Squamous cell carcinoma antigen in human liver carcinogenesis

Journal of Clinical Pathology

Volumn 61, Issue 4, 2008, Pages 445-447

  Guido, M ^a   Roskams, T ^b   Pontisso, P ^a   Fassan, M ^a   Thung, S N ^c   Giacomelli, L ^a   Sergio, A ^d   Farinati, F ^a,d   Cillo, U ^a   Rugge, Massimo ^a,d,e  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

^e Istituto di Anatomia Patologica   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

SQUAMOUS CELL CARCINOMA ANTIGEN;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CARCINOGENESIS; LIVER CIRRHOSIS; MALE; PREVALENCE; PRIORITY JOURNAL; SCORING SYSTEM;

ADULT; AGED; ANTIGENS, NEOPLASM; CARCINOMA, HEPATOCELLULAR; CELL TRANSFORMATION, NEOPLASTIC; CROSS-SECTIONAL STUDIES; DIAGNOSIS, DIFFERENTIAL; HEPATOCYTES; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; MIDDLE AGED; PRECANCEROUS CONDITIONS; SERPINS; TUMOR MARKERS, BIOLOGICAL;

EID: 42049083137     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.2007.051383     Document Type: Article

References (22)

1. Bruix J, Boix L, Sala M, et al. BCLC Group Liver Unit. Focus on hepatocellular carcinoma. Cancer Cell 2004;5:215-9.
2. Llovet JM, Beaugrand M. Hepatocellular carcinoma: present status and future prospects. J Hepatol 2003;38:136-49.
3. Bosch FX, Ribes J, Borras J. Epidemiology of primary liver cancer. Sem Liv Dis 1999;19:271-85.
4. Suriawinata A, Ruliang Xu. An update on the molecular genetics of hepatocellular carcinoma. Sem Liv Dis 2004;24:77-88.
5. Borzio M, Fargion S, Borzio F, et al. Impact of large regenerative, low grade and high grade dysplastic nodules in hepatocellular carcinoma development. J Hepatol 2003;39:208-14.
6. Kato H. Expression and function of squamous cell carcinoma antigen. Anticancer Res 1996;16:2149-53.
7. Cataltepe S, Gornstein ER, Schick C, et al. Coexpression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissue and squamous cell carcinomas. J Histochem Cytochem 2000;48:113-22.
8. Pontisso P, Calabrese F, Benvegnu L, et al. Overexpression of squamous cell carcinoma antigen variants in hepatocellular carcinoma. Br J Cancer 2004;91:2103-7.
9. Giannelli G, Marinosci F, Sgarra C, et al. Clinical role of tissue and serum levels of SCCA antigen in hepatocellular carcinoma. Int J Cancer 2005;116:579-83.
10. Beneduce L, Castaldi F, Marino M, et al. Squamous cell carcinoma antigen-immunoglobulin M complexes as novel biomarkers for hepatocellular carcinoma. Cancer 2005;103:2558-65.
11. Giannelli G, Marinosci F, Trerotoli P, et al. SCCA antigen combined with alpha-fetoprotein as serologic markers of HCC. Int J Cancer 2005;117:506-9.
12. Giannelli G, Fransvea E, Trerotoli P, et al. Clinical validation of combined serological biomarkers for improved hepatocellular carcinoma diagnosis in 961 patients. Clin Chim Acta 2007;383:147- 52.
13. International Working Party. Terminology of nodular lesions of the liver. Hepatology 1995;22:983-93.
14. Ishak KG, Anthony PP, Sobin LH. Histological typing of tumors of the liver. Geneva: World Health Organization, 1994.
15. Roncalli M, Roz E, Coggi G, et al. The vascular profile of regenerative and dysplastic nodules of the cirrhotic liver: implications for diagnosis and classification. Hepatology 1999;30:1174-8.
16. Libbrecht L, Desmet V, Roskams T. Preneoplastic lesions in human hepatocarcinogenesis. Liver Int 2005;25:16-27.
17. Suminami Y, Nagashima S, Vujanovic NL, et al. Inhibition of apoptosis in human tumor cells by the tumor-associated serpin, SCC antigen-1. Br J Cancer 2000;82:981-9.
18. Suminami Y, Nagashima S, Murakami A, et al. Suppressor of squamous cell carcinoma (SCC) related serpina, SCC antigen, inhibits tumor growth wfth increased intratumor infiltration of natural killer cells. Cancer Res 2001;61:1776-80.
19. Morinaga S, Ishiwa N, Noguchi Y, et al. Growth index, assessed with Ki-67 and ssDNA labeling; a significant prognosticator for patients undergoing curative resection for hepatocellular carcinoma. J Surg Oncol 2005;92:331-6.
20. Koskinas J, Petraki K, Kavantzas N, et al. Hepatic expression of the proliferative marker Ki-67 and p53 protein in HBV or HCV cirrhosis in relation to dysplastic liver cell changes and hepatocellular carcinoma. J Viral Hepat 2005;12:635-41.
21. Sheen IS, Jeng KS, Wu JY. Is p53 gene mutation an indicator of the biological behaviors of recurrence of hepatocellular carcinoma? World J Gastroenterol 2003;9:1202-7.
22. Pontisso P, Quarta S, Caberlotto C, et al. Progressive increase of SCCA-IgM immune complexes in cirrhotic patients is associated with development of hepatocellular carcinoma. Int J Cancer 2006;119:735-40.