Detection of follicular transport of lidocaine and metabolism in adipose tissue in pig ear skin by DESI mass spectrometry imaging

Analytical and Bioanalytical Chemistry

Volumn 406, Issue 15, 2014, Pages 3735-3742

  D'Alvise, Janina ^a   Mortensen, Rasmus ^b   Hansen, Steen H ^a   Janfelt, Christian ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b LEO PHARMA A S   (Denmark)

Author keywords

DESI; Drugs; Lidocaine; Mass spectrometry imaging; Pig ear skin; Topical

Indexed keywords

ELECTROSPRAY IONIZATION; EXPERIMENTS; MAMMALS; MASS SPECTROMETRY; METABOLISM; PHYSIOLOGY;

DESI; DRUGS; LIDOCAINE; MASS-SPECTROMETRY IMAGING; TOPICAL;

TISSUE;

LIDOCAINE; SOLVENT;

ADIPOSE TISSUE; ANIMAL; CHEMISTRY; DRUG EFFECTS; EAR; ELECTROSPRAY MASS SPECTROMETRY; EPIDERMIS; METABOLISM; PIG; SKIN; TOPICAL DRUG ADMINISTRATION; TRANSPORT AT THE CELLULAR LEVEL;

ADIPOSE TISSUE; ADMINISTRATION, TOPICAL; ANIMALS; BIOLOGICAL TRANSPORT; EAR; EPIDERMIS; LIDOCAINE; SKIN; SOLVENTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SWINE;

EID: 84901438048     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-014-7802-z     Document Type: Article

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