Survey of cervical spine research society members on the use of high-dose steroids for acute spinal cord injuries

Spine

Volumn 39, Issue 12, 2014, Pages 971-977

  Schroeder, Gregory D ^a   Kwon, Brian K ^b   Eck, Jason C ^c   Savage, Jason W ^a   Hsu, Wellington K ^a   Patel, Alpesh A ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c Center for Sports Medicine and Orthopaedics Chattanooga   (United States)

Author keywords

acute spinal cord injury; Cervical Spine Research Society; CSRS; high dose steroid; methylprednisolone; survey

Indexed keywords

METHYLPREDNISOLONE; STEROID; CORTICOSTEROID;

ACUTE DISEASE; ARTICLE; CERVICAL SPINE; DISEASE SEVERITY; DRUG CONTRAINDICATION; DRUG MEGADOSE; DRUG USE; EMERGENCY HEALTH SERVICE; GASTROINTESTINAL HEMORRHAGE; HUMAN; MEDICAL SOCIETY; MEDICOLEGAL ASPECT; PRIORITY JOURNAL; QUESTIONNAIRE; SEPSIS; SPINAL CORD INJURY; SURGEON; THORACOLUMBAR SPINE; CLINICAL PRACTICE; COMPLICATION; CONTRAINDICATIONS; CONVALESCENCE; FEAR; HEALTH CARE ORGANIZATION; HEALTH CARE SURVEY; HEALTH PERSONNEL ATTITUDE; MALPRACTICE; NEUROSURGERY; ORTHOPEDICS; SPINAL CORD INJURIES; STATISTICS AND NUMERICAL DATA; TIME; TREATMENT OUTCOME; UNITED STATES;

ACUTE DISEASE; ADRENAL CORTEX HORMONES; ATTITUDE OF HEALTH PERSONNEL; FEAR; GASTROINTESTINAL HEMORRHAGE; HEALTH CARE SURVEYS; HUMANS; MALPRACTICE; METHYLPREDNISOLONE; NEUROSURGERY; ORTHOPEDICS; PHYSICIAN'S PRACTICE PATTERNS; RECOVERY OF FUNCTION; SEPSIS; SOCIETIES, SCIENTIFIC; SPINAL CORD INJURIES; TIME FACTORS; TRAUMA CENTERS; TREATMENT OUTCOME; UNITED STATES;

EID: 84901444769     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0000000000000297     Document Type: Article

References (21)

1. Chiles BW III, Cooper PR. Acute spinal injury. N Engl J Med 1996; 334: 514-20.
2. Nobunaga AI, Go BK, Karunas RB. Recent demographic and injury trends in people served by the Model Spinal Cord Injury Care Systems. Arch Phys Med Rehabil 1999; 80: 1372-82.
3. Wyndaele M, Wyndaele JJ. Incidence, prevalence and epidemiology of spinal cord injury: what learns a worldwide literature survey? Spinal Cord 2006; 44: 523-9.
4. Tator CH, Fehlings MG. Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms. J Neurosurg 1991; 75: 15-26.
5. Amar AP, Levy ML. Pathogenesis and pharmacological strategies for mitigating secondary damage in acute spinal cord injury. Neu-rosurgery 1999; 44: 1027-39; discussion 1039-40.
6. Profyris C, Cheema SS, Zang D, et al. Degenerative and regenerative mechanisms governing spinal cord injury. Neurobiol Dis 2004; 15: 415-36.
7. Sekhon LH, Fehlings MG. Epidemiology, demographics, and pathophysiology of acute spinal cord injury. Spine (Phila Pa 1976) 2001; 26 (suppl 24): S2-12.
8. Fehlings MG, Vaccaro A, Wilson JR, et al. Early versus delayed decompression for traumatic cervical spinal cord injury: Results of the Surgical Timing in Acute Spinal Cord Injury Study (STASCIS). PLoS One 2012; 7: e32037.
9. Bracken MB, Shepard MJ, Collins WF, et al. A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study. N Engl J Med 1990; 322: 1405-11.
10. Bracken MB, Shepard MJ, Holford TR, et al. Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord Injury Study. JAMA 1997; 277: 1597-604.
11. Hurlbert RJ. Methylprednisolone for acute spinal cord injury: an inappropriate standard of care. J Neurosurg 2000; 93 (suppl 1): 1-7.
12. Hurlbert RJ. The role of steroids in acute spinal cord injury: an evidence-based analysis. Spine (Phila Pa 1976) 2001; 26 (suppl 24): S39-46.
13. Matsumoto T, Tamaki T, Kawakami M, et al. Early complications of high-dose methylprednisolone sodium succinate treatment in the follow-up of acute cervical spinal cord injury. Spine (Phila Pa 1976) 2001; 26: 426-30.
14. Molano Mdel R, Broton JG, Bean JA, et al. Complications associated with the prophylactic use of methylprednisolone during surgical stabilization after spinal cord injury. J Neurosurg 2002; 96 (suppl 3): 267-72.
15. Hurlbert RJ, Hadley MN, Walters BC, et al. Pharmacological therapy for acute spinal cord injury. Neurosurgery 2013; 72 (suppl 2): 93-105.
16. Leypold BG, Flanders AE, Schwartz ED, et al. The impact of meth-ylprednisolone on lesion severity following spinal cord injury. Spine (Phila Pa 1976) 2007; 32: 373-8; discussion 379-81.
17. Ito Y, Sugimoto Y, Tomioka M, et al. Does high-dose methylpred-nisolone sodium succinate really improve neurological status in patient with acute cervical cord injury?: a prospective study about neurological recovery and early complications. Spine (Phila Pa 1976) 2009; 34: 2121-4.
18. Pollard ME, Apple DF. Factors associated with improved neurologic outcomes in patients with incomplete tetraplegia. Spine (Phila Pa 1976) 2003; 28: 33-9.
19. Eck JC, Nachtigall D, Humphreys SC, et al. Questionnaire survey of spine surgeons on the use of methylprednisolone for acute spinal cord injury. Spine (Phila Pa 1976) 2006; 31: E250-3.
20. Druschel C, Schaser KD, Schwab JM. Current practice of meth-ylprednisolone administration for acute spinal cord injury in Germany: a national survey. Spine (Phila Pa 1976) 2013; 38: E669-77.
21. Hurlbert RJ, Hamilton MG. Methylprednisolone for acute spinal cord injury: 5-year practice reversal. Can J Neurol Sci 2008; 35: 41-5.