메뉴 건너뛰기




Volumn 55, Issue 1, 2014, Pages 17-29

Historical perspectives on the impact of n-3 and n-6 nutrients on health

Author keywords

Alpha linolenic acid (18:3n 3); Eicosanoids; Essential fatty acids (EFA); Highly unsaturated fatty acids (HUFA); Linoleic acid (18:2n 6); Omega 6 (n 6); Polyunsaturated fatty acids (PUFA); Recommended dietary allowance (RDA); Therapeutic window; Tolerable upper intake level (UL)

Indexed keywords

OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PROSTAGLANDIN; UNSATURATED FATTY ACID;

EID: 84901253486     PISSN: 01637827     EISSN: 18732194     Source Type: Journal    
DOI: 10.1016/j.plipres.2014.04.002     Document Type: Review
Times cited : (110)

References (85)
  • 2
    • 84891614247 scopus 로고    scopus 로고
    • Twenty tips for interpreting scientific claims
    • W.J. Sutherland, D. Spiegelhalter, and M.A. Burgman Twenty tips for interpreting scientific claims Nature 503 2013 335 337
    • (2013) Nature , vol.503 , pp. 335-337
    • Sutherland, W.J.1    Spiegelhalter, D.2    Burgman, M.A.3
  • 3
    • 84956465034 scopus 로고
    • Essential fatty acids and human nutrition
    • A.E. Hansen, and G.O. Burr Essential fatty acids and human nutrition JAMA 132 1946 855 859
    • (1946) JAMA , vol.132 , pp. 855-859
    • Hansen, A.E.1    Burr, G.O.2
  • 4
    • 0000888229 scopus 로고
    • A new deficiency disease produced by the rigid exclusion of fat from the diet
    • G.O. Burr, and M.M. Burr A new deficiency disease produced by the rigid exclusion of fat from the diet J Biol Chem 82 1929 345 367
    • (1929) J Biol Chem , vol.82 , pp. 345-367
    • Burr, G.O.1    Burr, M.M.2
  • 5
    • 70449246507 scopus 로고
    • Essential fatty acids in infant nutrition. III. Clinical manifestations of linoleic acid deficiency
    • A.E. Hansen, M.E. Haggard, A.N. Boelsche, D.J.D. Adam, and H.F. Wiese Essential fatty acids in infant nutrition. III. Clinical manifestations of linoleic acid deficiency J Nutr 66 1958 565 576
    • (1958) J Nutr , vol.66 , pp. 565-576
    • Hansen, A.E.1    Haggard, M.E.2    Boelsche, A.N.3    Adam, D.J.D.4    Wiese, H.F.5
  • 6
    • 0000887245 scopus 로고
    • Role of linoleic acid in infant nutrition. Clinical and chemical study of 428 infants fed on milk mixtures varying in kind and amount of fat
    • A.E. Hansen, H.F. Wiese, A.N. Boelsche, M.E. Haggard, D.J.D. Adam, and H. Davis Role of linoleic acid in infant nutrition. Clinical and chemical study of 428 infants fed on milk mixtures varying in kind and amount of fat Pediatrics 31 1963 171 192
    • (1963) Pediatrics , vol.31 , pp. 171-192
    • Hansen, A.E.1    Wiese, H.F.2    Boelsche, A.N.3    Haggard, M.E.4    Adam, D.J.D.5    Davis, H.6
  • 7
    • 72949141958 scopus 로고
    • The ratio of trienoic: Tetraenoic acids in tissue lipids as a measure of essential fatty acid requirement
    • R.T. Holman The ratio of trienoic: tetraenoic acids in tissue lipids as a measure of essential fatty acid requirement J Nutr 70 1960 405 410
    • (1960) J Nutr , vol.70 , pp. 405-410
    • Holman, R.T.1
  • 8
    • 0343616660 scopus 로고
    • The essential fatty acid requirement of infants and the assessment of their dietary intake of linoleate by serum fatty acid analysis
    • R.T. Holman, W.O. Caster, and H.F. Wiese The essential fatty acid requirement of infants and the assessment of their dietary intake of linoleate by serum fatty acid analysis Am J Clin Nutr 14 1964 70 75
    • (1964) Am J Clin Nutr , vol.14 , pp. 70-75
    • Holman, R.T.1    Caster, W.O.2    Wiese, H.F.3
  • 9
    • 78651165832 scopus 로고
    • The effect of dose level of essential fatty acids upon fatty acid composition of the rat liver
    • H. Mohrhauer, and R.T. Holman The effect of dose level of essential fatty acids upon fatty acid composition of the rat liver J Lipid Res 4 1963 151 159
    • (1963) J Lipid Res , vol.4 , pp. 151-159
    • Mohrhauer, H.1    Holman, R.T.2
  • 10
    • 39749183516 scopus 로고    scopus 로고
    • A critique of paradoxes in current advice on dietary lipids
    • B. Lands A critique of paradoxes in current advice on dietary lipids Prog Lipid Res 47 2 2008 77 106
    • (2008) Prog Lipid Res , vol.47 , Issue.2 , pp. 77-106
    • Lands, B.1
  • 11
    • 37249002275 scopus 로고    scopus 로고
    • Whole body distribution of deuterated linoleic and α-linolenic acids and their metabolites in the rat
    • DOI 10.1194/jlr.M700369-JLR200
    • Y.H. Lin, and N. Salem Jr. Whole body distribution of deuterated linoleic and alpha-linolenic acids and their metabolites in the rat J Lipid Res 48 12 2007 2709 2724 (Pubitemid 350272856)
    • (2007) Journal of Lipid Research , vol.48 , Issue.12 , pp. 2709-2724
    • Yu, H.L.1    Salem Jr., N.2
  • 12
    • 0002885273 scopus 로고
    • Effect of linolenic acid upon the metabolism of linoleic acid
    • H. Mohrhauer, and R.T. Holman Effect of linolenic acid upon the metabolism of linoleic acid J Nutr 81 1963 67 74
    • (1963) J Nutr , vol.81 , pp. 67-74
    • Mohrhauer, H.1    Holman, R.T.2
  • 14
    • 0017081637 scopus 로고
    • Essential fatty acid requirements in infancy
    • W.F.J. Cuthbertson Essential fatty acid requirements in infancy Am J Clin Nutr 20 1976 559 568
    • (1976) Am J Clin Nutr , vol.20 , pp. 559-568
    • Cuthbertson, W.F.J.1
  • 15
    • 0003200564 scopus 로고
    • The Enzymatic conversion of essential fatty acids into prostaglandins
    • PC4006-8. PubMed PMID: 14257636
    • S. Bergstroem, H. Danielsson, D. Klenberg, and B. Samuelsson The Enzymatic conversion of essential fatty acids into prostaglandins J Biol Chem 239 1964 PC4006-8. PubMed PMID: 14257636
    • (1964) J Biol Chem , vol.239
    • Bergstroem, S.1    Danielsson, H.2    Klenberg, D.3    Samuelsson, B.4
  • 16
    • 0002075836 scopus 로고
    • Essential fatty acids
    • H.J. Thomasson Essential fatty acids Nature (Lond) 194 1962 973
    • (1962) Nature (Lond) , vol.194 , pp. 973
    • Thomasson, H.J.1
  • 17
    • 79959906412 scopus 로고    scopus 로고
    • Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: A proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope
    • Y. Zheng, H. Yin, W.E. Boeglin, P.M. Elias, D. Crumrine, and D.R. Beier et al. Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope J Biol Chem 286 27 2011 24046 24056
    • (2011) J Biol Chem , vol.286 , Issue.27 , pp. 24046-24056
    • Zheng, Y.1    Yin, H.2    Boeglin, W.E.3    Elias, P.M.4    Crumrine, D.5    Beier, D.R.6
  • 18
    • 84896739077 scopus 로고    scopus 로고
    • The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier
    • A. Muñoz-Garcia, C.P. Thomas, D.S. Keeney, Y. Zheng, and A.R. Brash The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier Biochim Biophys Acta 1841 2014 401 408
    • (2014) Biochim Biophys Acta , vol.1841 , pp. 401-408
    • Muñoz-Garcia, A.1    Thomas, C.P.2    Keeney, D.S.3    Zheng, Y.4    Brash, A.R.5
  • 19
    • 0018665496 scopus 로고
    • Inhibition of prostaglandin biosynthesis by eicosapentaenoic acid
    • DOI 10.1016/0161-4630(79)90068-5
    • B.R. Culp, B.G. Titus, and W.B.M. Lands Inhibition of prostaglandin biosynthesis by eicosapentaenoic acid Prostaglandins Med 3 1979 269 278 (Pubitemid 10218349)
    • (1979) Prostaglandins and Medicine , vol.3 , Issue.5 , pp. 269-278
    • Culp, B.R.1    Titus, B.G.2    Lands, W.E.M.3
  • 20
    • 0018726420 scopus 로고
    • The protective effects of dietary fish oil on focal cerebral infarction
    • DOI 10.1016/0161-4630(79)90067-3
    • K.L. Black, B.R. Culp, D. Madison, O.S. Randall, and W.E.M. Lands The protective effects of dietary fish oil on focal cerebral infarction Prostaglandins Med 3 1979 257 268 (Pubitemid 10218348)
    • (1979) Prostaglandins and Medicine , vol.3 , Issue.5 , pp. 257-268
    • Black, K.L.1    Culp, B.2    Madison, D.3
  • 21
    • 0019159289 scopus 로고
    • The effect of dietary supplementation of fish oil on experimental myocardial infarction
    • DOI 10.1016/0090-6980(80)90056-8
    • B.R. Culp, W.E.M. Lands, B.R. Lucchesi, B. Pitt, and J. Romson The effect of dietary supplementation of fish oil on experimental myocardial infarction Prostaglandins 20 1980 1021 1031 (Pubitemid 11189719)
    • (1980) Prostaglandins , vol.20 , Issue.6 , pp. 1021-1031
    • Culp, B.R.1    Lands, W.E.M.2    Lucchesi, B.R.3
  • 23
    • 0026060737 scopus 로고
    • Essential fatty acid deficiency impairs macrophage spreading and adherence: Role of arachidonate in cell adhesion
    • J.B. Lefkowith, M. Rogers, M.R. Lennartz, and E.J. Brown Essential fatty acid deficiency impairs macrophage spreading and adherence. Role of arachidonate in cell adhesion J Biol Chem 266 2 1991 1071 1076 PubMed PMID: 1985935 (Pubitemid 21907227)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.2 , pp. 1071-1076
    • Lefkowith, J.B.1    Rogers, M.2    Lennartz, M.R.3    Brown, E.J.4
  • 25
    • 0025132485 scopus 로고
    • Quantitative effects of dietary polyunsaturated fats on the composition of fatty acids in rat tissues
    • W.E.M. Lands, A.J. Morris, and B. Libelt Quantitative effects of dietary polyunsaturated fats on the composition of fatty acids in rat tissues Lipids 25 1990 505 516 (Pubitemid 20327610)
    • (1990) Lipids , vol.25 , Issue.9 , pp. 505-516
    • Lands, W.E.M.1    Morris, A.2    Libelt, B.3
  • 26
    • 0026447173 scopus 로고
    • Maintenance of lower proportions of n-6 eicosanoid precursors in phospholipids of human plasma in response to added dietary n-3 fatty acids
    • W.E.M. Lands, B. Libelt, A. Morris, N.C. Kramer, T.E. Prewitt, and P. Bowen et al. Maintenance of lower proportions of n-6 eicosanoid precursors in phospholipids of human plasma in response to added dietary n-3 fatty acids Biochem Biophys Acta 1180 1992 147 162
    • (1992) Biochem Biophys Acta , vol.1180 , pp. 147-162
    • Lands, W.E.M.1    Libelt, B.2    Morris, A.3    Kramer, N.C.4    Prewitt, T.E.5    Bowen, P.6
  • 28
    • 84901282817 scopus 로고    scopus 로고
    • Validation of an equation predicting highly unsaturated fatty acid compositions of human blood fractions from dietary intake
    • [Submitted]
    • Strandjord SE, Lands B, Hibbeln JR. Validation of an equation predicting highly unsaturated fatty acid compositions of human blood fractions from dietary intake. Nutr Metab [Submitted].
    • Nutr Metab
    • Strandjord, S.E.1    Lands, B.2    Hibbeln, J.R.3
  • 29
    • 30744440653 scopus 로고
    • Role of dietary fat in human nutrition. III. Diet and the epidemiology of coronary heart disease
    • A. Keys, and F. Grande Role of dietary fat in human nutrition. III. Diet and the epidemiology of coronary heart disease Am J Public Health Nations Health 47 12 1957 1520 1530
    • (1957) Am J Public Health Nations Health , vol.47 , Issue.12 , pp. 1520-1530
    • Keys, A.1    Grande, F.2
  • 32
    • 84965183779 scopus 로고
    • Levine VE Fat metabolism in Alaskan Eskimos
    • C.G. Wilber Levine VE Fat metabolism in Alaskan Eskimos Exp Med Surg 8 1950 422 425
    • (1950) Exp Med Surg , vol.8 , pp. 422-425
    • Wilber, C.G.1
  • 33
    • 0016809013 scopus 로고
    • Fatty acid composition of the plasma lipids in Greenland Eskimos
    • J. Dyerberg, H.O. Bang, and N. Hjorne Fatty acid composition of the plasma lipids in Greenland Eskimos Am J Clin Nutr 28 1975 958
    • (1975) Am J Clin Nutr , vol.28 , pp. 958
    • Dyerberg, J.1    Bang, H.O.2    Hjorne, N.3
  • 34
    • 0022982012 scopus 로고
    • The diet and 15-year death rate in the seven countries study
    • A. Keys, A. Menotti, M.J. Karvonen, C. Aravanis, H. Blackburn, and R. Buzina et al. The diet and 15-year death rate in the seven countries study Am J Epidemiol 124 6 1986 903 915 (Pubitemid 17207259)
    • (1986) American Journal of Epidemiology , vol.124 , Issue.6 , pp. 903-915
    • Keys, A.1    Menotti, A.2    Karvonen, M.J.3
  • 35
    • 0029060065 scopus 로고
    • Serum total cholesterol and long-term coronary heart disease mortality in different cultures. Twenty-five year follow-up of the seven countries study
    • W.M. Verschuren, D.R. Jacobs, B.P. Bloemberg, D. Kromhout, A. Menotti, and C. Aravanis et al. Serum total cholesterol and long-term coronary heart disease mortality in different cultures. Twenty-five year follow-up of the seven countries study JAMA 274 2 1995 131 136
    • (1995) JAMA , vol.274 , Issue.2 , pp. 131-136
    • Verschuren, W.M.1    Jacobs, D.R.2    Bloemberg, B.P.3    Kromhout, D.4    Menotti, A.5    Aravanis, C.6
  • 36
    • 0029016308 scopus 로고
    • The seven countries study in Japan. Twenty-five-year experience in cardiovascular and all-causes deaths
    • H. Toshima, Y. Koga, A. Menotti, A. Keys, H. Blackburn, and D.R. Jacobs et al. The seven countries study in Japan. Twenty-five-year experience in cardiovascular and all-causes deaths Jpn Heart J 36 2 1995 179 189
    • (1995) Jpn Heart J , vol.36 , Issue.2 , pp. 179-189
    • Toshima, H.1    Koga, Y.2    Menotti, A.3    Keys, A.4    Blackburn, H.5    Jacobs, D.R.6
  • 37
    • 77956023713 scopus 로고    scopus 로고
    • Blood choloesterol as a good marker of health in Japan
    • Y. Ogushi, T. Hamazaki, and Y. Kirihara Blood choloesterol as a good marker of health in Japan World Rev Nutr Diet 100 2009 63 70
    • (2009) World Rev Nutr Diet , vol.100 , pp. 63-70
    • Ogushi, Y.1    Hamazaki, T.2    Kirihara, Y.3
  • 38
    • 0037971513 scopus 로고    scopus 로고
    • Diets could prevent many diseases
    • DOI 10.1007/s11745-003-1066-0
    • W.E.M. Lands Diets could prevent many diseases Lipids 38 4 2003 317 321 (Pubitemid 36724288)
    • (2003) Lipids , vol.38 , Issue.4 , pp. 317-321
    • Lands, W.E.M.1
  • 39
    • 30444442520 scopus 로고    scopus 로고
    • Comparison of prostate cancer mortality in five countries: France, Italy, Japan, UK and USA from the WHO mortality database (1960-2000)
    • DOI 10.1093/jjco/hyi185
    • T. Marugame, and S. Mizuno Comparison of prostate cancer mortality in five countries: France, Italy, Japan, UK and USA from the WHO Mortality Database (1960-2000) Jpn J Clin Oncol 35 11 2005 690 691 (Pubitemid 43071449)
    • (2005) Japanese Journal of Clinical Oncology , vol.35 , Issue.11 , pp. 690-691
    • Marugame, T.1    Mizuno, S.2
  • 40
    • 67649094344 scopus 로고    scopus 로고
    • Planning primary prevention of coronary disease
    • B. Lands Planning primary prevention of coronary disease Curr Atheroscler Rep 11 4 2009 272 280
    • (2009) Curr Atheroscler Rep , vol.11 , Issue.4 , pp. 272-280
    • Lands, B.1
  • 42
    • 77956042095 scopus 로고    scopus 로고
    • Measuring blood fatty acids as a surrogate indicator for coronary heart disease risk in population studies
    • B. Lands Measuring blood fatty acids as a surrogate indicator for coronary heart disease risk in population studies World Rev Nutr Diet 100 2009 22 34
    • (2009) World Rev Nutr Diet , vol.100 , pp. 22-34
    • Lands, B.1
  • 43
    • 39149105639 scopus 로고    scopus 로고
    • The percentage of n-3 highly unsaturated fatty acids in total HUFA as a biomarker for omega-3 fatty acid status in tissues
    • K.D. Stark The percentage of n-3 highly unsaturated fatty acids in total HUFA as a biomarker for omega-3 fatty acid status in tissues Lipids 43 2008 45 53
    • (2008) Lipids , vol.43 , pp. 45-53
    • Stark, K.D.1
  • 46
    • 0025910140 scopus 로고
    • Biosynthesis of prostaglandins
    • W.E.M. Lands Biosynthesis of prostaglandins Annu Rev Nutr 11 1991 41 60 (Pubitemid 21903821)
    • (1991) Annual Review of Nutrition , vol.11 , Issue.1 , pp. 41-60
    • Lands, W.E.M.1
  • 49
    • 84861335943 scopus 로고    scopus 로고
    • Describing essential fatty acid balance as 3-6 differences rather than 3/6 ratios
    • B. Lands, and E. Lamoreaux Describing essential fatty acid balance as 3-6 differences rather than 3/6 ratios Nutr Metab 9 2012 46 54
    • (2012) Nutr Metab , vol.9 , pp. 46-54
    • Lands, B.1    Lamoreaux, E.2
  • 52
    • 0026760231 scopus 로고
    • Dietary lipids and coronary heart disease: Old evidence, new perspective
    • M.I. Gurr Dietary lipids and coronary heart disease: old evidence, new perspective Prog Lipid Res 31 3 1992 195 243
    • (1992) Prog Lipid Res , vol.31 , Issue.3 , pp. 195-243
    • Gurr, M.I.1
  • 53
    • 0027691227 scopus 로고
    • The role of fluid mechanics in the localization and detection of atherosclerosis
    • D.P. Giddens, C.K. Zarins, and S. Glagov The role of fluid mechanics in the localization and detection of atherosclerosis J Biomech Eng 115 4B 1993 588 594 (Pubitemid 24000887)
    • (1993) Journal of Biomechanical Engineering , vol.115 , Issue.4 , pp. 588-594
    • Giddens, D.P.1    Zarins, C.K.2    Glagov, S.3
  • 54
    • 0023949568 scopus 로고
    • 5 in complement receptor enhancement, lysozyme release and chemotaxis of human neutrophils
    • T.H. Lee, T. Sethi, A.E. Crea, W. Peters, J.P. Arm, and C.E. Horton et al. Characterization of leukotriene B3: comparison of its biological activities with leukotriene B4 and leukotriene B5 in complement receptor enhancement, lysozyme release and chemotaxis of human neutrophils Clin Sci (Lond) 74 5 1988 467 475 PubMed PMID: 2836122 (Pubitemid 18091884)
    • (1988) Clinical Science , vol.74 , Issue.5 , pp. 467-475
    • Lee, T.H.1    Sethi, T.2    Crea, A.E.G.3    Peters, W.4    Arm, J.P.5    Horton, C.E.6    Walport, M.J.7    Spur, B.W.8
  • 55
    • 0031049146 scopus 로고    scopus 로고
    • Effect of a single high-fat meal on endothelial function in healthy subjects
    • DOI 10.1016/S0002-9149(96)00760-6, PII S0002914996007606
    • R.A. Vogel, M.C. Corretti, and G.D. Plotnick Effect of a single high-fat meal on endothelial function in healthy subjects Am J Cardiol 79 3 1997 350 354 PubMed PMID: 9036757 (Pubitemid 27093313)
    • (1997) American Journal of Cardiology , vol.79 , Issue.3 , pp. 350-354
    • Vogel, R.A.1    Corretti, M.C.2    Plotnick, G.D.3
  • 58
    • 45849131719 scopus 로고    scopus 로고
    • Supplements of l-arginine attenuate the effects of high-fat meal on endothelial function and oxidative stress
    • DOI 10.1016/j.ijcard.2007.06.013, PII S0167527307010583
    • C.-C. Lin, W.-C. Tsai, J.-Y. Chen, Y.-H. Li, Y.-J. Lin, and J.-H. Chen Supplements of l-arginine attenuate the effects of high-fat meal on endothelial function and oxidative stress Int J Cardiol 127 2008 337 341 (Pubitemid 351885081)
    • (2008) International Journal of Cardiology , vol.127 , Issue.3 , pp. 337-341
    • Lin, C.-C.1    Tsai, W.-C.2    Chen, J.-Y.3    Li, Y.-H.4    Lin, L.-J.5    Chen, J.-H.6
  • 59
    • 84867405480 scopus 로고    scopus 로고
    • Postprandial lipaemia suppresses endothelium-dependent arterial dilation in patients with hypothyroidism
    • Epub 2012 Feb 22. PubMed PMID: 22354717
    • G.D. Xiang, L.W. Xiang, H.L. He, and L.S. Zhao Postprandial lipaemia suppresses endothelium-dependent arterial dilation in patients with hypothyroidism Endocrine 42 2 2012 391 398 Epub 2012 Feb 22. PubMed PMID: 22354717
    • (2012) Endocrine , vol.42 , Issue.2 , pp. 391-398
    • Xiang, G.D.1    Xiang, L.W.2    He, H.L.3    Zhao, L.S.4
  • 61
    • 84865066901 scopus 로고    scopus 로고
    • Effects of fatty acids on endothelial cells: Inflammation and monocyte adhesion
    • doi:10.1016/j.jss.2012.04.010 Epub 2012 Apr 27. PubMed PMID: 22572621
    • S.M. Grenon, J. Aguado-Zuniga, J.P. Hatton, C.D. Owens, M.S. Conte, and M. Hughes-Fulford Effects of fatty acids on endothelial cells: inflammation and monocyte adhesion J Surg Res 177 1 2012 e35 e43 http://dx.doi.org/10.1016/j.jss. 2012.04.010. Epub 2012 Apr 27. PubMed PMID: 22572621
    • (2012) J Surg Res , vol.177 , Issue.1
    • Grenon, S.M.1    Aguado-Zuniga, J.2    Hatton, J.P.3    Owens, C.D.4    Conte, M.S.5    Hughes-Fulford, M.6
  • 62
    • 84880668199 scopus 로고    scopus 로고
    • The energy content of restaurant foods without stated calorie information
    • doi:10.1001/jamainternmed.2013.6163 [Epub ahead of print] PubMed PMID: 23700076
    • L.E. Urban, A.H. Lichtenstein, C.E. Gary, J.L. Fierstein, A. Equi, and C. Kussmaul et al. The energy content of restaurant foods without stated calorie information JAMA Intern Med 2013 1 8 http://dx.doi.org/10.1001/jamainternmed. 2013.6163. [Epub ahead of print] PubMed PMID: 23700076
    • (2013) JAMA Intern Med , pp. 1-8
    • Urban, L.E.1    Lichtenstein, A.H.2    Gary, C.E.3    Fierstein, J.L.4    Equi, A.5    Kussmaul, C.6
  • 63
    • 84901281063 scopus 로고    scopus 로고
    • National Heart, Lung, and Blood Institute NHLBI Bethesda, MD
    • National Heart, Lung, and Blood Institute Fact book, fiscal year 2012 2013 NHLBI Bethesda, MD
    • (2013) Fact Book, Fiscal Year 2012
  • 64
    • 84880323061 scopus 로고    scopus 로고
    • Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes
    • The Look AHEAD Research Group 10.1056/NEJM oa1212914
    • The Look AHEAD Research Group Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes N Engl J Med 2013 10.1056/NEJM oa1212914
    • (2013) N Engl J Med
  • 65
  • 68
    • 49249097522 scopus 로고    scopus 로고
    • Heart disease: Not about cholesterol?
    • Carey J. Heart disease: not about cholesterol? Business Week 2008. .
    • (2008) Business Week
    • Carey, J.1
  • 69
    • 53749106592 scopus 로고    scopus 로고
    • Cholesterol veers off script
    • J. Couzin Cholesterol veers off script Science 322 2008 220 223
    • (2008) Science , vol.322 , pp. 220-223
    • Couzin, J.1
  • 70
    • 56749106312 scopus 로고    scopus 로고
    • Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
    • JUPITER Study Group
    • P.M. Ridker, E. Danielson, F.A. Fonseca JUPITER Study Group Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein N Engl J Med 359 2008 2195 2207
    • (2008) N Engl J Med , vol.359 , pp. 2195-2207
    • Ridker, P.M.1    Danielson, E.2    Fonseca, F.A.3
  • 71
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - An inflammatory disease
    • DOI 10.1056/NEJM199901143400207
    • R. Ross Atherosclerosis - an inflammatory disease N Engl J Med 340 1999 115 126 (Pubitemid 29054847)
    • (1999) New England Journal of Medicine , vol.340 , Issue.2 , pp. 115-126
    • Ross, R.1
  • 72
    • 0022423944 scopus 로고
    • Lowering blood cholesterol to prevent heart disease
    • Consensus conference
    • Consensus conference Lowering blood cholesterol to prevent heart disease JAMA 253 14 1985 2080 2086
    • (1985) JAMA , vol.253 , Issue.14 , pp. 2080-2086
  • 73
    • 84873688136 scopus 로고    scopus 로고
    • Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: Evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis
    • doi:10.1136/bmj.e8707 Erratum in: BMJ. 2013;346:f903. PubMed PMID: 23386268
    • C.E. Ramsden, D. Zamora, B. Leelarthaepin, S.F. Majchrzak-Hong, K.R. Faurot, and C.M. Suchindran et al. Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis BMJ 346 2013 e8707 http://dx.doi.org/10.1136/bmj.e8707. Erratum in: BMJ. 2013;346:f903. PubMed PMID: 23386268
    • (2013) BMJ , vol.346 , pp. 8707
    • Ramsden, C.E.1    Zamora, D.2    Leelarthaepin, B.3    Majchrzak-Hong, S.F.4    Faurot, K.R.5    Suchindran, C.M.6
  • 74
    • 84872091789 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2013 update
    • D. Mozaffarian, and L.R. Véronique et al. Heart disease and stroke statistics - 2013 update Circulation 127 2013 e6 e245
    • (2013) Circulation , vol.127
    • Mozaffarian, D.1    Véronique, L.R.2
  • 76
    • 84878788564 scopus 로고    scopus 로고
    • Incorporating macadamia oil and butter to reduce dietary omega-6 polyunsaturated fatty acid intake
    • K.E. Wood, E. Mantzioris, R.A. Gibson, and B.S. Muhlhausler Incorporating macadamia oil and butter to reduce dietary omega-6 polyunsaturated fatty acid intake Nutr Diet 70 2013 94 100
    • (2013) Nutr Diet , vol.70 , pp. 94-100
    • Wood, K.E.1    Mantzioris, E.2    Gibson, R.A.3    Muhlhausler, B.S.4
  • 77
    • 84886262321 scopus 로고    scopus 로고
    • Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: A randomized trial
    • doi:10.1016/j.pain.2013.07.028 Epub 2013 Jul 22. PubMed PMID: 23886520
    • C.E. Ramsden, K.R. Faurot, D. Zamora, C.M. Suchindran, B.A. Macintosh, and S. Gaylord et al. Targeted alteration of dietary n-3 and n-6 fatty acids for the treatment of chronic headaches: a randomized trial Pain 154 11 2013 2441 2451 http://dx.doi.org/10.1016/j.pain.2013.07.028. Epub 2013 Jul 22. PubMed PMID: 23886520
    • (2013) Pain , vol.154 , Issue.11 , pp. 2441-2451
    • Ramsden, C.E.1    Faurot, K.R.2    Zamora, D.3    Suchindran, C.M.4    Macintosh, B.A.5    Gaylord, S.6
  • 78
    • 84873695766 scopus 로고    scopus 로고
    • Low-n-6 and low-n-6 plus high-n-3 diets for use in clinical research
    • doi:10.1017/S0007114512005181 Epub 2013 Jan 18. PubMed PMID: 23328113
    • B.A. MacIntosh, C.E. Ramsden, K.R. Faurot, D. Zamora, M. Mangan, and J.R. Hibbeln et al. Low-n-6 and low-n-6 plus high-n-3 diets for use in clinical research Br J Nutr 110 3 2013 559 568 http://dx.doi.org/10.1017/ S0007114512005181. Epub 2013 Jan 18. PubMed PMID: 23328113
    • (2013) Br J Nutr , vol.110 , Issue.3 , pp. 559-568
    • Macintosh, B.A.1    Ramsden, C.E.2    Faurot, K.R.3    Zamora, D.4    Mangan, M.5    Hibbeln, J.R.6
  • 79
    • 85073390200 scopus 로고    scopus 로고
    • EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion related to the Tolerable Upper Intake Level of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA) [48pp]
    • EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion related to the Tolerable Upper Intake Level of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA). EFSA J 2012;10(7):2815. [48pp].
    • (2012) EFSA J , vol.10 , Issue.7 , pp. 2815
  • 81
    • 84873078805 scopus 로고    scopus 로고
    • Medical care savings from workplace wellness programs: What is a realistic savings potential?
    • PubMed PMID: 23263453
    • H. Bolnick, F. Millard, and J.P. Dugas Medical care savings from workplace wellness programs: what is a realistic savings potential? J Occup Environ Med 55 1 2013 4 9 PubMed PMID: 23263453
    • (2013) J Occup Environ Med , vol.55 , Issue.1 , pp. 4-9
    • Bolnick, H.1    Millard, F.2    Dugas, J.P.3
  • 82
    • 84888253863 scopus 로고    scopus 로고
    • Implausible results in human nutrition research
    • J.P. Ioannidis Implausible results in human nutrition research BMJ 14 2013 347 348
    • (2013) BMJ , vol.14 , pp. 347-348
    • Ioannidis, J.P.1
  • 84
    • 81155152449 scopus 로고    scopus 로고
    • Prevent the cause, not just the symptoms
    • B. Lands Prevent the cause, not just the symptoms Prostaglandins Other Lipid Mediat 96 2011 90 93
    • (2011) Prostaglandins Other Lipid Mediat , vol.96 , pp. 90-93
    • Lands, B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.