Epidermal growth factor receptor inhibition slows progression of diabetic nephropathy in association with a decrease in endoplasmic reticulum stress and an increase in autophagy

Diabetes

Volumn 63, Issue 6, 2014, Pages 2063-2072

  Zhang, Ming Zhi ^a   Wang, Yinqui ^a   Paueksakon, Paisit ^a   Harris, Raymond C ^a,b  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ATG 12 PROTEIN; BECLIN; COLLAGEN TYPE 1; COLLAGEN TYPE 4; CONNECTIVE TISSUE GROWTH FACTOR; CREATININE; ERLOTINIB; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IMMUNOGLOBULIN; INITIATION FACTOR 4B; LC3A II PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN; PROTEIN KINASE; PROTEIN KINASE RNA LIKE ER KINASE; PROTEIN P62; S6 KINASE; ULK1 PROTEIN; UNCLASSIFIED DRUG;

ALBUMINURIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; CELL DEATH; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE COURSE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; EPITHELIUM CELL; GLOMERULAR DYSFUNCTION; GLOMERULAR INJURY; GLOMERULOSCLEROSIS; HISTOLOGY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY DISEASE; KIDNEY HYPERTROPHY; KIDNEY PROXIMAL TUBULE; MALE; MESANGIOLYSIS; MESANGIUM CELL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TISSUE INJURY;

ALBUMINURIA; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; AUTOPHAGY; BLOOD GLUCOSE; BLOOD PRESSURE; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DISEASE PROGRESSION; ENDOPLASMIC RETICULUM STRESS; IMMUNOHISTOCHEMISTRY; KIDNEY; MICE; MICE, INBRED NOD; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 84901367130     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-1279     Document Type: Article

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