Network Analyses Reveal Pervasive Functional Regulation Between Proteases in the Human Protease Web

PLoS Biology

Volumn 12, Issue 5, 2014, Pages

  Fortelny, Nikolaus ^a   Cox, Jennifer H ^a,b   Kappelhoff, Reinhild ^a   Starr, Amanda E ^a,c   Lange, Philipp F ^a   Pavlidis, Paul ^a   Overall, Christopher M ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b Centre for Blood Research University of British Columbia ^*  (Canada)

^c UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; LEUKOCYTE ELASTASE; NEUTROPHIL COLLAGENASE; PROTEINASE; PROTEINASE INHIBITOR; PROTEOME; SERINE PROTEINASE INHIBITOR; SERPINA1; UNCLASSIFIED DRUG; ALPHA 1 ANTITRYPSIN; MMP8 PROTEIN, HUMAN; SERPINA1 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME ISOLATION; ENZYME REGULATION; HUMAN; HUMAN TISSUE; IN VIVO STUDY; MATHEMATICAL COMPUTING; MOUSE; NEUTROPHIL; NONHUMAN; PHENOTYPE; PREDICTION; PROTEIN CLEAVAGE; PROTEIN INTERACTION; ANIMAL; CYTOLOGY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; METABOLISM; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEOMICS;

ALPHA 1-ANTITRYPSIN; ANIMALS; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; HUMANS; LEUKOCYTE ELASTASE; MATRIX METALLOPROTEINASE 8; MICE; NEUTROPHILS; PROTEIN INTERACTION MAPPING; PROTEOLYSIS; PROTEOME; PROTEOMICS;

EID: 84901418451     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001869     Document Type: Article

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