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Volumn 49, Issue 3, 2013, Pages 491-500

Effects of dimethylarginine dimethylaminohydrolase-1 overexpression on the response of the pulmonary vasculature to hypoxia

Author keywords

Asymmetric dimethylarginine; Cyclic guanosine monophosphate; Hypoxia induced pulmonary hypertension; Hypoxic pulmonary vasoconstriction; Nitric oxide

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; CYCLIC GMP; DIMETHYLARGININE DIMETHYLAMINOHYDROLASE 1; HYDROLASE; N(G) NITROARGININE; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE; UNCLASSIFIED DRUG;

EID: 84883469229     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0330OC     Document Type: Article
Times cited : (15)

References (46)
  • 3
    • 0035082449 scopus 로고    scopus 로고
    • 2+-sensitising, vasoconstrictor from the perfused rat lung
    • DOI 10.1016/S0008-6363(01)00192-4, PII S0008636301001924
    • Robertson TP, Ward JP, Aaronson PI. Hypoxia induces the release of a pulmonary-selective, Ca(2+)-sensitising, vasoconstrictor from the perfused rat lung. Cardiovasc Res 2001;50:145-150. (Pubitemid 32244394)
    • (2001) Cardiovascular Research , vol.50 , Issue.1 , pp. 145-150
    • Robertson, T.P.1    Ward, J.P.T.2    Aaronson, P.I.3
  • 4
    • 0034659397 scopus 로고    scopus 로고
    • Voltage-independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat
    • Robertson TP, Hague D, Aaronson PI, Ward JP. Voltage-independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat. J Physiol 2000;525:669-680. (Pubitemid 30426788)
    • (2000) Journal of Physiology , vol.525 , Issue.3 , pp. 669-680
    • Robertson, T.P.1    Hague, D.2    Aaronson, P.I.3    Ward, J.P.T.4
  • 6
    • 79955047965 scopus 로고    scopus 로고
    • Nitric oxide signalling in the regulation of cardiovascular and platelet function
    • Gkaliagkousi E, Ferro A. Nitric oxide signalling in the regulation of cardiovascular and platelet function. Front Biosci 2011;16:1873-1897.
    • (2011) Front Biosci , vol.16 , pp. 1873-1897
    • Gkaliagkousi, E.1    Ferro, A.2
  • 8
    • 0033228518 scopus 로고    scopus 로고
    • Mechanisms of structural remodeling in chronic pulmonary hypertension
    • Durmowicz AG, Stenmark KR. Mechanisms of structural remodeling in chronic pulmonary hypertension. Pediatr Rev 1999;20:e91-e102.
    • (1999) Pediatr Rev , vol.20
    • Durmowicz, A.G.1    Stenmark, K.R.2
  • 9
    • 0035676884 scopus 로고    scopus 로고
    • Pulmonary vascular remodeling: A target for therapeutic intervention in pulmonary hypertension
    • DOI 10.1016/S0163-7258(01)00157-7, PII S0163725801001577
    • Jeffery TK, Wanstall JC. Pulmonary vascular remodeling: a target for therapeutic intervention in pulmonary hypertension. Pharmacol Ther 2001;92:1-20. (Pubitemid 34032020)
    • (2001) Pharmacology and Therapeutics , vol.92 , Issue.1 , pp. 1-20
    • Jeffery, T.K.1    Wanstall, J.C.2
  • 12
    • 0141615859 scopus 로고    scopus 로고
    • Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension
    • DOI 10.1161/01.CIR.0000089087.25930.FF
    • Millatt LJ, Whitley GS, Li D, Leiper JM, Siragy HM, Carey RM, Johns RA. Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension. Circulation 2003;108:1493-1498. (Pubitemid 37176457)
    • (2003) Circulation , vol.108 , Issue.12 , pp. 1493-1498
    • Millatt, L.J.1    Whitley, G.St.J.2    Li, D.3    Leiper, J.M.4    Siragy, H.M.5    Carey, R.M.6    Johns, R.A.7
  • 13
    • 0035085477 scopus 로고    scopus 로고
    • Plasma levels of asymmetrical dimethyl-L-arginine in patients with congenital heart disease and pulmonary hypertension
    • DOI 10.1097/00005344-200104000-00016
    • Gorenflo M, Zheng C, Werle E, Fiehn W, Ulmer HE. Plasma levels of asymmetrical dimethyl-L-arginine in patients with congenital heart disease and pulmonary hypertension. J Cardiovasc Pharmacol 2001;37:489-492. (Pubitemid 32240431)
    • (2001) Journal of Cardiovascular Pharmacology , vol.37 , Issue.4 , pp. 489-492
    • Gorenflo, M.1    Zheng, C.2    Werle, E.3    Fiehn, W.4    Ulmer, H.E.5
  • 14
    • 2942577486 scopus 로고    scopus 로고
    • Cardiovascular biology of the asymmetric dimethylarginine: dimethylarginine dimethylaminohydrolase pathway
    • DOI 10.1161/01.ATV.0000128897.54893.26
    • Vallance P, Leiper J. Cardiovascular biology of the asymmetric dimethylarginine: dimethylarginine dimethylaminohydrolase pathway. Arterioscler Thromb Vasc Biol 2004;24:1023-1030. (Pubitemid 38737826)
    • (2004) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.24 , Issue.6 , pp. 1023-1030
    • Vallance, P.1    Leiper, J.2
  • 17
    • 77952067397 scopus 로고    scopus 로고
    • Dimethylarginine dimethylaminohydrolase overexpression ameliorates atherosclerosis in apolipoprotein E-deficient mice by lowering asymmetric dimethylarginine
    • Jacobi J, Maas R, Cardounel AJ, Arend M, Pope AJ, Cordasic N, Heusinger-Ribeiro J, Atzler D, Strobel J, Schwedhelm E, et al. Dimethylarginine dimethylaminohydrolase overexpression ameliorates atherosclerosis in apolipoprotein E-deficient mice by lowering asymmetric dimethylarginine. Am J Pathol 2010;176:2559-2570.
    • (2010) Am J Pathol , vol.176 , pp. 2559-2570
    • Jacobi, J.1    Maas, R.2    Cardounel, A.J.3    Arend, M.4    Pope, A.J.5    Cordasic, N.6    Heusinger-Ribeiro, J.7    Atzler, D.8    Strobel, J.9    Schwedhelm, E.10
  • 20
    • 84867817981 scopus 로고    scopus 로고
    • Arginine-based inhibitors of nitric oxide synthase: Therapeutic potential and challenges
    • Ví teček J, Lojek A, Valacchi G, Kubala L. Arginine-based inhibitors of nitric oxide synthase: therapeutic potential and challenges. Mediators Inflamm 2012;2012:318087.
    • (2012) Mediators Inflamm , vol.2012 , pp. 318087
    • Ví Teček, J.1    Lojek, A.2    Valacchi, G.3    Kubala, L.4
  • 21
    • 46849095596 scopus 로고    scopus 로고
    • Regulation of eNOS-derived superoxide by endogenous methylarginines
    • DOI 10.1021/bi702377a
    • Druhan LJ, Forbes SP, Pope AJ, Chen CA, Zweier JL, Cardounel AJ. Regulation of eNOS-derived superoxide by endogenous methylarginines. Biochemistry 2008;47:7256-7263. (Pubitemid 351956374)
    • (2008) Biochemistry , vol.47 , Issue.27 , pp. 7256-7263
    • Druhan, L.J.1    Forbes, S.P.2    Pope, A.J.3    Chen, C.-A.4    Zweier, J.L.5    Cardounel, A.J.6
  • 22
    • 0029938767 scopus 로고    scopus 로고
    • Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclase
    • Schrammel A, Behrends S, Schmidt K, Koesling D, Mayer B. Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclase. Mol Pharmacol 1996;50:1-5. (Pubitemid 26250067)
    • (1996) Molecular Pharmacology , vol.50 , Issue.1 , pp. 1-5
    • Schrammel, A.1    Behrends, S.2    Schmidt, K.3    Koesling, D.4    Mayer, B.5
  • 23
    • 0033601250 scopus 로고    scopus 로고
    • Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase
    • Feng J, Ito M, Ichikawa K, Isaka N, Nishikawa M, Hartshorne DJ, Nakano T. Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase. J Biol Chem 1999;274:37385-37390.
    • (1999) J Biol Chem , vol.274 , pp. 37385-37390
    • Feng, J.1    Ito, M.2    Ichikawa, K.3    Isaka, N.4    Nishikawa, M.5    Hartshorne, D.J.6    Nakano, T.7
  • 24
    • 0037158625 scopus 로고    scopus 로고
    • Endothelium-derived mediators and hypoxic pulmonary vasoconstriction
    • DOI 10.1016/S1569-9048(02)00053-8, PII S1569904802000538
    • Aaronson PI, Robertson TP, Ward JP. Endothelium-derived mediators and hypoxic pulmonary vasoconstriction. Respir Physiol Neurobiol 2002;132:107-120. (Pubitemid 34765693)
    • (2002) Respiratory Physiology and Neurobiology , vol.132 , Issue.1 , pp. 107-120
    • Aaronson, P.I.1    Robertson, T.P.2    Ward, J.P.T.3
  • 28
    • 77958050374 scopus 로고    scopus 로고
    • Roles for soluble guanylate cyclase and a thiol oxidation-elicited subunit dimerization of protein kinase G in pulmonary artery relaxation to hydrogen peroxide
    • Neo BH, Kandhi S, Wolin MS. Roles for soluble guanylate cyclase and a thiol oxidation-elicited subunit dimerization of protein kinase G in pulmonary artery relaxation to hydrogen peroxide. Am J Physiol Heart Circ Physiol 2010;299:H1235-H1241.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299
    • Neo, B.H.1    Kandhi, S.2    Wolin, M.S.3
  • 29
  • 30
    • 84877805609 scopus 로고    scopus 로고
    • Mechanism of cellular oxidation stress induced by asymmetric dimethylarginine
    • Mohan S, Fung HL. Mechanism of cellular oxidation stress induced by asymmetric dimethylarginine. Int J Mol Sci 2012;13:7521-7531.
    • (2012) Int J Mol Sci , vol.13 , pp. 7521-7531
    • Mohan, S.1    Fung, H.L.2
  • 33
    • 33745965542 scopus 로고    scopus 로고
    • New tricks from an old dog: Nitric oxide-independent effects of dimethylarginine dimethylaminohydrolase
    • DOI 10.1161/01.ATV.0000229598.55602.17, PII 0004360520060700000003
    • Leiper J, Vallance P. New tricks from an old dog: nitric oxide-independent effects of dimethylarginine dimethylaminohydrolase. Arterioscler Thromb Vasc Biol 2006;26:1419-1420. (Pubitemid 44288963)
    • (2006) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.26 , Issue.7 , pp. 1419-1420
    • Leiper, J.1    Vallance, P.2
  • 34
    • 72149111666 scopus 로고    scopus 로고
    • Role of dimethylarginine dimethylaminohydrolases in the regulation of endothelial nitric oxide production
    • Pope AJ, Karrupiah K, Kearns PN, Xia Y, Cardounel AJ. Role of dimethylarginine dimethylaminohydrolases in the regulation of endothelial nitric oxide production. J Biol Chem 2009;284:35338-35347.
    • (2009) J Biol Chem , vol.284 , pp. 35338-35347
    • Pope, A.J.1    Karrupiah, K.2    Kearns, P.N.3    Xia, Y.4    Cardounel, A.J.5
  • 35
    • 47249137061 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine inhibits HSP90 activity in pulmonary arterial endothelial cells: Role of mitochondrial dysfunction
    • Sud N, Wells SM, Sharma S, Wiseman DA, Wilham J, Black SM. Asymmetric dimethylarginine inhibits HSP90 activity in pulmonary arterial endothelial cells: role of mitochondrial dysfunction. Am J Physiol Cell Physiol 2008;294:C1407-C1418.
    • (2008) Am J Physiol Cell Physiol , vol.294
    • Sud, N.1    Wells, S.M.2    Sharma, S.3    Wiseman, D.A.4    Wilham, J.5    Black, S.M.6
  • 36
    • 0028987599 scopus 로고
    • Acute hypoxic vasoconstriction in isolated rat small and large pulmonary arteries
    • Zhang F, Woodmansey PA, Morice AH. Acute hypoxic vasoconstriction in isolated rat small and large pulmonary arteries. Physiol Res 1995;44:7-18.
    • (1995) Physiol Res , vol.44 , pp. 7-18
    • Zhang, F.1    Woodmansey, P.A.2    Morice, A.H.3
  • 41
    • 38049132717 scopus 로고    scopus 로고
    • Sildenafil in hypoxic pulmonary hypertension potentiates a compensatory up-regulation of NO-cGMP signaling
    • Kirsch M, Kemp-Harper B, Weissmann N, Grimminger F, Schmidt HH. Sildenafil in hypoxic pulmonary hypertension potentiates a compensatory up-regulation of NO-cGMP signaling. FASEB J 2008;22:30-40.
    • (2008) FASEB J , vol.22 , pp. 30-40
    • Kirsch, M.1    Kemp-Harper, B.2    Weissmann, N.3    Grimminger, F.4    Schmidt, H.H.5
  • 43
    • 34547627296 scopus 로고    scopus 로고
    • The effects of hypoxia on-the cells of the pulmonary vasculature
    • DOI 10.1183/09031936.00128706
    • Pak O, Aldashev A, Welsh D, Peacock A. The effects of hypoxia on the cells of the pulmonary vasculature. Eur Respir J 2007;30:364-372. (Pubitemid 47201724)
    • (2007) European Respiratory Journal , vol.30 , Issue.2 , pp. 364-372
    • Pak, O.1    Aldashev, A.2    Welsh, D.3    Peacock, A.4
  • 44
    • 0035130107 scopus 로고    scopus 로고
    • Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension
    • DOI 10.1096/fj.00-0343com
    • Taraseviciene-Stewart L, Kasahara Y, Alger L, Hirth P, Mc Mahon G, Waltenberger J, Voelkel NF, Tuder RM. Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. FASEB J 2001;15:427-438. (Pubitemid 32141434)
    • (2001) FASEB Journal , vol.15 , Issue.2 , pp. 427-438
    • Taraseviciene-Stewart, L.1    Kasahara, Y.2    Alger, L.3    Hirth, P.4    Mc, M.G.5    Waltenberger, J.6    Voelkel, N.F.7    Tuder, R.M.8
  • 45
    • 0027370627 scopus 로고
    • Acute and prolonged hypoxia attenuate endothelial nitric oxide production in rat pulmonary arteries by different mechanisms
    • Shaul PW, Wells LB, Horning KM. Acute and prolonged hypoxia attenuate endothelial nitric oxide production in rat pulmonary arteries by different mechanisms. J Cardiovasc Pharmacol 1993;22:819-827. (Pubitemid 23360403)
    • (1993) Journal of Cardiovascular Pharmacology , vol.22 , Issue.6 , pp. 819-827
    • Shaul, P.W.1    Wells, L.B.2    Horning, K.M.3


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