A derivative of oleamide potently inhibits the spontaneous metastasis of mouse melanoma BL6 cells

Carcinogenesis

Volumn 25, Issue 10, 2004, Pages 2015-2022

  Ito, Akihiko ^a   Morita, Nobuyoshi ^b   Miura, Daisaku ^d   Koma, Yu Ichiro ^a   Kataoka, Tatsuki R ^a   Yamasaki, Hiroshi ^e   Kitamura, Yukihiko ^a   Kita, Yasuyuki ^b   Nojima, Hiroshi ^c  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d Biosafety Research Center for Foods Drugs and Pesticides   (Japan)

^e KWANSEI GAKUIN UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMETASTATIC AGENT; CONNEXIN 26; CONNEXIN 43; GAP JUNCTION PROTEIN; MI 18; MI 89; OLEAMIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER SURVIVAL; CARCINOGENESIS; CELL COMMUNICATION; CONTROLLED STUDY; DRUG POTENCY; DRUG SAFETY; DRUG STRUCTURE; DRUG SYNTHESIS; GAP JUNCTION; HELA CELL; HUMAN; HUMAN CELL; LUNG METASTASIS; LYMPH NODE METASTASIS; MALE; MELANOMA; MELANOMA CELL; METASTASIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION; SURVIVAL RATE;

ANIMALS; CELL COMMUNICATION; CONNEXIN 43; CONNEXINS; GAP JUNCTIONS; HELA CELLS; HUMANS; INJECTIONS, INTRAPERITONEAL; LYMPHATIC METASTASIS; MELANOMA, EXPERIMENTAL; MICE; OLEIC ACIDS; SKIN NEOPLASMS; SURVIVAL RATE; TRANSFECTION;

EID: 6444221366     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh208     Document Type: Article

References (43)

1. Chin,L. (2003) The genetics of malignant melanoma: lessons from mouse and man. Nat. Rev. Cancer, 3, 559-570.
2. Hart,I.R. (1979) The selection and characterization of an invasive variant of the B16 melanoma. Am. J. Pathol., 97, 587-600.
3. Poste,G., Doll,J., Hart,I.R. and Fidler,I.J. (1980) In vivo selection of murine B16 melanoma variants with enhanced tissue-invasive properties. Cancer Res., 40, 1636-1644.
4. Maslow,D.E. (1989) Tabulation of results on the heterogeneity of cellular characteristics among cells from B16 mouse melanoma cell lines with different colonization potentials. Invas. Metast., 9 182-191.
5. Ito,A., Kataoka,T.R., Watanabe,M., Nishiyama,K., Mazaki,Y., Sabe,H., Kitamura,Y. and Nojima H. (2000) A truncated isoform of the PP2A B56 subunit promotes cell motility through paxillin phosphorylation. EMBO J., 19, 562-571.
6. Nakamoto,K., Ito,A, Watabe,K., Koma,Y., Asada,H., Yoshikawa,K., Shinomura,Y., Matsuzawa,Y., Nojima,H. and Kitamura,Y. (2001) Increased expression of a nucleolar Nop5/Sik family member in metastatic melanoma cells: evidence for its role in nucleolar sizing and function. Am. J. Pathol., 159, 1363-1374.
7. Ito,A., Katoh,F., Kataoka,T.R. et al. (2000) A role for heterologous gap junctions between melanoma and endothelial cells in metastasis. J. Clin. Invest., 105, 1189-1197.
8. Duflot-Dancer,A., Mesnil,M. and Yamasaki,H. (1997) Dominant-negative abrogation of connexin-mediated cell growth control by mutant connexin genes. Oncogene, 15, 2151-2158.
9. Evans,W.H. and Martin,P.E.M. (2002) Gap junctions: structure and function. Mol. Membr. Biol., 19, 121-136.
10. Goodenough,D.A. and Paul,D.L. (2003) Beyond the gap: functions of impaired connexon channels. Nat. Rev. Mol. Cell Biol., 4, 285-294.
11. Gerido,D.A. and White,T.W. (2004) Connexin disorders of the ear, skin and lens. Biochim. Biophys. Acta, 1662, 159-170.
12. Krutovskikh,V. and Yamasaki,H. (2000) Connexin gene mutations in human genetic diseases. Mutat. Res., 462, 197-207.
13. Kelsell,D.P., Dunlop,J. and Hodgins,M.B. (2001) Human diseases: clues to cracking the connexin code? Trends Cell Biol., 11, 2-6.
14. Kenneson,A., Van Naarden Braun,K. and Boyle,C. (2002) GJB2 (connexin 26) variants and nonsyndromic sensorineural hearing loss: a HuGE. Genet. Med., 4, 258-274.
15. Yamasaki,H., Omori,Y., Krutovskikh,V., Zhu,W., Mironov,N., Yamakage,K. and Mesnil,M. (1999) Connexins in tumour suppression and cancer therapy. Novartis Found. Symp., 219, 241-254.
16. Vine,A.L. and Bertram,J.S. (2002) Cancer chemoprevention by connexins. Cancer Metastasis Rev., 21, 199-216.
17. Saito,T., Nishimura,M., Kudo,R. and Yamasaki,H. (2001) Suppressed gap junctional intercellular communication in carcinogenesis of endometrium. Int. J. Cancer, 93, 317-323.
18. Arishima,H., Sato,K. and Kubota,T. (2002) Immunohistochemical and ultrastructural study of gap junction proteins connexin26 and 43 in human arachnoid villi and meningeal tumors. J. Neuropathol. Exp. Neurol., 61, 1048-1055.
19. Loncarek,J., Yamasaki,H., Levillain,P., Milinkevitch,S. and Mesnil,M. (2003) The expression of the tumor suppressor gene connexin 26 is not mediated by methylation in human esophageal cancer cells. Mol. Carcinogen., 36, 74-81.
20. Gee,J., Tanaka,M. and Grossman,H.B. (2003) Connexin 26 is abnormally expressed in bladder cancer. J. Urol., 169, 1135-1137.
21. Plante,I., Charbonneau,M. and Cyr,D.G. (2002) Decreased gap junctional intercellular communication in hexachlorobenzene- induced gender-specific hepatic tumor formation in the rat. Carcinogenesis, 23, 1243-1249.
22. Yano,T., Hernandez-Blazquez,F.J., Omori,Y. and Yamasaki,H. (2001) Reduction of malignant phenotype of HEPG2 cell is associated with the expression of connexin 26 but not connexin 32. Carcinogenesis, 22, 1593-1600.
23. Tanaka,M. and Grossman,H.B. (2004) Connexin 26 induces growth suppression, apoptosis and increased efficacy of doxorubicin in prostate cancer cells. Oncol. Rep., 11, 537-541.
24. Nicolson,G.L., Dulski,K.M. and Trosko,J.E. (1988) Loss of intercellular junctional communication correlates with metastatic potential in mammary adenocarcinoma cells. Proc. Natl Acad. Sci. USA 85, 473-476.
25. Jamieson,S., Going,J.J., D'Arcy,R. and George,W.D. (1998) Expression of gap junction proteins connexin 26 and connexin 43 in normal human breast and in breast tumours. J. Pathol., 184, 37-43.
26. Guan,X., Cravatt,B.F., Ehring,G.R., Hall,J.E., Boger,D.L., Lerner,R.A. and Gilula,N.B. (1997) The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells. J. Cell Biol., 139, 1785-1792.
27. Boger,D.L., Patterson,J.E., Guan,X., Cravatt,B.F., Lerner,R.A. and Gilula,N.B. (1998) Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide. Proc. Natl Acad. Sci. USA, 95, 4810-4815.
28. Akagi,T., Shishido,T., Murata,K. and Hanafusa,H. (2000) v-Crk activates the phosphoinositide 3-kinase/AKT pathway in transformation. Proc. Natl Acad. Sci. USA, 97, 7290-7295.
29. Omori,Y. and Yamasaki,H. (1998) Mutated connexin43 proteins inhibit rat glioma cell growth suppression mediated by wild-type connexin43 in a dominant negative manner. Int. J. Cancer, 78, 446-453.
30. Gutstein,D.E., Morley,G.E., Tamaddon,H., Vaidya,D., Schneider,M.D., Chen,J., Chien,K.R., Stuhlmann,H. and Fishman,G.I. (2001) Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43. Circ. Res., 88 333-339.
31. Thelmo,M.C., Morita,E.T., Treseler,P.A., Nguyen,L.H., Allen,R.E.Jr, Sagebie],R.W., Kashani-Sabet,M. and Leong,S.P. (2001) Micrometastasis to in-transit lymph nodes from extremity and truncal malignant melanoma. Ann. Surg. Oncol., 8, 444-448.
32. Mesnil,M., Krutovskikh,V., Piccoli,C., Elfgang,C., Traub,O., Willecke,K. and Yamasaki,H. (1995) Negative growth control of HeLa cells by connexin genes: connexin species specificity. Cancer Res., 55 629-639.
33. Yamasaki,H. and Naus,C.C.G. (1996) Role of connexin genes in growth control. Carcinogenesis, 17, 1199-1213.
34. Hirschi,K.K., Xu,C., Tsukamoto,T. and Sager,R. (1996) Gap junction genes Cx26 and Cx43 individually suppress the cancer phenotype of human mammary carcinoma cells and restore differential potential. Cell Growth Difter., 7, 861-870.
35. Zhang,W., Couldwell,W.T., Simard,M.F., Song,H., Lin,J.H. and Nedergaard,M. (1999) Direct gap junction communication between malignant glioma cells and astrocytes. Cancer Res., 59, 1994-2003.
36. Lin,J.H., Takano,T., Cotrina,M.L. et al. (2002) Connexin 43 enhances the adhesivity and mediates the invasion of malignant glioma cells. J. Neurosci., 22, 4302-4311.
37. Simon,A.M. and McWhorter,A.R. (2002) Vascular abnormalities in mice lacking the endothelial gap junction proteins connexin37 and connexin40. Dev. Biol., 251, 206-220.
38. Trosko,J.E. (2003) The role of stem cells and gap junctional intercellular communication in carcinogenesis. J. Biochem. Mol. Biol. 36, 43-48.
39. Al-Hajj,M., Becker,M.W., Wicha,M., Weissman,I. and Clarke,M.F. (2004) Therapeutic implications of cancer stem cells. Curr. Opin. Genet. Dev., 14, 43-47.
40. Curran,S. and Murray,G.I. (1999) Matrix metalloproteinases in tumor invasion and metastasis. J. Pathol., 189, 300-308.
41. Stamenkovic,I. (2000) Matrix metalloproteinases in tumor invasion and metastasis. Semin. Cancer Biol., 10, 415-433.
42. Jiang,Y., Goldberg,I.D. and Shi,Y.E. (2002) Complex roles of tissue inhibitors of metalloproteinases in cancer. Oncogene, 21 2245-2252.
43. Egeblad,M. and Werb,Z. (2002) New functions for the matrix metallo-proteinases in cancer progression. Nature Rev., 2, 163-176.