Effective pulmonary delivery of an aerosolized plasmid DNA vaccine via surface acoustic wave nebulization

Respiratory Research

Volumn 15, Issue 1, 2014, Pages

  Rajapaksa, Anushi E ^a,e   Ho, Jenny J ^a   Qi, Aisha ^b,c   Bischof, Rob ^a   Nguyen, Tri Hung ^a   Tate, Michelle ^a   Piedrafita, David ^a   McIntosh, Michelle P ^a   Yeo, Leslie Y ^b   Meeusen, Els ^d   Coppel, Ross L ^a   Friend, James R ^b,c  

^a MONASH UNIVERSITY   (Australia)

^b RMIT UNIVERSITY   (Australia)

^c MELBOURNE CENTRE FOR NANOFABRICATION   (Australia)

^d Department of Physiology School of Biomedical Sciences   (Australia)

^e MURDOCH CHILDREN'S RESEARCH INSTITUTE   (Australia)

Author keywords

Gene therapy; Nebulization; Surface acoustic wave

Indexed keywords

DNA VACCINE; GLYCOPROTEIN; HEMAGGLUTININ; INFLUENZA VACCINE; PLASMID DNA; PVR1020 PYMSP4 5; PVR1020 YFP; UNCLASSIFIED DRUG;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; CELLS; CONTROLLED STUDY; DNA IMMUNIZATION; DRUG DELIVERY SYSTEM; EPITHELIUM CELL; FEMALE; FILTER; GENE EXPRESSION; GENE TARGETING; IMMUNIZATION; IN VITRO STUDY; IN VIVO GENE TRANSFER; INFLUENZA; INFLUENZA A; INFLUENZA VIRUS A; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; MALE; MECHANICAL VENTILATOR; MOUSE; NEBULIZATION; NEBULIZER; NONHUMAN; PROTEIN EXPRESSION; RAT; SHEEP; SURFACE ACOUSTIC WAVE NEBULIZATION; VACCINATION; VACCINE PRODUCTION; VENTILATOR; ANIMAL; GENE TRANSFER; GENETICS; HUMAN; INHALATIONAL DRUG ADMINISTRATION; LUNG; METHODOLOGY; PHYSIOLOGY; SOUND; SPRAGUE DAWLEY RAT; SURFACE PROPERTY; TREATMENT OUTCOME;

ADMINISTRATION, INHALATION; AEROSOLS; ANIMALS; FEMALE; GENE TRANSFER TECHNIQUES; HUMANS; LUNG; MALE; MICE; NEBULIZERS AND VAPORIZERS; RATS; RATS, SPRAGUE-DAWLEY; SHEEP; SOUND; SURFACE PROPERTIES; TREATMENT OUTCOME; VACCINATION; VACCINES, DNA;

EID: 84901692006     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-15-60     Document Type: Article

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