-
1
-
-
45449084795
-
Cellular senescence and organismal aging
-
Jeyapalan JC and Sedivy JM: Cellular senescence and organismal aging. Mech Ageing Dev 129: 467-474, 2008.
-
(2008)
Mech Ageing Dev
, vol.129
, pp. 467-474
-
-
Jeyapalan, J.C.1
Sedivy, J.M.2
-
2
-
-
0036829090
-
Cancer and aging: A model for the cancer promoting effects of the aging stroma
-
Krtolica A and Campisi J: Cancer and aging: a model for the cancer promoting effects of the aging stroma. Int J Biochem Cell Biol 34: 1401-1414, 2002.
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1401-1414
-
-
Krtolica, A.1
Campisi, J.2
-
3
-
-
13944249618
-
DNA repair, genome stability, and aging
-
Lombard DB, Chua KF, Mostoslavsky R, et al: DNA repair, genome stability, and aging. Cell 120: 497-512, 2005.
-
(2005)
Cell
, vol.120
, pp. 497-512
-
-
Lombard, D.B.1
Chua, K.F.2
Mostoslavsky, R.3
-
4
-
-
66849138420
-
Role of p53 in the anti-proliferative effects of Sirt1 inhibition in prostate cancer cells
-
Jung-Hynes B and Ahmad N: Role of p53 in the anti-proliferative effects of Sirt1 inhibition in prostate cancer cells. Cell Cycle 8: 1478-1483, 2009.
-
(2009)
Cell Cycle
, vol.8
, pp. 1478-1483
-
-
Jung-Hynes, B.1
Ahmad, N.2
-
5
-
-
77953292238
-
SIRT1 and p53, effect on cancer, senescence and beyond
-
Yi J and Luo J: SIRT1 and p53, effect on cancer, senescence and beyond. Biochim Biophys Acta 1804: 1684-1689, 2010.
-
(2010)
Biochim Biophys Acta
, vol.1804
, pp. 1684-1689
-
-
Yi, J.1
Luo, J.2
-
6
-
-
62449178216
-
The critical role of the class III histone deacetylase SIRT1 in cancer
-
Liu T, Liu PY and Marshall GM: The critical role of the class III histone deacetylase SIRT1 in cancer. Cancer Res 69: 1702-1705, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 1702-1705
-
-
Liu, T.1
Liu, P.Y.2
Marshall, G.M.3
-
7
-
-
79955469653
-
Sirtuin 1 in malignant transformation: Friend or foe?
-
Fang Y and Nicholl MB: Sirtuin 1 in malignant transformation: friend or foe? Cancer Lett 306: 10-14, 2011.
-
(2011)
Cancer Lett
, vol.306
, pp. 10-14
-
-
Fang, Y.1
Nicholl, M.B.2
-
8
-
-
67650445737
-
Distinct HIC1-SIRT1-p53 loop deregulation in lung squamous carcinoma and adenocarcinoma patients
-
Tseng RC, Lee CC, Hsu HS, et al: Distinct HIC1-SIRT1-p53 loop deregulation in lung squamous carcinoma and adenocarcinoma patients. Neoplasia 11: 763-770, 2009.
-
(2009)
Neoplasia
, vol.11
, pp. 763-770
-
-
Tseng, R.C.1
Lee, C.C.2
Hsu, H.S.3
-
9
-
-
62749133315
-
SIRT1, is it a tumor promoter or tumor suppressor?
-
Deng CX: SIRT1, is it a tumor promoter or tumor suppressor? Int J Biol Sci 5: 147-152, 2009.
-
(2009)
Int J Biol Sci
, vol.5
, pp. 147-152
-
-
Deng, C.X.1
-
10
-
-
38749088678
-
DBC1 is a negative regulator of SIRT1
-
Kim JE, Chen J and Lou Z: DBC1 is a negative regulator of SIRT1. Nature 451: 583-586, 2008.
-
(2008)
Nature
, vol.451
, pp. 583-586
-
-
Kim, J.E.1
Chen, J.2
Lou, Z.3
-
11
-
-
33847035824
-
Phosphorylation of HuR by Chk2 regulates SIRT1 expression
-
Abdelmohsen K, Pullmann R Jr, Lal A, et al: Phosphorylation of HuR by Chk2 regulates SIRT1 expression. Mol Cell 25: 543-557, 2007.
-
(2007)
Mol Cell
, vol.25
, pp. 543-557
-
-
Abdelmohsen, K.1
Pullmann Jr., R.2
Lal, A.3
-
12
-
-
35349011726
-
Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity
-
Kim EJ, Kho JH, Kang MR and Um SJ: Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity. Mol Cell 28: 277-290, 2007.
-
(2007)
Mol Cell
, vol.28
, pp. 277-290
-
-
Kim, E.J.1
Kho, J.H.2
Kang, M.R.3
Um, S.J.4
-
13
-
-
28544444366
-
Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival
-
Ford J, Jiang M and Milner J: Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival. Cancer Res 65, 10457-10463, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 10457-10463
-
-
Ford, J.1
Jiang, M.2
Milner, J.3
-
14
-
-
34547100073
-
SIRT1 is significantly elevated in mouse and human prostate cancer
-
Huffman DM, Grizzle WE, Bamman MM, et al: SIRT1 is significantly elevated in mouse and human prostate cancer. Cancer Res 67: 6612-6618, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 6612-6618
-
-
Huffman, D.M.1
Grizzle, W.E.2
Bamman, M.M.3
-
15
-
-
27144475816
-
Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors
-
Bradbury C, Khanim FL, Hayden R, et al: Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors. Leukemia 19: 1751-1759, 2005.
-
(2005)
Leukemia
, vol.19
, pp. 1751-1759
-
-
Bradbury, C.1
Khanim, F.L.2
Hayden, R.3
-
16
-
-
67650563916
-
SirT1 is an inhibitor of proliferation and tumor formation in colon cancer
-
Kabra N, Li Z, Chen L, et al: SirT1 is an inhibitor of proliferation and tumor formation in colon cancer. J Biol Chem 284: 18210-18217, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 18210-18217
-
-
Kabra, N.1
Li, Z.2
Chen, L.3
-
17
-
-
3242719545
-
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
-
Yeung F, Hoberg JE, Ramsey CS, et al: Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 23: 2369-2380, 2004
-
(2004)
EMBO J
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
-
18
-
-
43049163953
-
Acetylation is indispensable for p53 activation
-
Tang, Y, Zhao W, Chen Y, Zhao Y and Gu W: Acetylation is indispensable for p53 activation. Cell 133: 612-626, 2008.
-
(2008)
Cell
, vol.133
, pp. 612-626
-
-
Tang, Y.1
Zhao, W.2
Chen, Y.3
Zhao, Y.4
Gu, W.5
-
19
-
-
33748200050
-
Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage
-
Wang C, Chen L, Hou X, et al: Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage. Nat Cell Biol 8: 1025-1031, 2006.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1025-1031
-
-
Wang, C.1
Chen, L.2
Hou, X.3
-
20
-
-
36549044009
-
Function of the SIRT1 protein deacetylase in cancer
-
Stünkel W, Peh BK, Tan YC, et al: Function of the SIRT1 protein deacetylase in cancer. Biotechnol J 2: 1360-1368, 2007.
-
(2007)
Biotechnol J
, vol.2
, pp. 1360-1368
-
-
Stünkel, W.1
Peh, B.K.2
Tan, Y.C.3
-
21
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A, Sweeney LB, Sturgill JF, et al: Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303: 2011-2015, 2004.
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
-
22
-
-
24744469490
-
SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress
-
Kobayashi Y, Furukawa-Hibi Y, Chen C, et al: SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress. Int J Mol Med 16: 237-243, 2005.
-
(2005)
Int J Mol Med
, vol.16
, pp. 237-243
-
-
Kobayashi, Y.1
Furukawa-Hibi, Y.2
Chen, C.3
-
23
-
-
78049410740
-
Stimulation of Sirt1-regulated FoxO protein function by the ligand-bound vitamin D receptor
-
An BS, Tavera-Mendoza LE, Dimitrov V, et al: Stimulation of Sirt1-regulated FoxO protein function by the ligand-bound vitamin D receptor. Mol Cell Biol 30: 4890-4900, 2010.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 4890-4900
-
-
An, B.S.1
Tavera-Mendoza, L.E.2
Dimitrov, V.3
-
24
-
-
84871086291
-
Psf3 is a prognostic biomarker in lung adenocarcinoma
-
Hokka D, Maniwa Y, Tane S, et al: Psf3 is a prognostic biomarker in lung adenocarcinoma. Lung Cancer 79: 77-82, 2013.
-
(2013)
Lung Cancer
, vol.79
, pp. 77-82
-
-
Hokka, D.1
Maniwa, Y.2
Tane, S.3
-
25
-
-
79954664195
-
Oncogenic hosphatase Wip1 is a novel prognostic marker for lung adenocarcinoma patient survival
-
Satoh N, Maniwa Y, Bermudez VP, Nishimura K, Nishio W, Yoshimura M, et al: Oncogenic hosphatase Wip1 is a novel prognostic marker for lung adenocarcinoma patient survival. Cancer Sci 102: 1101-1106, 2011.
-
(2011)
Cancer Sci
, vol.102
, pp. 1101-1106
-
-
Satoh, N.1
Maniwa, Y.2
Bermudez, V.P.3
Nishimura, K.4
Nishio, W.5
Yoshimura, M.6
-
26
-
-
77953192863
-
Overexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma
-
Nakai R, Maniwa Y, Tanaka Y, Nishio W, Yoshimura M, Okita Y, et al: Overexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma. Cancer Sci 101: 1326-1330, 2010.
-
(2010)
Cancer Sci
, vol.101
, pp. 1326-1330
-
-
Nakai, R.1
Maniwa, Y.2
Tanaka, Y.3
Nishio, W.4
Yoshimura, M.5
Okita, Y.6
-
27
-
-
33751169387
-
Hypoxia-inducible factor-1 (HIF-1)
-
Ke Q and Costa M: Hypoxia-inducible factor-1 (HIF-1). Mol Pharmacol 70: 1469-1480, 2006
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1469-1480
-
-
Ke, Q.1
Costa, M.2
-
28
-
-
0342433777
-
Hypoxia-inducible factor (HIF-1) and its relationship to apoptosis and proliferation in lung cancer
-
Volm M and Koomägi R: Hypoxia-inducible factor (HIF-1) and its relationship to apoptosis and proliferation in lung cancer. Anticancer Res 20: 1527-1533, 2000.
-
(2000)
Anticancer Res
, vol.20
, pp. 1527-1533
-
-
Volm, M.1
Koomägi, R.2
-
29
-
-
4944246547
-
The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis
-
Greijer AE and van der Wall E: The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis. J Clin Pathol 57: 1009-1014, 2004.
-
(2004)
J Clin Pathol
, vol.57
, pp. 1009-1014
-
-
Greijer, A.E.1
van der Wall, E.2
-
30
-
-
33846331650
-
Oxidative stress and cancer: Have we moved forward?
-
Halliwell B: Oxidative stress and cancer: have we moved forward? Biochem J 401: 1-11, 2007.
-
(2007)
Biochem J
, vol.401
, pp. 1-11
-
-
Halliwell, B.1
-
31
-
-
58849158388
-
How does SIRT1 affect metabolism, senescence and cancer?
-
Brooks CL and Gu W: How does SIRT1 affect metabolism, senescence and cancer? Nat Rev Cancer 9: 123-128, 2009.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 123-128
-
-
Brooks, C.L.1
Gu, W.2
|