Downregulation of miR-124 in MPTP-treated mouse model of Parkinson's disease and MPP iodide-treated MN9D cells modulates the expression of the calpain/cdk5 pathway proteins

Neuroscience

Volumn 272, Issue , 2014, Pages 167-179

  Kanagaraj, N ^a   Beiping, H ^a   Dheen, S T ^a   Tay, S S W ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

MicroRNA; MiR 124; MN9D cells; MPTP induced mouse model of Parkinson's disease; Parkinson's disease

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CALPAIN 1; CALPAIN 2; CYCLIN DEPENDENT KINASE 5; HYDROGEN PEROXIDE; MICRORNA; MICRORNA 124; PROTEIN P25; PROTEIN P35; REACTIVE OXYGEN METABOLITE; CALPAIN; MIRN124 MICRORNA, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOWN REGULATION; IN VITRO STUDY; MALE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN INTERACTION; SUBSTANTIA NIGRA PARS COMPACTA; TRANSCRIPTION REGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL DEATH; DISEASE MODEL; DRUG EFFECTS; METABOLISM; SUBSTANTIA NIGRA;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; CALPAIN; CELL DEATH; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 5; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; DOWN-REGULATION; HYDROGEN PEROXIDE; MALE; MICE, INBRED C57BL; MICRORNAS; PARKINSON DISEASE; SUBSTANTIA NIGRA;

EID: 84901291992     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.04.039     Document Type: Article

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