Skin research and drug localization with receptor microscopic autoradiography

Experimental Dermatology

Volumn 17, Issue 2, 2008, Pages 133-138

  Stumpf, Walter E ^a,b,e   Hayakawa, Naohiko ^c   Bidmon, Hans Juergen ^d  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b Intl Institute of Drug Distribution Cytopharmacology and Cytotoxicology   (United States)

^c CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^d C and O Vogt Institute of Brain Research   (Germany)

^e NONE   (United States)

Author keywords

Autoradiography; Drug localization; Hair; Imaging; Keratinocytes; Skin penetration; Target cells; Topical application

Indexed keywords

CALCITRIOL; ESTRADIOL; RETINOIC ACID; TRITIUM; VITAMIN D; VITAMIN D RECEPTOR;

ARTIFACT REDUCTION; AUTORADIOGRAPHY; DOSE RESPONSE; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG EXCRETION; DRUG MECHANISM; DRUG MEGADOSE; DRUG METABOLISM; DRUG PENETRATION; DRUG RECEPTOR BINDING; DRUG RESEARCH; DRUG RETENTION; DRUG TISSUE LEVEL; FREEZING; FROZEN SECTION; HUMAN; IMMUNOCYTOCHEMISTRY; IN VIVO STUDY; ISOTOPE LABELING; LOW DRUG DOSE; MOLECULAR IMAGING; NONHUMAN; PSORIASIS; REVIEW; SKIN; THAWING; WOUND HEALING;

ADMINISTRATION, TOPICAL; ANIMALS; AUTORADIOGRAPHY; DRUG DELIVERY SYSTEMS; HUMANS; KERATINOCYTES; MICROSCOPY; PHARMACEUTICAL PREPARATIONS; RECEPTORS, CELL SURFACE; SKIN; TISSUE DISTRIBUTION;

EID: 38349077455     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2007.00636.x     Document Type: Review

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