Host defenses in the skin

Clinical Immunology: Principles and Practice: Fourth Edition

Volumn , Issue , 2013, Pages 228-238

  Xu, Hui ^a   Timares, Laura ^b   Elmets, Craig A ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84901687663     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-7234-3691-1.00039-8     Document Type: Chapter

References (50)

1. Chu D.H., et al. The structure and development of skin. Fitzpatrick's dermatology in general medicine 2003, McGraw-Hill, New York. I.M. Freedberg (Ed.).
2. Amagai M. Pemphigus. Dermatology 2008, 417-429. Mosby/Elsevier, St. Louis. J. Bolognia, J.L. Jorizzo, R.P. Rapini (Eds.).
3. Kupper T.S., Fuhlbrigge R.C. Immune surveillance in the skin: mechanisms and clinical consequences. Nat Rev Immunol 2004, 4(3):211-222.
4. Yancey K.B., Allen D.M. The biology of the basement membrane zone. Dermatology 2008, 403-415. Mosby/Elsevier, St. Louis. J. Bolognia, J.L. Jorizzo, R.P. Rapini (Eds.).
5. Streilein J.W. Lymphocyte traffic, T-cell malignancies and the skin. J Invest Dermatol 1978, 71(3):167-171.
6. McInturff J.E., Modlin R.L., Kim J. The role of toll-like receptors in the pathogenesis and treatment of dermatological disease. J Invest Dermatol 2005, 125(1):1-8.
7. Nestle F.O., Di Meglio P., Qin J.Z., Nickoloff B.J. Skin immune sentinels in health and disease. Nat Rev Immunol 2009, 9(10):679-691.
8. Kadowaki N., Ho S., Antonenko S., et al. Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J Exp Med 2001, 194(6):863-869.
9. Watanabe H., Gaide O., Pétrilli V., et al. Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity. J Invest Dermatol 2007, 127(8):1956-1963.
10. Grossberg A.L., Gaspari A.A. Topical antineoplastic agents in the treatment of mucocutaneous diseases. Curr Probl Dermatol 2011, 40:71-82.
11. Ferwerda B., Ferwerda G., Plantinga T.S., et al. Human dectin-1 deficiency and mucocutaneous fungal infections. N Engl J Med 2009, 361(18):1760-1767.
12. Glocker E.O., Hennigs A., Nabavi M., et al. A homozygous CARD9 mutation in a family with susceptibility to fungal infections. N Engl J Med 2009, 361(18):1727-1735.
13. Steinhoff M., Brzoska T., Luger T.A. Keratinocytes in epidermal immune responses. Curr Opin Allergy Clin Immunol 2001, 1:469-487.
14. Aksentijevich I., Masters S.L., Ferguson P.J., et al. An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N Engl J Med 2009, 360(23):2426-2437.
15. Zaba L.C., Krueger J.G., Lowes M.A. Resident and "inflammatory" dendritic cells in human skin. J Invest Dermatol 2009, 129(2):302-308.
16. Schauber J., Gallo R.L. Antimicrobial peptides and the skin immune defense system. J Allergy Clin Immunol 2008, 122(2):261-266.
17. Kubo A., Nagao K., Yokouchi M., et al. External antigen uptake by Langerhans cells with reorganization of epidermal tight junction barriers. J Exp Med 2009, 206(13):2937-2946.
18. Allan R.S., Smith C.M., Belz G.T., et al. Epidermal viral immunity induced by CD8alpha+ dendritic cells but not by Langerhans cells. Science 2003, 301(5641):1925-1928.
19. Loser K., Mehling A., Loeser S., et al. Epidermal RANKL controls regulatory T-cell numbers via activation of dendritic cells. Nat Med 2006, 12(12):1372-1379.
20. Igyarto B.Z., Haley K., Ortner D., et al. Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses. Immunity 2011, 35(2):260-272.
21. Nagao K., Ginhoux F., Leitner W.W., et al. Murine epidermal Langerhans cells and langerin-expressing dermal dendritic cells are unrelated and exhibit distinct functions. Proc Natl Acad Sci U S A 2009, 106(9):3312-3317.
22. Henri S., Guilliams M., Poulin L.F., et al. Disentangling the complexity of the skin dendritic cell network. Immunol Cell Biol 2010, 88(4):366-375.
23. Clark R.A. Skin-resident T cells: the ups and downs of on site immunity. J Invest Dermatol 2010, 130(2):362-370.
24. Fujita H., Nograles K.E., Kikuchi T., et al. Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production. Proc Natl Acad Sci U S A 2009, 106(51):21795-21800.
25. He D., Wu L., Kim H.K., et al. CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses. J Immunol 2006, 177(10):6852-6858.
26. Schroder K., Hertzog P.J., Ravasi T., Hume D.A. Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol 2004, 75(2):163-189.
27. Leung D.Y., Boguniewicz M. Advances in allergic skin diseases. J Allergy Clin Immunol 2003, 111(Suppl. 3):S805-812.
28. Iwakura Y., et al. Functional specialization of interleukin-17 family members. Immunity 2011, 34(2):149-162.
29. Sakaguchi S., Yamaguchi T., Nomura T., Ono M. Regulatory T cells and immune tolerance. Cell 2008, 133(5):775-787.
30. Dudda J.C., Perdue N., Bachtanian E., Campbell D.J. Foxp3+ regulatory T cells maintain immune homeostasis in the skin. J Exp Med 2008, 205(7):1559-1565.
31. Dubois B., Chapat L., Goubier A., et al. Innate CD4+CD25+ regulatory T cells are required for oral tolerance and inhibition of CD8+ T cells mediating skin inflammation. Blood 2003, 102(9):3295-3301.
32. Krutmann J., Elmets C.A. Photoimmunology 1995, xii. Blackwell Science, Oxford/Cambridge, MA, 303.
33. Elmets C.A., Bergstresser P.R., Tigelaar R.E., et al. Analysis of the mechanism of unresponsiveness produced by haptens painted on skin exposed to low dose ultraviolet radiation. J Exp Med 1983, 158(3):781-794.
34. Yusuf N., Nasti T.H., Katiyar S.K., et al. Antagonistic roles of CD4+ and CD8+ T-cells in 7,12-dimethylbenz(a)anthracene cutaneous carcinogenesis. Cancer Res 2008, 68(10):3924-3930.
35. Finn O.J. Cancer immunology. N Engl J Med 2008, 358(25):2704-2715.
36. Kaporis H.G., Guttman-Yassky E., Lowes M.A., et al. Human basal cell carcinoma is associated with Foxp3+ T cells in a Th2 dominant microenvironment. J Invest Dermatol 2007, 127(10):2391-2398.
37. Clark R.A., Huang S.J., Murphy G.F., et al. Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells. J Exp Med 2008, 205(10):2221-2234.
38. He D., Li H., Yusef N., et al. IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells. J Immunol 2010, 184(5):2281-2288.
39. He D., Wu L., Kim H.K., et al. IL-17 and IFN-gamma mediate the elicitation of contact hypersensitivity responses by different mechanisms and both are required for optimal responses. J Immunol 2009, 183(2):1463-1470.
40. Kehren J., Desvignes C., Krasteva M., et al. Cytotoxicity is mandatory for CD8(+) T cell-mediated contact hypersensitivity. J Exp Med 1999, 189(5):779-786.
41. Witherden D.A., Havran W.L. Molecular aspects of epithelial γδT cell regulation. Trends Immunol 2011, 32(6):265-271.
42. Homey B., Alenius H., Müller A., et al. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat Med 2002, 8(2):157-165.
43. Schaerli P., Ebert L., Willimann K., et al. A skin-selective homing mechanism for human immune surveillance T cells. J Exp Med 2004, 199(9):1265-1275.
44. Kunkel E.J., Butcher E.C. Chemokines and the tissue-specific migration of lymphocytes. Immunity 2002, 16(1):1-4.
45. Longley J., Duffy T.P., Kohn S. The mast cell and mast cell disease. J Am Acad Dermatol 1995, 32(4):545-561. quiz 562-564.
46. Wang B., Rieger A., Kilgus O., et al. Epidermal Langerhans cells from normal human skin bind monomeric IgE via Fc epsilon RI. J Exp Med 1992, 175(5):1353-1365.
47. Minegishi Y., Saito M., Nagasawa M., et al. Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome. J Exp Med 2009, 206(6):1291-1301.
48. Kripke M.L. Antigenicity of murine skin tumors induced by ultraviolet light. J Natl Cancer Inst 1974, 53(5):1333-1336.
49. Boyle J., Mackie R.M., Briggs J.D., et al. Cancer, warts, and sunshine in renal transplant patients. A case-control study. Lancet 1984, 1(8379):702-705.
50. Toews G.B., Bergstresser P.R., Streilein J.W. Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB. J Immunol 1980, 124(1):445-453.