The Downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 Axis and by Human Cytomegalovirus (HCMV) Associated Factors Allows the Activation of the HCMV Major IE Promoter and the Transition to Productive Infection

PLoS Pathogens

Volumn 10, Issue 5, 2014, Pages

  Sourvinos, George ^a,b   Morou, Antigoni ^b   Sanidas, Ioannis ^a   Codruta, Ignea ^b   Ezell, Scott A ^a   Doxaki, Christina ^b   Kampranis, Sotirios C ^a,b   Kottakis, Filippos ^a   Tsichlis, Philip N ^a  

^a TUFTS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CRETE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; EZH2 PROTEIN, HUMAN; F BOX PROTEIN; GFI1 PROTEIN, HUMAN; HISTONE DEMETHYLASE; IMMEDIATE EARLY PROTEIN; IMMEDIATE-EARLY PROTEINS, CYTOMEGALOVIRUS; JARID2 PROTEIN, HUMAN; KDM2B PROTEIN, MOUSE; POLYCOMB REPRESSIVE COMPLEX 2; TRANSCRIPTION FACTOR; VIRUS ANTIGEN; VIRUS PROTEIN;

CELL CULTURE; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DOWN REGULATION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HUMAN; METABOLISM; PHYSIOLOGY; PROMOTER REGION; SIGNAL TRANSDUCTION; VIROLOGY; VIRUS REPLICATION;

ANTIGENS, VIRAL; CELLS, CULTURED; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DNA-BINDING PROTEINS; DOWN-REGULATION; F-BOX PROTEINS; HEK293 CELLS; HELA CELLS; HUMANS; IMMEDIATE-EARLY PROTEINS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; POLYCOMB REPRESSIVE COMPLEX 2; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84901687995     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004136     Document Type: Article

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