Current practice of methylprednisolone administration for acute spinal cord injury in Germany: A national survey

Spine

Volumn 38, Issue 11, 2013, Pages

  Druschel, Claudia ^a   Schaser, Klaus Dieter ^a   Schwab, Jan M ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Methylprednisolone; NASCIS; Spinal cord injury; Standard of care

Indexed keywords

METHYLPREDNISOLONE SODIUM SUCCINATE;

ARTICLE; CORTICOSTEROID THERAPY; DRUG EFFICACY; DRUG MEGADOSE; GERMANY; HOSPITAL DEPARTMENT; HUMAN; MAJOR CLINICAL STUDY; MEDICOLEGAL ASPECT; PRACTICE GUIDELINE; PRIORITY JOURNAL; QUESTIONNAIRE; SPECIALIZATION; SPINAL CORD INJURY; TEACHING HOSPITAL; TREATMENT OUTCOME;

ACUTE DISEASE; GERMANY; HEALTH CARE SURVEYS; HUMANS; METHYLPREDNISOLONE HEMISUCCINATE; NEUROPROTECTIVE AGENTS; NORTH AMERICA; QUESTIONNAIRES; SPINAL CORD INJURIES;

EID: 84879074816     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e31828e4dce     Document Type: Article

References (34)

1. Thietje R, Kowald B, Hirschfeld S. What are the causes of death in patients with spinal cord injury today?-a descriptive analysis of 102 cases. Rehabilitation (Stuttg) 2011; 50: 251-4.
2. Schwab JM, Brechtel K, Mueller CA, et al. Experimentelle Therapiestrategien akuter Rückenmarkverletzung - eine integrative Perspektive. Deutsches Aerzteblatt, 2004; 101: A1422-34.
3. Ducker TB. Treatment of spinal-cord injury. N Engl J Med 1990; 322: 1459-61.
4. Rossignol S, Schwab M, Schwartz M, et al. Spinal cord injury: time to move? J Neurosci 2007; 27: 11782-92.
5. Pandya KA, Weant KA, Cook AM. High-dose methylprednisolone in acute spinal cord injuries: proceed with caution. Orthopedics 2010; 33: 327-31.
6. Anderson DK, Hall ED. Pathophysiology of spinal cord trauma. Ann Emerg Med 1993; 22: 987-92.
7. Bracken MB, Holford TR. Effects of timing of methylprednisolone or naloxone administration on recovery of segmental and long-tract neurological function in NASCIS 2. J Neurosurg 1993; 79: 500-7.
8. Felleiter P, Müller N, Schumann F, et al. Changes in the use of the methylprednisolone protocol for traumatic spinal cord injury in Switzerland. Spine (Phila Pa 1976) 2012; 37: 953-6.
9. Roberts I, Yates D, Sandercock P, et al. Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebocontrolled trial. Lancet 2004; 364: 1321-8.
10. Short D. Is the role of steroids in acute spinal cord injury now resolved? Curr Opin Neurol 2001; 14: 759-63.
11. Riegger T, Conrad S, Schluesener HJ, et al. Immune depression syndrome following human spinal cord injury (SCI): a pilot study. Neuroscience 2009; 158: 1194-9.
12. Furlan JC, Krassioukov AV, Fehlings MG. Hematologic abnormalities within the first week after acute isolated traumatic cervical spinal cord injury: a case-control cohort study. Spine (Phila Pa 1976) 2006; 31: 2674-83.
13. Failli V, Kopp MA, Gericke C, et al. Functional neurological recovery after spinal cord injury is impaired in patients with infections. Brain 2012; 135: 3238-50.
14. Hurlbert RJ. The role of steroids in acute spinal cord injury: an evidence-based analysis. Spine (Phila Pa 1976) 2001; 26 (suppl 24) : S39-46.
15. Hurlbert RJ. Methylprednisolone for acute spinal cord injury: an inappropriate standard of care. J Neurosurg 2000; 93 (suppl 1) : 1-7.
16. Hadley MN, Walters BC, Grabb PA, et al. Pharmacological therapy after acute spinal cord injury. Neurosurgery 2002; 50 (suppl) : 63-72.
17. Deutsche Gesellschaft für Unfallchirurgie. S3-Leitlinie Polytrauma/Schwerverletzten-Behandlung. July 2011. Available at: http://www. awmf.org. Accessed August 6, 2012.
18. Dietz V. Querschnittlähmung, Leitlinien für Diagnostik und Therapie in der Neurologie der Deutschen Gesellschaft für Neurologie. Diener, Putzki, Berlit eds. Stuttgart: Thieme Verlag; 2008.
19. Curt A, Abel R, Bruner H, et al. Querschnittlähmung, Leitlinien für Diagnostik und Therapie in der Neurologie der Deutschen Gesellschaft für Neurologie. Diener, Putzki, Berlit eds. Stuttgart: Thieme Verlag; 2012.
20. Hurlbert RJ, Hamilton MG. Methylprednisolone for acute spinal cord injury: 5-year practice reversal. Can J Neurol Sci 2008; 35: 41-5.
21. Hurlbert RJ, Moulton R. Why do you prescribe methylprednisolone for acute spinal cord injury? A Canadian perspective and a position statement. Can J Neurol Sci 2002; 29: 236-9.
22. Fillion Fl. Estimating bias due to nonresponse in mail surveys. Public Opinion Q 1976; 39: 482-92.
23. Molloy S, Price M, Casey AT. Questionnaire survey of the views of the delegates at the European Cervical Spine Research Society meeting on the administration of methylprednisolone for acute traumatic spinal cord injury. Spine (Phila Pa 1976) 2001; 26: E562-4.
24. Frampton AE, Eynon CA. High dose methylprednisolone in the immediate management of acute, blunt spinal cord injury: what is the current practice in emergency departments, spinal units, and neurosurgical units in the UK? Emerg Med J 2006; 23: 550-3.
25. Federal Chamber of Physicians. Medical Statistics 2010. Available at: http://www.bundesaerztekammer.de. Accessed May 5, 2012.
26. Parent S, Barchi S, LeBreton M, et al. The impact of specialized centers of care for spinal cord injury on length of stay, complications, and mortality: a systematic review of the literature. J Neurotrauma 2011; 28: 1363-70.
27. Vellman PW, Hawkes AP, Lammertse DP. Administration of corticosteroids for acute spinal cord injury: the current practice of trauma medical directors and emergency medical system physician advisors. Spine (Phila Pa 1976) 2003; 28: 941-7.
28. Nicholas JS, Selassie AW, Lineberry LA, et al. Use and determinants of the methylprednisolone protocol for traumatic spinal cord injury in South Carolina acute care hospitals. J Trauma 2009; 66: 1446-50; discussion 1450.
29. Bledsoe BE, Wesley AK, Salomone JP; National Association of EMS Physicians Standards and Clinical Practice Committee. High-dose steroids for acute spinal cord injury in emergency medical services. Prehosp Emerg Care 2004; 8: 313-6.
30. Edwards P, Arango M, Balica L, et al. CRASH trial collaborators. Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injuryoutcomes at 6 months. Lancet 2005; 365: 1957-9.
31. Hugenholtz H, Cass DE, Dvorak MF, et al. High-dose methylprednisolone for acute closed spinal cord injury - only a treatment option. Can J Neurol Sci 2002; 29: 227-35.
32. Cabana MD, Rand CS, Powe NR, et al. Why don't physicians follow clinical practice guidelines? A framework for improvement. JAMA 1999; 282: 1458-65.
33. Sinuff T, Cook D, Giacomini M, et al. Facilitating clinician adherence to guidelines in the intensive care unit: A multicenter, qualitative study. Crit Care Med 2007; 35: 2083-9.
34. Paiva EF, Rocha AT. How to implement a guideline from theory to practice: the example of the venous thromboembolism prophylaxis. Acta Med Port 2009; 22: 21-32. Spinal Cord Research Foundation