Vanin-1 is a key activator for hepatic gluconeogenesis

Diabetes

Volumn 63, Issue 6, 2014, Pages 2073-2085

  Chen, Siyu ^a   Zhang, Wenxiang ^a   Tang, Chunqi ^a   Tang, Xiaoli ^a   Liu, Li ^b   Liu, Chang ^a  

^a NANJING NORMAL UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN KINASE B; REGULATOR PROTEIN; UNCLASSIFIED DRUG; VANIN 1 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; DIABETES MELLITUS; DIET RESTRICTION; ENZYME REGULATION; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; GLUCONEOGENESIS; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; HYPERGLYCEMIA; INSULIN RESISTANCE; LIVER METABOLISM; LOSS OF FUNCTION MUTATION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

AMIDOHYDROLASES; ANIMALS; CELLS, CULTURED; FEMALE; GLUCONEOGENESIS; GPI-LINKED PROTEINS; HEPATOCYTE NUCLEAR FACTOR 4; HEPATOCYTES; HUMANS; HYPERGLYCEMIA; LIVER; MALE; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; PPAR GAMMA; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84901314131     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-0788     Document Type: Article

References (50)

1. Pilkis SJ, Granner DK. Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis. Annu Rev Physiol 1992;54:885-909
2. Nordlie RC, Foster JD, Lange AJ. Regulation of glucose production by the liver. Annu Rev Nutr 1999;19:379-406
3. Sutherland C, O'Brien RM, Granner DK. Phosphatidylinositol 3-kinase, but not p70/p85 ribosomal S6 protein kinase, is required for the regulation of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by insulin. Dissociation of signaling pathways for insulin and phorbol ester regulation of PEPCK gene expression. J Biol Chem 1995;270:15501-15506
4. Biddinger SB, Kahn CR. From mice to men: insights into the insulin resistance syndromes. Annu Rev Physiol 2006;68:123-158
5. Firth RG, Bell PM, Marsh HM, Hansen I, Rizza RA. Postprandial hyperglycemia in patients with noninsulin-dependent diabetes mellitus. Role of hepatic and extrahepatic tissues. J Clin Invest 1986;77:1525-1532
6. Liu C, Lin JD. PGC-1 coactivators in the control of energy metabolism. Acta Biochim Biophys Sin (Shanghai) 2011;43:248-257
7. Herzig S, Long F, Jhala US, et al. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature 2001;413:179-183
8. Koo SH, Satoh H, Herzig S, et al. PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nat Med 2004;10:530-534
9. Yoon JC, Puigserver P, Chen G, et al. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 2001;413:131-138
10. Puigserver P, Spiegelman BM. Peroxisome proliferator-activated receptorgamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocr Rev 2003;24:78-90 (Pubitemid 36223280)
11. Pitari G, Malergue F, Martin F, et al. Pantetheinase activity of membranebound Vanin-1: lack of free cysteamine in tissues of Vanin-1 deficient mice. FEBS Lett 2000;483:149-154
12. Maras B, Barra D, Duprè S, Pitari G. Is pantetheinase the actual identity of mouse and human vanin-1 proteins? FEBS Lett 1999;461:149-152
13. Daugherty M, Polanuyer B, Farrell M, et al. Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics. J Biol Chem 2002;277:21431-21439 (Pubitemid 34952284)
14. Hayes JD, McLellan LI. Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress. Free Radic Res 1999;31:273-300 (Pubitemid 29452854)
15. Berruyer C, Martin FM, Castellano R, et al. Vanin-1-/- mice exhibit a glutathionemediated tissue resistance to oxidative stress. Mol Cell Biol 2004;24:7214-7224 (Pubitemid 39014447)
16. Martin F, Penet MF, Malergue F, et al. Vanin-1(-/-) mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher glutathione stores. J Clin Invest 2004;113:591-597 (Pubitemid 38542508)
17. Roisin-Bouffay C, Castellano R, Valéro R, Chasson L, Galland F, Naquet P. Mouse vanin-1 is cytoprotective for islet beta cells and regulates the development of type 1 diabetes. Diabetologia 2008;51:1192-1201
18. Rakhshandehroo M, Knoch B, Müller M, Kersten S. Peroxisome proliferatoractivated receptor alpha target genes. PPAR Res 2010;pii:612089
19. Rommelaere S, Millet V, Gensollen T, et al. PPARalpha regulates the production of serum Vanin-1 by liver. FEBS Lett 2013;587:3742-3748
20. Fugmann T, Borgia B, Révész C, et al. Proteomic identification of vanin-1 as a marker of kidney damage in a rat model of type 1 diabetic nephropathy. Kidney Int 2011;80:272-281
21. Huang H, Dong X, Kang MX, et al. Novel blood biomarkers of pancreatic cancer-associated diabetes mellitus identified by peripheral blood-based gene expression profiles. Am J Gastroenterol 2010;105:1661-1669
22. Lee YS, Li P, Huh JY, et al. Inflammation is necessary for long-term but not short-term high-fat diet-induced insulin resistance. Diabetes 2011;60:2474-2483
23. Ueda J, Saito H, Watanabe H, Evers BM. Novel and quantitative DNA dotblotting method for assessment of in vivo proliferation. Am J Physiol Gastrointest Liver Physiol 2005;288:G842-G847 (Pubitemid 40388196)
24. Ruan BH, Cole DC, Wu P, et al. A fluorescent assay suitable for inhibitor screening and vanin tissue quantification. Anal Biochem 2010;399:284-292
25. Berruyer C, Pouyet L, Millet V, et al. Vanin-1 licenses inflammatory mediator production by gut epithelial cells and controls colitis by antagonizing peroxisome proliferator-activated receptor gamma activity. J Exp Med 2006;203:2817-2827 (Pubitemid 46026160)
26. Duan SZ, Usher MG, Foley EL 4th, Milstone DS, Brosius FC 3rd, Mortensen RM. Sex dimorphic actions of rosiglitazone in generalised peroxisome proliferatoractivated receptor-gamma (PPAR-gamma)-deficient mice. Diabetologia 2010;53: 1493-1505
27. Kim HI, Ahn YH. Role of peroxisome proliferator-activated receptor-gamma in the glucose-sensing apparatus of liver and beta-cells. Diabetes 2004;53 (Suppl. 1):S60-S65
28. Fang B, Mane-Padros D, Bolotin E, Jiang T, Sladek FM. Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors. Nucleic Acids Res 2012;40:5343-5356
29. Min-Oo G, Fortin A, Pitari G, Tam M, Stevenson MM, Gros P. Complex genetic control of susceptibility to malaria: positional cloning of the Char9 locus. J Exp Med 2007;204:511-524 (Pubitemid 46457075)
30. Jansen PA, Kamsteeg M, Rodijk-Olthuis D, et al. Expression of the vanin gene family in normal and inflamed human skin: induction by proinflammatory cytokines. J Invest Dermatol 2009;129:2167-2174
31. Pouyet L, Roisin-Bouffay C, Clément A, et al. Epithelial vanin-1 controls inflammation-driven carcinogenesis in the colitis-associated colon cancer model. Inflamm Bowel Dis 2010;16:96-104
32. Dammanahalli KJ, Stevens S, Terkeltaub R. Vanin-1 pantetheinase drives smooth muscle cell activation in post-arterial injury neointimal hyperplasia. PLoS ONE 2012;7:e39106
33. Schoonjans K, Staels B, Auwerx J. The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation. Biochim Biophys Acta 1996;1302:93-109 (Pubitemid 26247079)
34. Lentile R, Campisi A, Raciti G, et al. Cystamine inhibits transglutaminase and caspase-3 cleavage in glutamate-exposed astroglial cells. J Neurosci Res 2003;74:52-59 (Pubitemid 37176666)
35. Karpuj MV, Becher MW, Springer JE, et al. Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine. Nat Med 2002;8:143-149 (Pubitemid 34155125)
36. Bhargava P, Lee CH. Role and function of macrophages in the metabolic syndrome. Biochem J 2012;442:253-262
37. Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006;444: 860-867 (Pubitemid 46024993)
38. Osborn O, Olefsky JM. The cellular and signaling networks linking the immune system and metabolism in disease. Nat Med 2012;18:363-374
39. Issad T, Kuo M. O-GlcNAc modification of transcription factors, glucose sensing and glucotoxicity. Trends Endocrinol Metab 2008;19:380-389
40. Lamia KA, Storch KF, Weitz CJ. Physiological significance of a peripheral tissue circadian clock. Proc Natl Acad Sci U S A 2008;105:15172-15177
41. Lin J, Wu PH, Tarr PT, et al. Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell 2004;119:121-135 (Pubitemid 39349325)
42. Maachi M, Piéroni L, Bruckert E, et al. Systemic low-grade inflammation is related to both circulating and adipose tissue TNFalpha, leptin and IL-6 levels in obese women. Int J Obes Relat Metab Disord 2004;28:993-997 (Pubitemid 38998704)
43. Kalofoutis C, Piperi C, Zisaki A, et al. Differences in expression of cardiovascular risk factors among type 2 diabetes mellitus patients of different age. Ann N Y Acad Sci 2006;1084:166-177 (Pubitemid 47091936)
44. Endo M, Masaki T, Seike M, Yoshimatsu H. TNF-alpha induces hepatic steatosis in mice by enhancing gene expression of sterol regulatory element binding protein-1c (SREBP-1c). Exp Biol Med (Maywood) 2007;232:614-621 (Pubitemid 46683386)
45. Feillet-Coudray C, Rock E, Coudray C, et al. Lipid peroxidation and antioxidant status in experimental diabetes. Clin Chim Acta 1999;284:31-43 (Pubitemid 29324863)
46. Whiteman EL, Cho H, Birnbaum MJ. Role of Akt/protein kinase B in metabolism. Trends Endocrinol Metab 2002;13:444-451 (Pubitemid 36733939)
47. Duplain H, Sartori C, Dessen P, et al. Stimulation of peroxynitrite catalysis improves insulin sensitivity in high fat diet-fed mice. J Physiol 2008;586:4011-4016
48. Strahl BD, Allis CD. The language of covalent histone modifications. Nature 2000;403:41-45 (Pubitemid 30038513)
49. Berger SL. An embarrassment of niches: the many covalent modifications of histones in transcriptional regulation. Oncogene 2001;20:3007- 3013 (Pubitemid 32553554)
50. Jansen PA, van Diepen JA, Ritzen B, et al. Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease. ACS Chem Biol 2013;8:530-534