-
1
-
-
77958508124
-
A mechanism for vertebrate hedgehog signaling: Recruitment to cilia and dissociation of SuFu-Gli protein complexes
-
Tukachinsky H, Lopez LV and Salic A: A mechanism for vertebrate hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes. Jour Cell Bio 191: 415-428, 2010.
-
(2010)
Jour Cell Bio
, vol.191
, pp. 415-428
-
-
Tukachinsky, H.1
Lopez, L.V.2
Salic, A.3
-
3
-
-
51349167818
-
Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling
-
Breunig JJ, Sarkisian MR, Arellano JI, Morozov YM, Ayoub AE, Sojitra S, Wang B, Flavell RA, Rakic P and Town T: Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling. Proc Natl Acad Sci USA 105: 13127-13132, 2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13127-13132
-
-
Breunig, J.J.1
Sarkisian, M.R.2
Arellano, J.I.3
Morozov, Y.M.4
Ayoub, A.E.5
Sojitra, S.6
Wang, B.7
Flavell, R.A.8
Rakic, P.9
Town, T.10
-
4
-
-
77953389464
-
Primary cilia regulate Gli/Hedgehog activation in pancreas
-
Cervantes S., Lau J, Cano DA, Borromeo-Austin C and Hebrok M: Primary cilia regulate Gli/Hedgehog activation in pancreas. Proc Natl Acad Sci USA 107: 10109-10114, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 10109-10114
-
-
Cervantes, S.1
Lau, J.2
Cano, D.A.3
Borromeo-Austin, C.4
Hebrok, M.5
-
5
-
-
79952770440
-
Cilia in the CNS: The quiet organelle claims center stage
-
Louvi A and Grove E: Cilia in the CNS: The quiet organelle claims center stage. Neuron 69: 1046-1060, 2011
-
(2011)
Neuron
, vol.69
, pp. 1046-1060
-
-
Louvi, A.1
Grove, E.2
-
6
-
-
84860536549
-
Molecular pathways: The role of primary cilia in cancer progression and therapeutics with a focus on hedgehog signaling
-
Hassounah NB, Bunch TA and McDermott KM: Molecular pathways: The role of primary cilia in cancer progression and therapeutics with a focus on hedgehog signaling. Clin Cancer Res 18: 2429-2435, 2012
-
(2012)
Clin Cancer Res
, vol.18
, pp. 2429-2435
-
-
Hassounah, N.B.1
Bunch, T.A.2
McDermott, K.M.3
-
7
-
-
69949166247
-
Dual and opposing roles of primary cilia in medulloblastoma development
-
Han YG, Kim HJ, Dlugosz AA, Ellison DW, Gilbertson RJ and Alvarez-Buylla A: Dual and opposing roles of primary cilia in medulloblastoma development. Nat Med 15: 1062-1065, 2009.
-
(2009)
Nat Med
, vol.15
, pp. 1062-1065
-
-
Han, Y.G.1
Kim, H.J.2
Dlugosz, A.A.3
Ellison, D.W.4
Gilbertson, R.J.5
Alvarez-Buylla, A.6
-
8
-
-
84932177885
-
Primary cilia and cancer
-
K.L. Tucker and T. Caspary, eds., Springer-Verlag, New York
-
Hou S and Han Y-G: Primary cilia and cancer. In: K.L. Tucker and T. Caspary, eds., Cilia and Nervous System Development and FunctionSpringer-Verlag, New York pp. 209-228, 2013.
-
(2013)
Cilia and Nervous System Development and Function
, pp. 209-228
-
-
Hou, S.1
Han, Y.-G.2
-
9
-
-
74549177523
-
Primary ciliogenesis defects are associated with human astrocytoma/glioblastoma cells
-
Moser, JJ., Fritzler MJ and Rattner JB: Primary ciliogenesis defects are associated with human astrocytoma/glioblastoma cells. BMC Cancer 9: 448, 2009.
-
(2009)
BMC Cancer
, vol.9
, pp. 448
-
-
Moser, J.J.1
Fritzler, M.J.2
Rattner, J.B.3
-
10
-
-
58149159900
-
Sporadic clear cell renal cell carcinoma but not the papillary type is characterized by severely reduced frequency of primary cilia
-
Schraml P, Frew IJ, Thoma CR, Boysen G, Struckmann K, Krek W and Moch H: Sporadic clear cell renal cell carcinoma but not the papillary type is characterized by severely reduced frequency of primary cilia. Mod Pathol 22: 31-36, 2008.
-
(2008)
Mod Pathol
, vol.22
, pp. 31-36
-
-
Schraml, P.1
Frew, I.J.2
Thoma, C.R.3
Boysen, G.4
Struckmann, K.5
Krek, W.6
Moch, H.7
-
11
-
-
58349099851
-
Pancreatic Cancer and precursor pancreatic intraepithelial neoplasia lesions are devoid of primary cilia
-
Seeley ES, Carrière C, Goetze T, Longnecker DS and Korc M: Pancreatic Cancer and precursor pancreatic intraepithelial neoplasia lesions are devoid of primary cilia. Cancer Res 69: 422-430, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 422-430
-
-
Seeley, E.S.1
Carrière, C.2
Goetze, T.3
Longnecker, D.S.4
Korc, M.5
-
12
-
-
77957325256
-
Primary cilia are decreased in breast cancer: Analysis of a collection of human breast cancer cell lines and tissues
-
Yuan K, Frolova N, Xie Y, Wang D, Cook L, Kwon YJ, Steg AD, Serra R and Frost AR: Primary cilia are decreased in breast cancer: analysis of a collection of human breast cancer cell lines and tissues. Jour Histochem Cytochem 58: 857-870, 2010.
-
(2010)
Jour Histochem Cytochem
, vol.58
, pp. 857-870
-
-
Yuan, K.1
Frolova, N.2
Xie, Y.3
Wang, D.4
Cook, L.5
Kwon, Y.J.6
Steg, A.D.7
Serra, R.8
Frost, A.R.9
-
13
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang da W, Sherman BT and Lempicki RA: Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57, 2009.
-
(2009)
Nat Protoc
, vol.4
, pp. 44-57
-
-
Huang Da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
14
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES and Mesirov JP: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102: 15545-1550, 2005.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15545-21550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
Mesirov, J.P.11
-
16
-
-
33747885673
-
[8] Bioconductor: An Open Source Framework for Bioinformatics and Computational Biology
-
DOI 10.1016/S0076-6879(06)11008-3, PII S0076687906110083, DNA Microarrays, Part B: Databases and Statistics
-
Reimers M and Carey VJ: Bioconductor: an open source framework for bioinformatics and computational biology. Methods Enzymol 411: 119-134, 2006. (Pubitemid 44291424)
-
(2006)
Methods in Enzymology
, vol.411
, pp. 119-134
-
-
Reimers, M.1
Carey, V.J.2
-
17
-
-
0242333835
-
Normalization of cDNA microarray data
-
DOI 10.1016/S1046-2023(03)00155-5
-
Smyth GK and Speed TP: Normalization of cDNA microarray data. Methods 31: 265-273, 2003. (Pubitemid 37338763)
-
(2003)
Methods
, vol.31
, Issue.4
, pp. 265-273
-
-
Smyth, G.K.1
Speed, T.2
-
18
-
-
4544341015
-
Linear models and empirical Bayes methods for assessing differential expression in microarray experiments
-
Smyth GK: Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 3: Article 3, 2004.
-
(2004)
Stat Appl Genet Mol Biol
, vol.3
, pp. 3
-
-
Smyth, G.K.1
-
19
-
-
0001138328
-
A K-means clustering algorithm
-
Hartigan JA and Wong MA: A K-means clustering algorithm. Appl Stat 28: 100-108, 1979.
-
(1979)
Appl Stat
, vol.28
, pp. 100-108
-
-
Hartigan, J.A.1
Wong, M.A.2
-
20
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
DOI 10.1038/ng1847, PII NG1847
-
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA and Reich D: Principal components analysis corrects forstratification in genome-wide association studies. Nat Genet 38: 904-909, 2006. (Pubitemid 44141658)
-
(2006)
Nature Genetics
, vol.38
, Issue.8
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
21
-
-
22044433869
-
Gene expression signatures for colorectal cancer microsatellite status and HNPCC
-
Kruhøffer M, Jensen JL, Laiho P, Dyrskjøt L, Salovaara R, Arango D, Birkenkamp-Demtroder K, Sørensen FB, Christensen LL, Buhl L, Mecklin JP, Järvinen H, Thykjaer T, Wikman FP, Bech-Knudsen F, Juhola M, Nupponen NN, Laurberg S, Andersen CL, Aaltonen LA and Ørntoft TF: Gene expression signatures for colorectal cancer microsatellite status and HNPCC. Brit Jour Cancer 92: 2240-2248, 2005.
-
(2005)
Brit Jour Cancer
, vol.92
, pp. 2240-2248
-
-
Kruhøffer, M.1
Jensen, J.L.2
Laiho, P.3
Dyrskjøt, L.4
Salovaara, R.5
Arango, D.6
Birkenkamp-Demtroder, K.7
Sørensen, F.B.8
Christensen, L.L.9
Buhl, L.10
Mecklin, J.P.11
Järvinen, H.12
Thykjaer, T.13
Wikman, F.P.14
Bech-Knudsen, F.15
Juhola, M.16
Nupponen, N.N.17
Laurberg, S.18
Andersen, C.L.19
Aaltonen, L.A.20
Ørntoft, T.F.21
more..
-
22
-
-
44449178672
-
Unregulated smooth-muscle myosin in human intestinal neoplasia
-
DOI 10.1073/pnas.0801213105
-
Alhopuro P, Phichith D, Tuupanen S, Sammalkorpi H, Nybondas M, Saharinen J, Robinson JP, Yang Z, Chen LQ, Orntoft T, Mecklin JP, Järvinen H, Eng C, Moeslein G, Shibata D, Houlston RS, Lucassen A, Tomlinson IP, Launonen V, Ristimäki A, Arango D, Karhu A, Sweeney HL and Aaltonen LA: Unregulated smooth-muscle myosin in human intestinal neoplasia. Proc Natl Acad Sci USA 105: 5513-5518, 2008. (Pubitemid 351753894)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.14
, pp. 5513-5518
-
-
Alhopuro, P.1
Phichith, D.2
Tuupanen, S.3
Sammalkorpi, H.4
Nybondas, M.5
Saharinen, J.6
Robinson, J.P.7
Yang, Z.8
Chen, L.-Q.9
Orntoft, T.10
Mecklin, J.-P.11
Jarvinen, H.12
Eng, C.13
Moeslein, G.14
Shibata, D.15
Houlston, R.S.16
Lucassen, A.17
Tomlinson, I.P.M.18
Launonen, V.19
Ristimaki, A.20
Arango, D.21
Karhu, A.22
Sweeney, H.L.23
Aaltonen, L.A.24
more..
-
23
-
-
77950441069
-
Seromic profiling of ovarian and pancreatic cancer
-
Gnjatic S, Ritter E, Büchler MW, Giese NA, Brors B, Frei C, Murray A, Halama N, Zörnig I, Chen YT, Andrews C, Ritter G, Old LJ, Odunsi K and Jäger D: Seromic profiling of ovarian and pancreatic cancer. Proc Natl Acad Sci USA 107: 5088-5093, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5088-5093
-
-
Gnjatic, S.1
Ritter, E.2
Büchler, M.W.3
Giese, N.A.4
Brors, B.5
Frei, C.6
Murray, A.7
Halama, N.8
Zörnig, I.9
Chen, Y.T.10
Andrews, C.11
Ritter, G.12
Old, L.J.13
Odunsi, K.14
Jäger, D.15
-
24
-
-
84876864559
-
Identification and Functional Characterization of FMN2, a Regulator of the Cyclin-Dependent Kinase Inhibitor p21
-
Yamada K, Ono M, Perkins ND, Rocha S and Lamond AI: Identification and Functional Characterization of FMN2, a Regulator of the Cyclin-Dependent Kinase Inhibitor p21.Molec Cell 7: 922-933, 2013.
-
(2013)
Molec Cell
, vol.7
, pp. 922-933
-
-
Yamada, K.1
Ono, M.2
Perkins, N.D.3
Rocha, S.4
Lamond, A.I.5
-
25
-
-
26844498200
-
A DNA microarray survey of gene expression in normal human tissues
-
Shyamsundar R, Kim YH, Higgins JP, Montgomery K, Jorden M, Sethuraman A, van de Rijn M, Botstein D, Brown PO and Pollack JR: A DNA microarray survey of gene expression in normal human tissues. Genome Bio 6: R22.
-
Genome Bio
, vol.6
-
-
Shyamsundar, R.1
Kim, Y.H.2
Higgins, J.P.3
Montgomery, K.4
Jorden, M.5
Sethuraman, A.6
Van De Rijn, M.7
Botstein, D.8
Brown, P.O.9
Pollack, J.R.10
-
26
-
-
33646422506
-
Rab23: What exactly does it traffic?
-
DOI 10.1002/jbm.a.30764
-
Wang Y, Ng EL and Tang BL: Rab23: what exactly does it traffic? Traffic 7: 746-750, 2006. (Pubitemid 43676981)
-
(2006)
Traffic
, vol.7
, Issue.6
, pp. 746-750
-
-
Wang, Y.1
Ng, E.L.2
Tang, B.L.3
-
27
-
-
2542555722
-
FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues
-
DOI 10.1242/dev.01122
-
Bulgakov OV, Eggenschwiler JT, Hong DH, Anderson KV and Li T: FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissue. Development 131: 2149-2159, 2004. (Pubitemid 38702046)
-
(2004)
Development
, vol.131
, Issue.9
, pp. 2149-2159
-
-
Bulgakov, O.V.1
Eggenschwiler, J.T.2
Hong, D.-H.3
Anderson, K.V.4
Li, T.5
-
28
-
-
49649127726
-
Integrative genomics identifies RAB23 as an invasive mediator gene in diffuse-type gastric cancer
-
Hou Q, Wu YH, Grabsch H, Zhu Y, Leong SH, Ganesan K, Cross D, Tan LK, Tao J, Gopalakrishnan V, Tang BL, Kon OL and Tan P: Integrative genomics identifies RAB23 as an invasive mediator gene in diffuse-type gastric cancer. Cancer Res 68: 4624-4630, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 4624-4630
-
-
Hou, Q.1
Wu, Y.H.2
Grabsch, H.3
Zhu, Y.4
Leong, S.H.5
Ganesan, K.6
Cross, D.7
Tan, L.K.8
Tao, J.9
Gopalakrishnan, V.10
Tang, B.L.11
Kon, O.L.12
Tan, P.13
-
29
-
-
85041330265
-
Transcriptome analysis of human gastric cancer. Mamm Genome 16: 942-954, 2006. 30 di Magliano MP: Hedgehog signalling in cancer formation and maintenance
-
Oh JH, Yang JO, Hahn Y, Kim MR, Byun SS, Jeon YJ, Kim JM, Song KS, Noh SM, Kim S, Yoo HS, Kim YS and Kim NS: Transcriptome analysis of human gastric cancer. Mamm Genome 16: 942-954, 2006. 30 di Magliano MP: Hedgehog signalling in cancer formation and maintenance. Nat Rev Cancer 3: 903-911, 2013.
-
(2013)
Nat Rev Cancer
, vol.3
, pp. 903-911
-
-
Oh, J.H.1
Yang, J.O.2
Hahn, Y.3
Kim, M.R.4
Byun, S.S.5
Jeon, Y.J.6
Kim, J.M.7
Song, K.S.8
Noh, S.M.9
Kim, S.10
Yoo, H.S.11
Kim, Y.S.12
Kim, N.S.13
|