Uptake of apolipoprotein e fragment coupled liposomes by cultured brain microvessel endothelial cells and intact brain capillaries

Journal of Drug Targeting

Volumn 17, Issue 8, 2009, Pages 610-618

  Hülsermann, Uta ^a   Hoffmann, Michael M ^b   Massing, Ulrich ^c   Fricker, Gert ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c TUMOR BIOLOGY CENTER   (Germany)

Author keywords

apolipoprotein E; blood brain barrier; brain capillary endothelial cells; Liposomes

Indexed keywords

AMINO ACID; APOLIPOPROTEIN E; APOLIPOPROTEIN E4; CHOLESTEROL; DIPALMITOYLPHOSPHATIDYLETHANOLAMINE; LIPOSOME; LOW DENSITY LIPOPROTEIN RECEPTOR; MACROGOL 2000; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; RHODAMINE; DRUG CARRIER; MACROGOL DERIVATIVE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY; CELL CULTURE; CONFOCAL LASER MICROSCOPY; DRUG COATING; DRUG TARGETING; DRUG UPTAKE; ENDOTHELIUM CELL; FLUORESCENCE MICROSCOPY; HUMAN; LIPID BILAYER; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; ANIMAL; BRAIN; CAPILLARY; CELL LINE; CHEMISTRY; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; DRUG DELIVERY SYSTEM; ENDOCYTOSIS; METABOLISM; MICROVASCULATURE; RAT; SWINE; VASCULAR ENDOTHELIUM;

ANIMALS; APOLIPOPROTEINS E; BLOOD-BRAIN BARRIER; BRAIN; CAPILLARIES; CELL LINE; CELLS, CULTURED; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; LIPOSOMES; MICROSCOPY, CONFOCAL; MICROVESSELS; POLYETHYLENE GLYCOLS; RATS; SWINE;

EID: 70350468673     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.1080/10611860903105986     Document Type: Article

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