SERPINB3 protects from oxidative damage by chemotherapeutics through inhibition of mitochondrial respiratory complex I

Oncotarget

Volumn 5, Issue 9, 2014, Pages 2418-2427

  Ciscato, Francesco ^a   Sciacovelli, Marco ^a,b   Villano, Gianmarco ^a   Turato, Cristian ^a   Bernardi, Paolo ^a   Rasola, Andrea ^a   Pontisso, Patrizia ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b HUTCHISON MRC RESEARCH CENTRE   (United Kingdom)

Author keywords

Cell death; Chemotherapeutics; Mitochondria; Reactive oxygen species; Respiratory complexes; SERPINB3

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; CITRATE SYNTHASE; DOXORUBICIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SERINE PROTEINASE INHIBITOR; CARRIER PROTEIN; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; SQUAMOUS CELL CARCINOMA-RELATED ANTIGEN; TUMOR ANTIGEN;

APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY ASSAY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVITY; ENZYME ASSAY; GENETIC TRANSFECTION; HEPATOMA CELL; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MITOCHONDRIAL PERMEABILITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN INTERACTION; PROTEIN LOCALIZATION; TRANSGENIC MOUSE; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CALCIUM SIGNALING; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; DRUG EFFECTS; DRUG RESISTANCE; LIVER NEOPLASMS; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; PATHOLOGY; TUMOR CELL CULTURE;

ANTIGENS, NEOPLASM; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CALCIUM SIGNALING; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; DRUG RESISTANCE, NEOPLASM; ELECTRON TRANSPORT COMPLEX I; HUMANS; IMMUNOPRECIPITATION; LIVER NEOPLASMS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; OXIDATION-REDUCTION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SERPINS; TUMOR CELLS, CULTURED;

EID: 84901236061     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1411     Document Type: Article

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