메뉴 건너뛰기




Volumn 78, Issue 6, 2014, Pages 1283-1289

Insights into the activation and inhibition of angiotensin II type 1 receptor in the mechanically loaded heart

Author keywords

Angiotensin II type 1 receptor; Cardiomyocyte hypertrophy; Inverse agonism; Mechanical stress

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ATRIAL NATRIURETIC FACTOR; AZILSARTAN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CANDESARTAN; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIN 1; EPROSARTAN; GUANINE NUCLEOTIDE BINDING PROTEIN; HISTONE DEACETYLASE; IRBESARTAN; ISOPRENALINE; LIM PROTEIN; LOSARTAN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE 7; OLMESARTAN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE TYK2; SOMATOMEDIN C; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TELMISARTAN; UNINDEXED DRUG; VALSARTAN; ANGIOTENSIN II; RETINA S ANTIGEN;

EID: 84901290590     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-14-0470     Document Type: Review
Times cited : (31)

References (60)
  • 1
    • 2942751868 scopus 로고    scopus 로고
    • Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II
    • Zou Y, Akazawa H, Qin Y, Sano M, Takano H, Minamino T, et al. Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. Nat Cell Biol 2004; 6: 499-506.
    • (2004) Nat Cell Biol , vol.6 , pp. 499-506
    • Zou, Y.1    Akazawa, H.2    Qin, Y.3    Sano, M.4    Takano, H.5    Minamino, T.6
  • 2
    • 84888122574 scopus 로고    scopus 로고
    • Solving the cardiac hypertrophy riddle: The angiotensin II-mechanical stress connection
    • Zablocki D, Sadoshima J. Solving the cardiac hypertrophy riddle: The angiotensin II-mechanical stress connection. Circ Res 2013; 113: 1192-1195.
    • (2013) Circ Res , vol.113 , pp. 1192-1195
    • Zablocki, D.1    Sadoshima, J.2
  • 3
    • 0033824138 scopus 로고    scopus 로고
    • International union of pharmacology. XXIII: The angiotensin II receptors
    • de Gasparo M, Catt KJ, Inagami T, Wright JW, Unger T. International union of pharmacology. XXIII: The angiotensin II receptors. Pharmacol Rev 2000; 52: 415-472.
    • (2000) Pharmacol Rev , vol.52 , pp. 415-472
    • de Gasparo, M.1    Catt, K.J.2    Inagami, T.3    Wright, J.W.4    Unger, T.5
  • 4
    • 27644453447 scopus 로고    scopus 로고
    • Addition of an angiotensin receptor blocker to full-dose ACE-inhibition: Controversial or common sense?
    • van de Wal RM, van Veldhuisen DJ, van Gilst WH, Voors AA. Addition of an angiotensin receptor blocker to full-dose ACE-inhibition: Controversial or common sense? Eur Heart J 2005; 26: 2361-2367.
    • (2005) Eur Heart J , vol.26 , pp. 2361-2367
    • van de Wal, R.M.1    van Veldhuisen, D.J.2    van Gilst, W.H.3    Voors, A.A.4
  • 5
    • 84901340418 scopus 로고    scopus 로고
    • Mechanical stress induces cardiomyocyte hypertrophy through agonist-independent activation of angiotensin II type 1 receptor
    • In: Kamkin A, Kiseleva I, editors, Dordrecht, the Netherlands: Springer
    • Akazawa H, Komuro I. Mechanical stress induces cardiomyocyte hypertrophy through agonist-independent activation of angiotensin II type 1 receptor. In: Kamkin A, Kiseleva I, editors. Mechanosensitivity of the heart. Dordrecht, the Netherlands: Springer, 2010; 83-95.
    • (2010) Mechanosensitivity of the heart , pp. 83-95
    • Akazawa, H.1    Komuro, I.2
  • 6
    • 38949137039 scopus 로고    scopus 로고
    • Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation
    • Yasuda N, Miura S, Akazawa H, Tanaka T, Qin Y, Kiya Y, et al. Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation. EMBO Rep 2008; 9: 179-186.
    • (2008) EMBO Rep , vol.9 , pp. 179-186
    • Yasuda, N.1    Miura, S.2    Akazawa, H.3    Tanaka, T.4    Qin, Y.5    Kiya, Y.6
  • 7
    • 84878647353 scopus 로고    scopus 로고
    • Recent progress in molecular mechanisms of angiotensin II type 1 and 2 receptors
    • Miura S, Imaizumi S, Saku K. Recent progress in molecular mechanisms of angiotensin II type 1 and 2 receptors. Curr Pharm Des 2013; 19: 2981-2987.
    • (2013) Curr Pharm Des , vol.19 , pp. 2981-2987
    • Miura, S.1    Imaizumi, S.2    Saku, K.3
  • 9
    • 84904671848 scopus 로고    scopus 로고
    • Novel role of mechanosensitive AT1B receptors in myogenic vasoconstriction
    • October 8, doi: 10. 1007/s00424-013-1372-3
    • Blodow S, Schneider H, Storch U, Wizemann R, Forst AL, Gudermann T, et al. Novel role of mechanosensitive AT1B receptors in myogenic vasoconstriction. Pflugers Arch 2013 October 8, doi: 10. 1007/s00424-013-1372-3.
    • (2013) Pflugers Arch
    • Blodow, S.1    Schneider, H.2    Storch, U.3    Wizemann, R.4    Forst, A.L.5    Gudermann, T.6
  • 10
    • 0027722248 scopus 로고
    • Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro
    • Sadoshima JI, Xu Y, Slayter HS, Izumo S. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell 1993; 75: 977-984.
    • (1993) Cell , vol.75 , pp. 977-984
    • Sadoshima, J.I.1    Xu, Y.2    Slayter, H.S.3    Izumo, S.4
  • 11
    • 0026794976 scopus 로고
    • Intracardiac detection of angiotensinogen and renin: A localized reninangiotensin system in neonatal rat heart
    • Dostal DE, Rothblum KN, Chernin MI, Cooper GR, Baker KM. Intracardiac detection of angiotensinogen and renin: A localized reninangiotensin system in neonatal rat heart. Am J Physiol 1992; 263: C838-C850.
    • (1992) Am J Physiol , vol.263
    • Dostal, D.E.1    Rothblum, K.N.2    Chernin, M.I.3    Cooper, G.R.4    Baker, K.M.5
  • 12
    • 0033635110 scopus 로고    scopus 로고
    • Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells
    • Touyz RM, Schiffrin EL. Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Pharmacol Rev 2000; 52: 639-672.
    • (2000) Pharmacol Rev , vol.52 , pp. 639-672
    • Touyz, R.M.1    Schiffrin, E.L.2
  • 14
    • 0029117515 scopus 로고
    • Angiotensin II partly mediates mechanical stress-induced cardiac hypertrophy
    • Yamazaki T, Komuro I, Kudoh S, Zou Y, Shiojima I, Mizuno T, et al. Angiotensin II partly mediates mechanical stress-induced cardiac hypertrophy. Circ Res 1995; 77: 258-265.
    • (1995) Circ Res , vol.77 , pp. 258-265
    • Yamazaki, T.1    Komuro, I.2    Kudoh, S.3    Zou, Y.4    Shiojima, I.5    Mizuno, T.6
  • 15
    • 0029873040 scopus 로고    scopus 로고
    • Passive load and angiotensin II evoke differential responses of gene expression and protein synthesis in cardiac myocytes
    • Kent RL, McDermott PJ. Passive load and angiotensin II evoke differential responses of gene expression and protein synthesis in cardiac myocytes. Circ Res 1996; 78: 829-838.
    • (1996) Circ Res , vol.78 , pp. 829-838
    • Kent, R.L.1    McDermott, P.J.2
  • 16
    • 0033597946 scopus 로고    scopus 로고
    • Mechanical stretch and angiotensin II differentially upregulate the renin-angiotensin system in cardiac myocytes in vitro
    • Malhotra R, Sadoshima J, Brosius FC, Izumo S. Mechanical stretch and angiotensin II differentially upregulate the renin-angiotensin system in cardiac myocytes in vitro. Circ Res 1999; 85: 137-146.
    • (1999) Circ Res , vol.85 , pp. 137-146
    • Malhotra, R.1    Sadoshima, J.2    Brosius, F.C.3    Izumo, S.4
  • 17
    • 0032546640 scopus 로고    scopus 로고
    • Pressure overload induces cardiac hypertrophy in angiotensin II type 1A receptor knockout mice
    • Harada K, Komuro I, Shiojima I, Hayashi D, Kudoh S, Mizuno T, et al. Pressure overload induces cardiac hypertrophy in angiotensin II type 1A receptor knockout mice. Circulation 1998; 97: 1952-1959.
    • (1998) Circulation , vol.97 , pp. 1952-1959
    • Harada, K.1    Komuro, I.2    Shiojima, I.3    Hayashi, D.4    Kudoh, S.5    Mizuno, T.6
  • 18
    • 0033548623 scopus 로고    scopus 로고
    • Role of aromaticity of agonist switches of angiotensin II in the activation of the AT1 recep-tor
    • Miura S, Feng YH, Husain A, Karnik SS. Role of aromaticity of agonist switches of angiotensin II in the activation of the AT1 recep-tor. J Biol Chem 1999; 274: 7103-7110.
    • (1999) J Biol Chem , vol.274 , pp. 7103-7110
    • Miura, S.1    Feng, Y.H.2    Husain, A.3    Karnik, S.S.4
  • 19
    • 79960355012 scopus 로고    scopus 로고
    • G protein-dependent and G protein-independent signaling pathways and their impact on cardiac function
    • Tilley DG. G protein-dependent and G protein-independent signaling pathways and their impact on cardiac function. Circ Res 2011; 109: 217-230.
    • (2011) Circ Res , vol.109 , pp. 217-230
    • Tilley, D.G.1
  • 20
    • 33748323383 scopus 로고    scopus 로고
    • Regulation of cardiac hypertrophy by intracellular signalling pathways
    • Heineke J, Molkentin JD. Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 2006; 7: 589-600.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 589-600
    • Heineke, J.1    Molkentin, J.D.2
  • 21
    • 0032543959 scopus 로고    scopus 로고
    • Enhanced Galphaq signaling: A common pathway mediates cardiac hypertrophy and apoptotic heart failure
    • Adams JW, Sakata Y, Davis MG, Sah VP, Wang Y, Liggett SB, et al. Enhanced Galphaq signaling: A common pathway mediates cardiac hypertrophy and apoptotic heart failure. Proc Natl Acad Sci USA 1998; 95: 10140-10145.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 10140-10145
    • Adams, J.W.1    Sakata, Y.2    Davis, M.G.3    Sah, V.P.4    Wang, Y.5    Liggett, S.B.6
  • 22
    • 0032562289 scopus 로고    scopus 로고
    • Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy
    • Akhter SA, Luttrell LM, Rockman HA, Iaccarino G, Lefkowitz RJ, Koch WJ. Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. Science 1998; 280: 574-577.
    • (1998) Science , vol.280 , pp. 574-577
    • Akhter, S.A.1    Luttrell, L.M.2    Rockman, H.A.3    Iaccarino, G.4    Lefkowitz, R.J.5    Koch, W.J.6
  • 23
    • 0035166852 scopus 로고    scopus 로고
    • Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Galphaq/Galpha11 in cardiomyocytes
    • Wettschureck N, Rutten H, Zywietz A, Gehring D, Wilkie TM, Chen J, et al. Absence of pressure overload induced myocardial hypertrophy after conditional inactivation of Galphaq/Galpha11 in cardiomyocytes. Nat Med 2001; 7: 1236-1240.
    • (2001) Nat Med , vol.7 , pp. 1236-1240
    • Wettschureck, N.1    Rutten, H.2    Zywietz, A.3    Gehring, D.4    Wilkie, T.M.5    Chen, J.6
  • 24
    • 34247113814 scopus 로고    scopus 로고
    • Angiotensin II signal transduction through the AT1 receptor: Novel insights into mechanisms and pathophysiology
    • Higuchi S, Ohtsu H, Suzuki H, Shirai H, Frank GD, Eguchi S. Angiotensin II signal transduction through the AT1 receptor: Novel insights into mechanisms and pathophysiology. Clin Sci (Lond) 2007; 112: 417-428.
    • (2007) Clin Sci (Lond) , vol.112 , pp. 417-428
    • Higuchi, S.1    Ohtsu, H.2    Suzuki, H.3    Shirai, H.4    Frank, G.D.5    Eguchi, S.6
  • 25
    • 73849139311 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases as biomarkers of hypertension or cardiac pressure overload
    • Ocaranza MP, Jalil JE. Mitogen-activated protein kinases as biomarkers of hypertension or cardiac pressure overload. Hypertension 2010; 55: 23-25.
    • (2010) Hypertension , vol.55 , pp. 23-25
    • Ocaranza, M.P.1    Jalil, J.E.2
  • 26
    • 84873353766 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinase pathways in multifactorial adverse cardiac remodeling associated with metabolic syndrome
    • Asrih M, Mach F, Nencioni A, Dallegri F, Quercioli A, Montecucco F. Role of mitogen-activated protein kinase pathways in multifactorial adverse cardiac remodeling associated with metabolic syndrome. Mediators Inflamm 2013; 2013: 367245.
    • (2013) Mediators Inflamm , vol.2013 , pp. 367245
    • Asrih, M.1    Mach, F.2    Nencioni, A.3    Dallegri, F.4    Quercioli, A.5    Montecucco, F.6
  • 27
    • 77955494734 scopus 로고    scopus 로고
    • Mechanical stressevoked but angiotensin II-independent activation of angiotensin II type 1 receptor induces cardiac hypertrophy through calcineurin pathway
    • Zhou N, Li L, Wu J, Gong H, Niu Y, Sun A, et al. Mechanical stressevoked but angiotensin II-independent activation of angiotensin II type 1 receptor induces cardiac hypertrophy through calcineurin pathway. Biochem Biophys Res Commun 2010; 397: 263-269.
    • (2010) Biochem Biophys Res Commun , vol.397 , pp. 263-269
    • Zhou, N.1    Li, L.2    Wu, J.3    Gong, H.4    Niu, Y.5    Sun, A.6
  • 28
    • 83155175187 scopus 로고    scopus 로고
    • Ryanodine receptor type 2 is required for the development of pressure overloadinduced cardiac hypertrophy
    • Zou Y, Liang Y, Gong H, Zhou N, Ma H, Guan A, et al. Ryanodine receptor type 2 is required for the development of pressure overloadinduced cardiac hypertrophy. Hypertension 2011; 58: 1099-1110.
    • (2011) Hypertension , vol.58 , pp. 1099-1110
    • Zou, Y.1    Liang, Y.2    Gong, H.3    Zhou, N.4    Ma, H.5    Guan, A.6
  • 29
    • 0037088597 scopus 로고    scopus 로고
    • AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKs
    • Seta K, Nanamori M, Modrall JG, Neubig RR, Sadoshima J. AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKs. J Biol Chem 2002; 277: 9268-9277.
    • (2002) J Biol Chem , vol.277 , pp. 9268-9277
    • Seta, K.1    Nanamori, M.2    Modrall, J.G.3    Neubig, R.R.4    Sadoshima, J.5
  • 30
    • 27644468385 scopus 로고    scopus 로고
    • Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice
    • Zhai P, Yamamoto M, Galeotti J, Liu J, Masurekar M, Thaisz J, et al. Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice. J Clin Invest 2005; 115: 3045-3056.
    • (2005) J Clin Invest , vol.115 , pp. 3045-3056
    • Zhai, P.1    Yamamoto, M.2    Galeotti, J.3    Liu, J.4    Masurekar, M.5    Thaisz, J.6
  • 31
    • 84899441356 scopus 로고    scopus 로고
    • Src is required for mechanical stretch-Induced cardiomyocyte hypertrophy through angiotensin II type 1 receptor-dependent β-Arrestin2 pathways
    • doi: 92910. 91371/journal. pone. 0092926
    • Wang S, Gong H, Jiang G, Ye Y, Wu J, You J, et al. Src is required for mechanical stretch-Induced cardiomyocyte hypertrophy through angiotensin II type 1 receptor-dependent β-Arrestin2 pathways. PLoS One 2014; 9: e92926, doi: 92910. 91371/journal. pone. 0092926.
    • (2014) PLoS One , vol.9
    • Wang, S.1    Gong, H.2    Jiang, G.3    Ye, Y.4    Wu, J.5    You, J.6
  • 32
    • 77953819826 scopus 로고    scopus 로고
    • Beta-Arrestin-biased agonism of the angiotensin receptor induced by mechanical stress
    • Rakesh K, Yoo B, Kim IM, Salazar N, Kim KS, Rockman HA. beta-Arrestin-biased agonism of the angiotensin receptor induced by mechanical stress. Sci Signal 2010; 3: ra46.
    • (2010) Sci Signal , vol.3
    • Rakesh, K.1    Yoo, B.2    Kim, I.M.3    Salazar, N.4    Kim, K.S.5    Rockman, H.A.6
  • 33
    • 33750802401 scopus 로고    scopus 로고
    • Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes
    • Rajagopal K, Whalen EJ, Violin JD, Stiber JA, Rosenberg PB, Premont RT, et al. Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes. Proc Natl Acad Sci USA 2006; 103: 16284-16289.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 16284-16289
    • Rajagopal, K.1    Whalen, E.J.2    Violin, J.D.3    Stiber, J.A.4    Rosenberg, P.B.5    Premont, R.T.6
  • 34
    • 33845317252 scopus 로고    scopus 로고
    • ANG II-induced cell proliferation is dually mediated by c-Src/Yes/Fyn-regulated ERK1/2 activation in the cytoplasm and PKCζ-controlled ERK1/2 activity within the nucleus
    • Godeny MD, Sayeski PP. ANG II-induced cell proliferation is dually mediated by c-Src/Yes/Fyn-regulated ERK1/2 activation in the cytoplasm and PKCζ-controlled ERK1/2 activity within the nucleus. Am J Physiol Cell Physiol 2006; 291: C1297-C1307.
    • (2006) Am J Physiol Cell Physiol , vol.291
    • Godeny, M.D.1    Sayeski, P.P.2
  • 35
    • 66449134043 scopus 로고    scopus 로고
    • Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor
    • Kim J, Ahn S, Rajagopal K, Lefkowitz RJ. Independent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptor. J Biol Chem 2009; 284: 11953-11962.
    • (2009) J Biol Chem , vol.284 , pp. 11953-11962
    • Kim, J.1    Ahn, S.2    Rajagopal, K.3    Lefkowitz, R.J.4
  • 36
    • 79956270842 scopus 로고    scopus 로고
    • Functional relevance of biased signaling at the angiotensin II type 1 receptor
    • Tilley DG. Functional relevance of biased signaling at the angiotensin II type 1 receptor. Endocr Metab Immune Disord Drug Targets 2011; 11: 99-111.
    • (2011) Endocr Metab Immune Disord Drug Targets , vol.11 , pp. 99-111
    • Tilley, D.G.1
  • 38
    • 63849322493 scopus 로고    scopus 로고
    • Role of phosphoinositide 3-kinases in regulating cardiac function
    • Pretorius L, Owen KL, McMullen JR. Role of phosphoinositide 3-kinases in regulating cardiac function. Front Biosci (Landmark Ed) 2009; 14: 2221-2229.
    • (2009) Front Biosci (Landmark Ed) , vol.14 , pp. 2221-2229
    • Pretorius, L.1    Owen, K.L.2    McMullen, J.R.3
  • 40
    • 84869150485 scopus 로고    scopus 로고
    • Comparison between adenosine and isoflurane for assessing the coronary flow reserve in mouse models of left ventricular pressure and volume overload
    • You J, Wu J, Ge J, Zou Y. Comparison between adenosine and isoflurane for assessing the coronary flow reserve in mouse models of left ventricular pressure and volume overload. Am J Physiol Heart Circ Physiol 2012; 303: H1199-H1207.
    • (2012) Am J Physiol Heart Circ Physiol , vol.303
    • You, J.1    Wu, J.2    Ge, J.3    Zou, Y.4
  • 41
    • 0036200340 scopus 로고    scopus 로고
    • Tissue Angiotensin-converting enzyme activity plays an important role in pressure overloadinduced cardiac fibrosis in rats
    • Kurosawa Y, Katoh M, Doi H, Narita H. Tissue Angiotensin-converting enzyme activity plays an important role in pressure overloadinduced cardiac fibrosis in rats. J Cardiovasc Pharmacol 2002; 39: 600-609.
    • (2002) J Cardiovasc Pharmacol , vol.39 , pp. 600-609
    • Kurosawa, Y.1    Katoh, M.2    Doi, H.3    Narita, H.4
  • 42
    • 0034681187 scopus 로고    scopus 로고
    • Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling
    • Paradis P, Dali-Youcef N, Paradis FW, Thibault G, Nemer M. Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling. Proc Natl Acad Sci USA 2000; 97: 931-936.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 931-936
    • Paradis, P.1    Dali-Youcef, N.2    Paradis, F.W.3    Thibault, G.4    Nemer, M.5
  • 43
    • 0034795437 scopus 로고    scopus 로고
    • Overexpression of the human angiotensin II type 1 receptor in the rat heart augments load induced cardiac hypertrophy
    • Hoffmann S, Krause T, van Geel PP, Willenbrock R, Pagel I, Pinto YM, et al. Overexpression of the human angiotensin II type 1 receptor in the rat heart augments load induced cardiac hypertrophy. J Mol Med (Berl) 2001; 79: 601-608.
    • (2001) J Mol Med (Berl) , vol.79 , pp. 601-608
    • Hoffmann, S.1    Krause, T.2    van Geel, P.P.3    Willenbrock, R.4    Pagel, I.5    Pinto, Y.M.6
  • 44
    • 0041408235 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: The CHARM-Added trial
    • McMurray JJ, Ostergren J, Swedberg K, Granger CB, Held P, Michelson EL, et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: The CHARM-Added trial. Lancet 2003; 362: 767-771.
    • (2003) Lancet , vol.362 , pp. 767-771
    • McMurray, J.J.1    Ostergren, J.2    Swedberg, K.3    Granger, C.B.4    Held, P.5    Michelson, E.L.6
  • 45
    • 78649875462 scopus 로고    scopus 로고
    • Comparison of angiotensin II type 1-receptor blockers to regress pressure overloadinduced cardiac hypertrophy in mice
    • Li L, Zhou N, Gong H, Wu J, Lin L, Komuro I, et al. Comparison of angiotensin II type 1-receptor blockers to regress pressure overloadinduced cardiac hypertrophy in mice. Hypertens Res 2010; 33: 1289-1297.
    • (2010) Hypertens Res , vol.33 , pp. 1289-1297
    • Li, L.1    Zhou, N.2    Gong, H.3    Wu, J.4    Lin, L.5    Komuro, I.6
  • 46
    • 0034100147 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases
    • Kim S, Iwao H. Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases. Pharmacol Rev 2000; 52: 11-34.
    • (2000) Pharmacol Rev , vol.52 , pp. 11-34
    • Kim, S.1    Iwao, H.2
  • 48
    • 84858625891 scopus 로고    scopus 로고
    • Renal sympathetic denervation suppresses de novo podocyte injury and albuminuria in rats with aortic regurgitation
    • Rafiq K, Noma T, Fujisawa Y, Ishihara Y, Arai Y, Nabi AH, et al. Renal sympathetic denervation suppresses de novo podocyte injury and albuminuria in rats with aortic regurgitation. Circulation 2012; 125: 1402-1413.
    • (2012) Circulation , vol.125 , pp. 1402-1413
    • Rafiq, K.1    Noma, T.2    Fujisawa, Y.3    Ishihara, Y.4    Arai, Y.5    Nabi, A.H.6
  • 49
    • 33747195339 scopus 로고    scopus 로고
    • Losartan attenuates phospholipase C isozyme gene expression in hypertrophied hearts due to volume overload
    • Dent MR, Aroutiounova N, Dhalla NS, Tappia PS. Losartan attenuates phospholipase C isozyme gene expression in hypertrophied hearts due to volume overload. J Cell Mol Med 2006; 10: 470-479.
    • (2006) J Cell Mol Med , vol.10 , pp. 470-479
    • Dent, M.R.1    Aroutiounova, N.2    Dhalla, N.S.3    Tappia, P.S.4
  • 50
    • 33745166297 scopus 로고    scopus 로고
    • Expression of protein kinase C isoforms in cardiac hypertrophy and heart failure due to volume overload
    • Sentex E, Wang X, Liu X, Lukas A, Dhalla NS. Expression of protein kinase C isoforms in cardiac hypertrophy and heart failure due to volume overload. Can J Physiol Pharmacol 2006; 84: 227-238.
    • (2006) Can J Physiol Pharmacol , vol.84 , pp. 227-238
    • Sentex, E.1    Wang, X.2    Liu, X.3    Lukas, A.4    Dhalla, N.S.5
  • 52
    • 76649085797 scopus 로고    scopus 로고
    • Alterations of cardiac ERK1/2 expression and activity due to volume overload were attenuated by the blockade of RAS
    • Zhang W, Elimban V, Xu YJ, Zhang M, Nijjar MS, Dhalla NS. Alterations of cardiac ERK1/2 expression and activity due to volume overload were attenuated by the blockade of RAS. J Cardiovasc Pharmacol Ther 2010; 15: 84-92.
    • (2010) J Cardiovasc Pharmacol Ther , vol.15 , pp. 84-92
    • Zhang, W.1    Elimban, V.2    Xu, Y.J.3    Zhang, M.4    Nijjar, M.S.5    Dhalla, N.S.6
  • 53
    • 34547598307 scopus 로고    scopus 로고
    • Genetic disruption of angiotensin II type 1a receptor improves long-term survival of mice with chronic severe aortic regurgitation
    • Nakanishi M, Harada M, Kishimoto I, Kuwahara K, Kawakami R, Nakagawa Y, et al. Genetic disruption of angiotensin II type 1a receptor improves long-term survival of mice with chronic severe aortic regurgitation. Circ J 2007; 71: 1310-1316.
    • (2007) Circ J , vol.71 , pp. 1310-1316
    • Nakanishi, M.1    Harada, M.2    Kishimoto, I.3    Kuwahara, K.4    Kawakami, R.5    Nakagawa, Y.6
  • 54
    • 77953654201 scopus 로고    scopus 로고
    • Comparative study of vasodilators in an animal model of chronic volume overload caused by severe aortic regurgitation
    • Plante E, Lachance D, Beaudoin J, Champetier S, Roussel E, Arsenault M, et al. Comparative study of vasodilators in an animal model of chronic volume overload caused by severe aortic regurgitation. Circ Heart Fail 2009; 2: 25-32.
    • (2009) Circ Heart Fail , vol.2 , pp. 25-32
    • Plante, E.1    Lachance, D.2    Beaudoin, J.3    Champetier, S.4    Roussel, E.5    Arsenault, M.6
  • 56
    • 84857635779 scopus 로고    scopus 로고
    • Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice
    • Yasuda N, Akazawa H, Ito K, Shimizu I, Kudo-Sakamoto Y, Yabumoto C, et al. Agonist-independent constitutive activity of angiotensin II receptor promotes cardiac remodeling in mice. Hypertension 2012; 59: 627-633.
    • (2012) Hypertension , vol.59 , pp. 627-633
    • Yasuda, N.1    Akazawa, H.2    Ito, K.3    Shimizu, I.4    Kudo-Sakamoto, Y.5    Yabumoto, C.6
  • 57
    • 70349987109 scopus 로고    scopus 로고
    • Multivalent ligand-receptor interactions elicit inverse agonist activity of AT(1) receptor blockers against stretch-induced AT(1) receptor activation
    • Qin Y, Yasuda N, Akazawa H, Ito K, Kudo Y, Liao CH, et al. Multivalent ligand-receptor interactions elicit inverse agonist activity of AT(1) receptor blockers against stretch-induced AT(1) receptor activation. Hypertens Res 2009; 32: 875-883.
    • (2009) Hypertens Res , vol.32 , pp. 875-883
    • Qin, Y.1    Yasuda, N.2    Akazawa, H.3    Ito, K.4    Kudo, Y.5    Liao, C.H.6
  • 58
    • 38049049272 scopus 로고    scopus 로고
    • Differential bonding interactions of inverse agonists of angiotensin II type 1 receptor in stabilizing the inactive state
    • Miura S, Kiya Y, Kanazawa T, Imaizumi S, Fujino M, Matsuo Y, et al. Differential bonding interactions of inverse agonists of angiotensin II type 1 receptor in stabilizing the inactive state. Mol Endocrinol 2008; 22: 139-146.
    • (2008) Mol Endocrinol , vol.22 , pp. 139-146
    • Miura, S.1    Kiya, Y.2    Kanazawa, T.3    Imaizumi, S.4    Fujino, M.5    Matsuo, Y.6
  • 59
    • 84862777926 scopus 로고    scopus 로고
    • Olmesartan attenuates the development of heart failure after experimental autoimmune myocarditis in rats through the modulation of ANG 1-7 mas receptor
    • Sukumaran V, Veeraveedu PT, Gurusamy N, Lakshmanan AP, Yamaguchi K, Ma M, et al. Olmesartan attenuates the development of heart failure after experimental autoimmune myocarditis in rats through the modulation of ANG 1-7 mas receptor. Mol Cell Endocrinol 2012; 351: 208-219.
    • (2012) Mol Cell Endocrinol , vol.351 , pp. 208-219
    • Sukumaran, V.1    Veeraveedu, P.T.2    Gurusamy, N.3    Lakshmanan, A.P.4    Yamaguchi, K.5    Ma, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.