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Volumn 197, Issue 1-2, 2000, Pages 221-231

Physical stability and in-vitro gene expression efficiency of nebulised lipid-peptide-DNA complexes

Author keywords

Aerosolisation; Cationic lipid; Gene therapy; Lung; Nebulisation; Plasmid DNA; Polycationic peptide; Protamine

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; CATIONIC SURFACTANT; PLASMID DNA; PROTAMINE; UNCLASSIFIED DRUG;

EID: 0034003204     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00339-2     Document Type: Article
Times cited : (67)

References (33)
  • 1
    • 0032014162 scopus 로고    scopus 로고
    • Towards gene therapy for cystic fibrosis: A clinical progress report
    • Alton E.W.F.W., Geddes D.M., Gill D.R. et al. Towards gene therapy for cystic fibrosis: a clinical progress report. Gene Ther. 5:1998;291-292.
    • (1998) Gene Ther. , vol.5 , pp. 291-292
    • Alton, E.W.F.W.1    Geddes, D.M.2    Gill, D.R.3
  • 2
    • 0031543510 scopus 로고    scopus 로고
    • Maintenance of transfection rates and physical characterization of lipid/DNA complexes after freeze-drying and rehydration
    • Anchordoquy T.J., Carpenter J.F., Kroll D.J. Maintenance of transfection rates and physical characterization of lipid/DNA complexes after freeze-drying and rehydration. Arch. Biochem. Biophys. 348:1997;199-206.
    • (1997) Arch. Biochem. Biophys. , vol.348 , pp. 199-206
    • Anchordoquy, T.J.1    Carpenter, J.F.2    Kroll, D.J.3
  • 3
    • 0033066932 scopus 로고    scopus 로고
    • Physico-chemical characterisation of cationic lipid:plasmid DNA gene delivery complexes
    • Birchall, J.C., Kellaway, I.W., Mills, S.N. 1999. Physico-chemical characterisation of cationic lipid:plasmid DNA gene delivery complexes. Int J Pharm 183, 195-207.
    • (1999) Int J Pharm , vol.183 , pp. 195-207
    • Birchall, J.C.1    Kellaway, I.W.2    Mills, S.N.3
  • 4
    • 0030905861 scopus 로고    scopus 로고
    • Propellant driven aerosols of DNA plasmids for gene expression in the respiratory tract
    • Brown A.R., Chowdhury S.I. Propellant driven aerosols of DNA plasmids for gene expression in the respiratory tract. J. Aerosol. Med. 10:1997;129-146.
    • (1997) J. Aerosol. Med. , vol.10 , pp. 129-146
    • Brown, A.R.1    Chowdhury, S.I.2
  • 5
    • 0028056371 scopus 로고
    • Aerosol and intravenous transfection of human alpha 1 antitrypsin gene to lungs of rabbits
    • Canonico A.E., Conary J.T., Meyrick B., Brigham K.L. Aerosol and intravenous transfection of human alpha 1 antitrypsin gene to lungs of rabbits. Am. J. Respir. Cell Mol. Biol. 10:1994;249-255.
    • (1994) Am. J. Respir. Cell Mol. Biol. , vol.10 , pp. 249-255
    • Canonico, A.E.1    Conary, J.T.2    Meyrick, B.3    Brigham, K.L.4
  • 6
    • 0029843122 scopus 로고    scopus 로고
    • Cationic liposome plasmid DNA complexes: In vitro cell entry and transgene expression augmented by synthetic signal peptides
    • Conary J.T., Erdos G., McGuire M. et al. Cationic liposome plasmid DNA complexes: In vitro cell entry and transgene expression augmented by synthetic signal peptides. Eur. J. Pharm. Biopharm. 42:1996;277-285.
    • (1996) Eur. J. Pharm. Biopharm. , vol.42 , pp. 277-285
    • Conary, J.T.1    Erdos, G.2    McGuire, M.3
  • 7
    • 0028269736 scopus 로고
    • Protection of rabbit lungs from endotoxin injury by in vivo hyperexpression of the prostaglandin G/H synthase gene
    • Conary J.T., Parker R.E., Christman B.W. et al. Protection of rabbit lungs from endotoxin injury by in vivo hyperexpression of the prostaglandin G/H synthase gene. J. Clin. Invest. 93:1994;1834-1840.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1834-1840
    • Conary, J.T.1    Parker, R.E.2    Christman, B.W.3
  • 8
    • 0029815814 scopus 로고    scopus 로고
    • Plasmid DNA molecules complexed with cationic liposomes are protected from degradation by nucleases and shearing by aerosolisation
    • Crook K., McLachlan G., Stevenson B.J., Porteus D.J. Plasmid DNA molecules complexed with cationic liposomes are protected from degradation by nucleases and shearing by aerosolisation. Gene Ther. 3:1996;834-839.
    • (1996) Gene Ther. , vol.3 , pp. 834-839
    • Crook, K.1    McLachlan, G.2    Stevenson, B.J.3    Porteus, D.J.4
  • 10
    • 0031976062 scopus 로고    scopus 로고
    • Aerosolization of cationic lipid:pDNA complexes - In vitro optimization of nebulizer parameters for human clinical studies
    • Eastman S.J., Tousignant J.D., Lukason M.J., Chu Q., Cheng S.H., Scheule R.K. Aerosolization of cationic lipid:pDNA complexes - in vitro optimization of nebulizer parameters for human clinical studies. Hum. Gene Ther. 9:1998;43-52.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 43-52
    • Eastman, S.J.1    Tousignant, J.D.2    Lukason, M.J.3    Chu, Q.4    Cheng, S.H.5    Scheule, R.K.6
  • 11
    • 0030754344 scopus 로고    scopus 로고
    • Optimisation of formulations and conditions for the aerosol delivery of functional cationic lipid:DNA complexes
    • Eastman S.J., Tousignant J.D., Lukason M.J. et al. Optimisation of formulations and conditions for the aerosol delivery of functional cationic lipid:DNA complexes. Hum. Gene Ther. 8:1997;313-322.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 313-322
    • Eastman, S.J.1    Tousignant, J.D.2    Lukason, M.J.3
  • 12
    • 0030038942 scopus 로고    scopus 로고
    • Potentiation of liposome-mediated gene delivery by polycations
    • Gao X., Huang L. Potentiation of liposome-mediated gene delivery by polycations. Biochemistry. 35:1996;1027-1036.
    • (1996) Biochemistry , vol.35 , pp. 1027-1036
    • Gao, X.1    Huang, L.2
  • 15
    • 0011581018 scopus 로고    scopus 로고
    • A novel approach for gene delivery to the lung using artificial viral envelopes as a dry powder aerosol
    • Abstract 1196
    • Holzner, P., Sorgi, F.L., Hickey, A.J., Schreier, H. 1997. A novel approach for gene delivery to the lung using artificial viral envelopes as a dry powder aerosol. Pharm Res 14 (Suppl.), S-62 Abstract 1196.
    • (1997) Pharm Res , vol.14 , Issue.SUPPL.
    • Holzner, P.1    Sorgi, F.L.2    Hickey, A.J.3    Schreier, H.4
  • 16
    • 0024597585 scopus 로고
    • Increased expression of DNA co-introduced with nuclear protein in adult rat liver
    • Kaneda Y., Iwai K., Uchida T. Increased expression of DNA co-introduced with nuclear protein in adult rat liver. Science. 243:1989;375-378.
    • (1989) Science , vol.243 , pp. 375-378
    • Kaneda, Y.1    Iwai, K.2    Uchida, T.3
  • 17
    • 19244363903 scopus 로고    scopus 로고
    • Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung
    • Lee E.R., Marshall J., Siegal C.S. et al. Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung. Hum. Gene Ther. 7:1996;1701-1717.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 1701-1717
    • Lee, E.R.1    Marshall, J.2    Siegal, C.S.3
  • 18
    • 0030866645 scopus 로고    scopus 로고
    • In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes
    • Li S., Huang L. In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes. Gene Ther. 4:1997;891-900.
    • (1997) Gene Ther. , vol.4 , pp. 891-900
    • Li, S.1    Huang, L.2
  • 19
    • 0030792222 scopus 로고    scopus 로고
    • Development of targeted delivery systems for nucleic acid drugs
    • Mahato R.I., Takakura Y., Hashida M. Development of targeted delivery systems for nucleic acid drugs. J. Drug Targeting. 4:1997;337-357.
    • (1997) J. Drug Targeting , vol.4 , pp. 337-357
    • Mahato, R.I.1    Takakura, Y.2    Hashida, M.3
  • 21
    • 0028199067 scopus 로고
    • The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems
    • Plank C., Oberhauser B., Mechtler K., Koch C., Wagner E. The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. J. Biol. Chem. 269:1994;12918-12924.
    • (1994) J. Biol. Chem. , vol.269 , pp. 12918-12924
    • Plank, C.1    Oberhauser, B.2    Mechtler, K.3    Koch, C.4    Wagner, E.5
  • 22
    • 8244245761 scopus 로고    scopus 로고
    • Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
    • Porteous D.J., Dorin J.R., McLachlan G. et al. Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Gene Ther. 4:1997;210-218.
    • (1997) Gene Ther. , vol.4 , pp. 210-218
    • Porteous, D.J.1    Dorin, J.R.2    McLachlan, G.3
  • 23
    • 0032580453 scopus 로고    scopus 로고
    • Polycation-DNA complexes for gene delivery: A comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids
    • Pouton C.W., Lucas P., Thomas B.J., Uduehi A.N., Milroy D.A., Moss S.H. Polycation-DNA complexes for gene delivery: a comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids. J. Control. Rel. 53:1998;289-299.
    • (1998) J. Control. Rel. , vol.53 , pp. 289-299
    • Pouton, C.W.1    Lucas, P.2    Thomas, B.J.3    Uduehi, A.N.4    Milroy, D.A.5    Moss, S.H.6
  • 24
  • 25
    • 0031970246 scopus 로고    scopus 로고
    • From genes to gene medicines: Recent advances in nonviral gene delivery
    • Rolland A.P. From genes to gene medicines: recent advances in nonviral gene delivery. Crit. Rev. Ther. Drug Carrier Syst. 15:1998;143-198.
    • (1998) Crit. Rev. Ther. Drug Carrier Syst. , vol.15 , pp. 143-198
    • Rolland, A.P.1
  • 26
    • 16944364834 scopus 로고    scopus 로고
    • Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to mammalian lung
    • Scheule R.K., St George J.A., Bagley R.G. et al. Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to mammalian lung. Hum. Gene Ther. 8:1997;689-707.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 689-707
    • Scheule, R.K.1    St George, J.A.2    Bagley, R.G.3
  • 27
    • 0032473415 scopus 로고    scopus 로고
    • Airway delivery of cationic lipid:DNA complexes for cystic fibrosis
    • Sheng S.H., Scheule R.K. Airway delivery of cationic lipid:DNA complexes for cystic fibrosis. Adv. Drug Delivery Rev. 30:1998;173-184.
    • (1998) Adv. Drug Delivery Rev. , vol.30 , pp. 173-184
    • Sheng, S.H.1    Scheule, R.K.2
  • 28
    • 0031558239 scopus 로고    scopus 로고
    • Toward development of a non-viral gene therapeutic
    • Smith J., Zhang Y., Niven R. Toward development of a non-viral gene therapeutic. Adv. Drug Delivery Rev. 26:1997;135-150.
    • (1997) Adv. Drug Delivery Rev. , vol.26 , pp. 135-150
    • Smith, J.1    Zhang, Y.2    Niven, R.3
  • 30
    • 0030866647 scopus 로고    scopus 로고
    • Protamine sulfate enhances lipid-mediated gene transfer
    • Sorgi F.L., Bhattacharya S., Huang L. Protamine sulfate enhances lipid-mediated gene transfer. Gene Ther. 4:1997;961-968.
    • (1997) Gene Ther. , vol.4 , pp. 961-968
    • Sorgi, F.L.1    Bhattacharya, S.2    Huang, L.3
  • 31
    • 7144256249 scopus 로고    scopus 로고
    • The effects of jet nebulisation on cationic liposome-mediated gene transfer in vitro
    • Stern M., Sorgi F., Hughes C. et al. The effects of jet nebulisation on cationic liposome-mediated gene transfer in vitro. Gene Ther. 5:1998;583-593.
    • (1998) Gene Ther. , vol.5 , pp. 583-593
    • Stern, M.1    Sorgi, F.2    Hughes, C.3
  • 32
    • 0030002508 scopus 로고    scopus 로고
    • Controllable gene therapy. Pharmaceutics of non-viral gene delivery systems
    • Tomlinson E., Rolland A.P. Controllable gene therapy. Pharmaceutics of non-viral gene delivery systems. J. Control. Rel. 39:1996;357-372.
    • (1996) J. Control. Rel. , vol.39 , pp. 357-372
    • Tomlinson, E.1    Rolland, A.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.