Enhanced antitumor efficacy of folate modified amphiphilic nanoparticles through co-delivery of chemotherapeutic drugs and genes

Biomaterials

Volumn 35, Issue 24, 2014, Pages 6369-6378

  Yu, Bojie ^a   Tang, Cui ^a   Yin, Chunhua ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Amphiphilic nanoparticles; Antitumor efficacy; Co delivery; FA modification; Hydrophilic modification; Hydrophobic modification

Indexed keywords

GENES; HYDROPHILICITY; HYDROPHOBICITY; LINOLEIC ACID; NANOPARTICLES;

AMPHIPHILICS; ANTI-TUMOR EFFICACY; CO DELIVERIES; FA MODIFICATION; HYDROPHILIC MODIFICATION; HYDROPHOBIC MODIFICATION;

GRAFTING (CHEMICAL);

ANTINEOPLASTIC AGENT; BIRC5 PROTEIN, MOUSE; BOVINE SERUM ALBUMIN; CHITOSAN; DEOXYRIBONUCLEASE I; FOLIC ACID; INHIBITOR OF APOPTOSIS PROTEIN; LINOLEIC ACID; MALIC ACID DERIVATIVE; MESSENGER RNA; NANOPARTICLE; PACLITAXEL; POLY(MALIC ACID); POLYMER; REPRESSOR PROTEIN; SURFACTANT;

ADSORPTION; ANIMAL; APOPTOSIS; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG EFFECTS; ENDOCYTOSIS; FEMALE; GENE TRANSFER; GENETICS; HUMAN; METABOLISM; MOUSE; PARTICLE SIZE; STATIC ELECTRICITY; TUMOR CELL LINE;

ADSORPTION; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHITOSAN; DEOXYRIBONUCLEASE I; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; FEMALE; FOLIC ACID; GENE TRANSFER TECHNIQUES; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; LINOLEIC ACID; MALATES; MICE; NANOPARTICLES; PACLITAXEL; PARTICLE SIZE; POLYMERS; REPRESSOR PROTEINS; RNA, MESSENGER; SERUM ALBUMIN, BOVINE; STATIC ELECTRICITY; SURFACE-ACTIVE AGENTS;

EID: 84901457230     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.04.095     Document Type: Article

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