Hypoxia-mediated mechanism of MUC5AC production in human nasal epithelia and its implication in rhinosinusitis

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Kim, Yoon Ju ^a   Cho, Hyung Ju ^a   Shin, Woo Chul ^b   Song, Hyun Ah ^a   Yoon, Joo Heon ^a   Kim, Chang Hoon ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Hana ENT Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; MUCIN 5AC; HIF1A PROTEIN, HUMAN; LUCIFERASE; MUC5AC PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DOWN REGULATION; EPITHELIUM CELL; GENE CONTROL; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; MUCUS SECRETION; NOSE MUCOSA; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN EXPRESSION; RHINOSINUSITIS; SIGNAL TRANSDUCTION; ANOXIA; CHROMATIN IMMUNOPRECIPITATION; COMPLICATION; GEL MOBILITY SHIFT ASSAY; GENETICS; METABOLISM; MUCUS; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETION (PROCESS); SINUSITIS; TUMOR CELL LINE; WESTERN BLOTTING;

ANOXIA; BLOTTING, WESTERN; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LUCIFERASES; MUCIN 5AC; MUCUS; NASAL MUCOSA; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SINUSITIS;

EID: 84901326682     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0098136     Document Type: Article

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