A nanocarrier system for the delivery of nucleic acids targeted to a pancreatic beta cell line

Biomaterials

Volumn 35, Issue 24, 2014, Pages 6430-6438

  Yamada, Yuma ^a   Tabata, Mai ^a   Yasuzaki, Yukari ^a   Nomura, Masatoshi ^b   Shibata, Atsushi ^c   Ibayashi, Yuta ^b   Taniguchi, Yosuke ^c   Sasaki, Shigeki ^c   Harashima, Hideyoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY HOSPITAL   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

Diabetes; MicroRNA; MIN6 cell; Multifunctional envelope type nano device (MEND); Nucleic acids delivery; Pancreatic cells

Indexed keywords

BIOMOLECULES; CELL CULTURE; GENE EXPRESSION; GLUCOSE; INSULIN; MEDICAL PROBLEMS; PHYSIOLOGY; RNA;

BLOOD GLUCOSE LEVEL; CONFOCAL LASER SCANNING MICROSCOPY; FLOW CYTOMETRY ANALYSIS; MICRORNAS; MIN6 CELLS; MULTIFUNCTIONAL ENVELOPE-TYPE NANO DEVICES; NUCLEIC ACIDS DELIVERIES; PANCREATIC BETA CELLS;

CELLS;

ANTISENSE OLIGONUCLEOTIDE; GLUCOSE; INSULIN; LIPID; MICRORNA; MIRN375 MICRORNA, MOUSE; NANOPARTICLE; NUCLEIC ACID;

ANIMAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; ENDOCYTOSIS; GENE SILENCING; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; INTRACELLULAR SPACE; METABOLISM; MOUSE; PANCREAS ISLET BETA CELL; SECRETION (PROCESS);

ANIMALS; CELL LINE; CELL SURVIVAL; ENDOCYTOSIS; GENE KNOCKDOWN TECHNIQUES; GENE TRANSFER TECHNIQUES; GLUCOSE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; INTRACELLULAR SPACE; LIPIDS; MICE; MICRORNAS; NANOPARTICLES; NUCLEIC ACIDS; OLIGONUCLEOTIDES, ANTISENSE; TRANSFECTION;

EID: 84901428283     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.04.017     Document Type: Article

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