An adaptable pentaloop defines a robust neomycin-B RNA aptamer with conditional ligand-bound structures

RNA

Volumn 20, Issue 6, 2014, Pages 815-824

  Ilgu, Muslum ^a,b   Fulton, D Bruce ^b   Yennamalli, Ragothaman M ^b,d   Lamm, Monica H ^c   Sen, Taner Z ^b   Nilsen Hamilton, Marit ^a,b  

^a IOWA STATE UNIVERSITY   (United States)

^b IOWA STATE UNIVERSITY   (United States)

^c Iowa State University   (United States)

^d RICE UNIVERSITY   (United States)

Author keywords

Aminoglycoside; Aptamer; Structure

Indexed keywords

2 AMINOPURINE; APTAMER; FRAMYCETIN; LIGAND; PAROMOMYCIN; RIBOSTAMYCIN; RNA;

ARTICLE; BINDING AFFINITY; FLUORESCENCE; HYDROGEN BOND; HYDROPHOBICITY; IONIC STRENGTH; LIGAND BINDING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RNA STRUCTURE; STEADY STATE;

AMINOGLYCOSIDE; APTAMER; STRUCTURE;

2-AMINOPURINE; AMINOGLYCOSIDES; APTAMERS, NUCLEOTIDE; BINDING SITES; FRAMYCETIN; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIGANDS; NUCLEIC ACID CONFORMATION; OSMOLAR CONCENTRATION; RNA; SUBSTRATE SPECIFICITY;

EID: 84901452318     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.041145.113     Document Type: Article

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