Somatic hypermutation at A/T-Rich oligonucleotide substrates shows different strand polarities in Ung-deficient or -proficient backgrounds

Molecular and Cellular Biology

Volumn 34, Issue 12, 2014, Pages 2176-2187

  Zivojnovic, Marija ^a   Delbos, Frédéric ^a,c   Zubani, Giulia Girelli ^a   Julé, Amélie ^a,d   Alcais, Alexandre ^b   Weill, Jean Claude ^a   Reynaud, Claude Agnès ^a   Storck, Sébastien ^a  

^a INSTITUT NECKER ENFANTS MALADES   (France)

^b IMAGINE INSTITUTE   (France)

^c Centre National de la Recherche Scientifique   (France)

^d INSTITUT COCHIN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE ETA; OLIGONUCLEOTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AT RICH SEQUENCE; CONTROLLED STUDY; DNA FLANKING REGION; ENZYME SYNTHESIS; GENE DELETION; GENE INSERTION; GENE LOCUS; IMMUNOGLOBULIN HEAVY CHAIN GENE; MISMATCH REPAIR; MOUSE; MUTATION RATE; NONHUMAN; NUCLEOTIDE SEQUENCE; PMS2 GENE; PRIORITY JOURNAL; SOMATIC HYPERMUTATION; TRANSGENE; UNG GENE;

ADENOSINE TRIPHOSPHATASES; AMINO ACID MOTIFS; ANIMALS; AT RICH SEQUENCE; BASE SEQUENCE; DNA; DNA GLYCOSYLASES; DNA MISMATCH REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; GENE KNOCK-IN TECHNIQUES; GENETIC LOCI; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; MUTATION RATE; OLIGONUCLEOTIDES; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; SUBSTRATE SPECIFICITY; TRANSGENES; URACIL-DNA GLYCOSIDASE;

EID: 84901308558     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01452-13     Document Type: Article

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