Bile acid flux is necessary for normal liver regeneration

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Naugler, Willscott E ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CARBON TETRACHLORIDE; CHOLESTEROL 7ALPHA MONOOXYGENASE; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 15; PROTEIN C JUN; RNA; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AP 1 GENE; ARTICLE; BILE DUCT FISTULA; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DUODENUM; ENTEROHEPATIC CIRCULATION; GENE EXPRESSION REGULATION; INTOXICATION; KNOCKOUT MOUSE; LIVER CELL; LIVER INJURY; LIVER REGENERATION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE C JUN; PARTIAL HEPATECTOMY; POLYMERASE CHAIN REACTION; PORTAL VEIN BLOOD FLOW; RAT; RNA SEQUENCE; SIGNAL TRANSDUCTION; SYSTEMIC CIRCULATION; ANIMAL; LIVER; LIVER RESECTION; METABOLISM; PHYSIOLOGY; SURGERY;

ANIMALS; BILE ACIDS AND SALTS; HEPATECTOMY; LIVER; LIVER REGENERATION; MALE; MICE; MICE, KNOCKOUT; RATS; TRANSCRIPTION FACTOR AP-1;

EID: 84901344620     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097426     Document Type: Article

References (41)

1. Higgins G, Anderson R (1931) Restoration of liver of white rat following partial surgical removal. Archives of Pathology 12: 186-202.
2. Fausto N, Campbell JS, Riehle KJ (2006) Liver regeneration. Hepatology 43: S45-53.
3. Taub R (2004) Liver regeneration: from myth to mechanism. Nat Rev Mol Cell Biol 5: 836-847.
4. Michalopoulos GK (2010) Liver regeneration after partial hepatectomy: critical analysis of mechanistic dilemmas. Am J Pathol 176: 2-13.
5. Apte U, Gkretsi V, Bowen WC, Mars WM, Luo JH, et al. (2009) Enhanced liver regeneration following changes induced by hepatocyte-specific genetic ablation of integrin-linked kinase. Hepatology 50: 844-851.
6. Huang J, Rudnick DA (2013) Elucidating the Metabolic Regulation of Liver Regeneration. Am J Pathol.
7. Malato Y, Naqvi S, Schurmann N, Ng R, Wang B, et al. (2011) Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration. J Clin Invest 121: 4850-4860.
8. Iyomasa S, Terasaki M, Kuriki H, Nimura Y, Shionoya S, et al. (1992) Decrease in regeneration capacity of rat liver after external biliary drainage. Eur Surg Res 24: 265-272.
9. Suzuki H, Iyomasa S, Nimura Y, Yoshida S (1994) Internal biliary drainage, unlike external drainage, does not suppress the regeneration of cholestatic rat liver after partial hepatectomy. Hepatology 20: 1318-1322. (Pubitemid 24323583)
10. Dong X, Zhao H, Ma X, Wang S (2010) Reduction in bile acid pool causes delayed liver regeneration accompanied by down-regulated expression of FXR and c-Jun mRNA in rats. J Huazhong Univ Sci Technolog Med Sci 30: 55-60.
11. Otao R, Beppu T, Isiko T, Mima K, Okabe H, et al. (2012) External biliary drainage and liver regeneration after major hepatectomy. Br J Surg 99: 1569-1574.
12. Sinal CJ, Tohkin M, Miyata M, Ward JM, Lambert G, et al. (2000) Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell 102: 731-744.
13. Huang W, Ma K, Zhang J, Qatanani M, Cuvillier J, et al. (2006) Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration. Science 312: 233-236.
14. Zhang L, Wang YD, Chen WD, Wang X, Lou G, et al. (2012) Promotion of liver regeneration/repair by farnesoid X receptor in both liver and intestine in mice. Hepatology 56: 2336-2343.
15. Uriarte I, Fernandez-Barrena MG, Monte MJ, Latasa MU, Chang HC, et al. (2013) Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice. Gut.
16. Pean N, Doignon I, Garcin I, Besnard A, Julien B, et al. (2013) The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice. Hepatology 58: 1451-1460.
17. Dawson PA, Haywood J, Craddock AL, Wilson M, Tietjen M, et al. (2003) Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice. J Biol Chem 278: 33920-33927. (Pubitemid 37553226)
18. Kuipers F, Havinga R, Bosschieter H, Toorop GP, Hindriks FR, et al. (1985) Enterohepatic circulation in the rat. Gastroenterology 88: 403-411. (Pubitemid 15194702)
19. Greene AK, Puder M (2003) Partial hepatectomy in the mouse: technique and perioperative management. J Invest Surg 16: 99-102. (Pubitemid 36609041)
20. Pandak WM, Li YC, Chiang JY, Studer EJ, Gurley EC, et al. (1991) Regulation of cholesterol 7 alpha-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat. J Biol Chem 266: 3416-3421. (Pubitemid 21909229)
21. Inagaki T, Choi M, Moschetta A, Peng L, Cummins CL, et al. (2005) Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis. Cell Metab 2: 217-225.
22. Hardison WG, Hatoff DE, Miyai K, Weiner RG (1981) Nature of bile acid maximum secretory rate in the rat. Am J Physiol 241: G337-343.
23. Doignon I, Julien B, Serriere-Lanneau V, Garcin I, Alonso G, et al. (2011) Immediate neuroendocrine signaling after partial hepatectomy through acute portal hyperpressure and cholestasis. J Hepatol 54: 481-488.
24. Gerloff T, Geier A, Stieger B, Hagenbuch B, Meier PJ, et al. (1999) Differential expression of basolateral and canalicular organic anion transporters during regeneration of rat liver. Gastroenterology 117: 1408-1415.
25. Tsuda H, Wada S, Masui T, Inui M, Ito N, et al. (1990) Comparative sequential changes in serum and biliary levels of bile acid components after a single dose of D-galactosamine or partial hepatectomy in the rat. Liver 10: 28-34. (Pubitemid 20109995)
26. Borowiak M, Garratt AN, Wustefeld T, Strehle M, Trautwein C, et al. (2004) Met provides essential signals for liver regeneration. Proc Natl Acad Sci U S A 101: 10608-10613. (Pubitemid 38955789)
27. Huh CG, Factor VM, Sanchez A, Uchida K, Conner EA, et al. (2004) Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair. Proc Natl Acad Sci U S A 101: 4477-4482. (Pubitemid 38437436)
28. Paranjpe S, Bowen WC, Bell AW, Nejak-Bowen K, Luo JH, et al. (2007) Cell cycle effects resulting from inhibition of hepatocyte growth factor and its receptor c-Met in regenerating rat livers by RNA interference. Hepatology.
29. Campbell JS, Riehle KJ, Brooling JT, Bauer RL, Mitchell C, et al. (2006) Proinflammatory cytokine production in liver regeneration is Myd88-dependent, but independent of Cd14, Tlr2, and Tlr4. J Immunol 176: 2522-2528. (Pubitemid 43201703)
30. Schwabe RF, Bradham CA, Uehara T, Hatano E, Bennett BL, et al. (2003) c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration. Hepatology 37: 824-832. (Pubitemid 36397393)
31. Diehl AM, Yin M, Fleckenstein J, Yang SQ, Lin HZ, et al. (1994) Tumor necrosis factor-alpha induces c-jun during the regenerative response to liver injury. Am J Physiol 267: G552-561.
32. Gupta S, Stravitz RT, Dent P, Hylemon PB (2001) Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway. J Biol Chem 276: 15816-15822.
33. Graf D, Kurz AK, Fischer R, Reinehr R, Haussinger D (2002) Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner. Gastroenterology 122: 1411-1427. (Pubitemid 34465183)
34. Camargo FD, Gokhale S, Johnnidis JB, Fu D, Bell GW, et al. (2007) YAP1 increases organ size and expands undifferentiated progenitor cells. Curr Biol 17: 2054-2060. (Pubitemid 350180465)
35. Dong J, Feldmann G, Huang J, Wu S, Zhang N, et al. (2007) Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell 130: 1120-1133. (Pubitemid 47410268)
36. Moolten FL, Bucher NL (1967) Regeneration of rat liver: transfer of humoral agent by cross circulation. Science 158: 272-274.
37. Michalopoulos GK (2013) Principles of liver regeneration and growth homeostasis. Compr Physiol 3: 485-513.
38. Wuestefeld T, Pesic M, Rudalska R, Dauch D, Longerich T, et al. (2013) A Direct In Vivo RNAi Screen Identifies MKK4 as a Key Regulator of Liver Regeneration. Cell 153: 389-401.
39. Wang L, Lee YK, Bundman D, Han Y, Thevananther S, et al. (2002) Redundant pathways for negative feedback regulation of bile acid production. Dev Cell 2: 721-731. (Pubitemid 34650069)
40. Yu C, Wang F, Jin C, Huang X, McKeehan WL (2005) Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids. J Biol Chem 280: 17707-17714. (Pubitemid 41389008)
41. Zhang L, Huang X, Meng Z, Dong B, Shiah S, et al. (2009) Significance and mechanism of CYP7a1 gene regulation during the acute phase of liver regeneration. Mol Endocrinol 23: 137-145.