Blocking signaling at the level of GLI regulates downstream gene expression and inhibits proliferation of canine osteosarcoma cells

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Shahi, Mehdi Hayat ^a   Holt, Roseline ^a   Rebhun, Robert B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GANT 61; MESSENGER RNA; PROTEIN INHIBITOR; PROTEIN PATCHED 1; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; TRANSCRIPTION FACTOR PAX6; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; INHIBITION KINETICS; NONHUMAN; OSTEOSARCOMA CELL LINE; PAX6 GENE; PROTEIN EXPRESSION; PTCH1 GENE; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ANIMAL; DOG; DRUG EFFECTS; METABOLISM; OSTEOSARCOMA; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DOGS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; OSTEOSARCOMA; PYRIDINES; PYRIMIDINES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84901503380     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0096593     Document Type: Article

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