J. Appl. Physiol. 56:831-838, 1984.
13. KALEY, G., A. KOLLER, J. M. RODENBURG, E. J. MESSINA, and M. S. WOLIN, Regulation of arteriolar tone and responses via L-arginine pathway in skeletal muscle. Am. J. Physiol. 262:H987-H992, 1992.
14. KLAUSEN, K., H. S. NIELS, J. P. CLAUSEN, O. HARTLING, and J. TRAP-JENSEN, Central and regional circulatory adaptations to one-leg training. J. Appl. Physiol. Respir. Environ. Exerc. Physiol. 52:976-983, 1982.
15. KOLLER, A. and G. KALEY, Endothelial regulation of wall shear stress and blood flow in skeletal muscle microcirculation. Am. J. Physiol. 260:H862-H868, 1991.
16. LAUGHLIN, M. H. and R. B. ARMSTRONG, Muscular blood flow distribution patterns as a function of running speed in rats. Am. J. Physiol. 243 (Heart Circ. Physiol. 12):H296-H306, 1982.
17. LAUGHLIN, M. H., R. J. KORTHUIS, D. J. DUNCKER, and R. J. BACHE, Control of blood flow to cardiac and skeletal muscle during exercise. In: Handbook of Physiology, Exercise: Regulation and Integration of Multiple Systems, L. B. Rowell and J. T. Sheperd (Ed.), Bethesda: American Physiological Society, 1996, pp. 705-769.
18. LAUGHLIN, M. H., R. J. KORTHUIS, W. L. SEXTON, and R. B. ARMSTRONG, Regional muscle blood flow capacity and exercise hyperemia in high-intensity trained rats. J. Appl. Physiol. 64:2420-2427, 1988.
19. LAUGHLIN, M. H., R. M. MCALLISTER, and M. D. DELP. Physical activity and the micro-circulation in cardiac and skeletal muscle. In: Physical Activity, Fitness, and Health: International Proceedings and Consensus Statement. C. Bouchant, R. J. Shephard, and T. Stephens (Ed.), Champaign IL: Human Kinetics Publishers, 1994. pp. 302-319.
20. LAUGHUN, M. H. and J. RIPPERGER, Vascular transport capacity of hindlimb muscles of exercise-trained rats. J. Appl. Physiol. 62:438-443, 1987.
21. LÜSCHER, T. F. and P. M. VANHOUTTE, The Endothelium: Modulator of Cardiovascular Function. Boca Raton: CRC Press, 1990, pp 23-53.
22. MACKIE, B. G. and R. L. TERJUNG, Influence of training on blood flow to different skeletal muscle fiber types. J. Appl. Physiol. 55:1072-1078, 1983.
23. MELLANDER, S. and J. BJORNBERG, Regulation of vascular smooth muscle tone and capillary pressure. NIPS 7:113-119, 1992.
24. MULLER. J. M., P. R. MYERS, and M. H. LAUGHLIN, Vasodilator responses of coronary resistance arteries of exercise-trained pigs. Circulation 89:2308-2314, 1994.
25. MUSCH, T. I., G. C. HAIDET, G. A. ORDWAY, J. C. LONGHURST, and J. H. MITCHELL Training effects on regional blood flow response to maximal exercise in foxhounds. J. Appl. Physiol. 62:1724-1732, 1987.
26. MUSCH, T. I., J. A. TERRELL, and M. R. HILTY, Effects of high-intensity sprint training on skeletal muscle blood flow in rats. J. Appl. Physiol. 71:1387-1395, 1991.
27. NADAUD, S., M. PHILIPPE, J.-F. ARNAL, J.-B. MICHEL, and F. SOU-BRIER, Sustained increase in aortic endothelial nitric oxide synthase expression in vivo in a model of chronic high blood flow. Circ. Res. 79:857-863, 1996.
28. PETTE, D. and G. VRBOVA, Adaptation of mammalian skeletal muscle fibers to chronic electrical stimulation. Rev. Physiol. Biochem. Pharmacol. 120:115-202, 1992.
29. SESSA, W. C., K. PRITCHARD, N. SEYEDI, J. WANG, and T. H. HINTZE, Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ. Res. 74:349-353, 1994.
30. SEXTON, W. L., R. J. KORTHIUS, and M. H. LAUGHLIN, High-intensity exercise training increases vascular transport capacity of rat hindquarters. Am. J. Physiol. 254 (Heart Circ. Physiol. 23):H274-H278, 1988.
31. SRERE, P. A. Citrate synthase. Methods Emymol. 13:3-5, 1969.
32. SUN, D., A. HUANG, A. KOLLER, and G. KALLEY, Short-term daily exercise activity enhances endothelial NO synthesis in skeletal muscle arterioles of rats. J. Appl. Physiol. 76:2241-2247, 1994.
33. TERIUNG, R. L. The turnover of cytochrome c in different skeletal-muscle fibre types of the rat. Biochem. J. 178:569-574, 1979.
34. VALLANCE, P., J. COLLIER, and S. MONCADA, Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man. Lancet Oct. 997-1000:1989.