Histamine H4-receptors inhibit mast cell renin release in ischemia/reperfusion via protein kinase Cε-dependent aldehyde dehydrogenase type-2 activation

Journal of Pharmacology and Experimental Therapeutics

Volumn 349, Issue 3, 2014, Pages 508-517

  Aldi, Silvia ^a   Takano, Ken Ichi ^a   Tomita, Kengo ^a   Koda, Kenichiro ^a   Chan, Noel Y K ^a   Marino, Alice ^a   Salazar Rodriguez, Mariselis ^a   Thurmond, Robin L ^b   Levi, Roberto ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 2; HISTAMINE H4 RECEPTOR; PROTEIN KINASE C EPSILON; ALDEHYDE DEHYDROGENASE; ALDH2 PROTEIN, HUMAN; G PROTEIN COUPLED RECEPTOR; HISTAMINE RECEPTOR; HRH4 PROTEIN, MOUSE; RENIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; EX VIVO STUDY; GENE DELETION; HEART ARRHYTHMIA; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HUMAN; HUMAN CELL; ISCHEMIC PRECONDITIONING; MALE; MAST CELL; MAST CELL DEGRANULATION; MASTOCYTOMA CELL LINE; MOUSE; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; RECEPTOR UPREGULATION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RENIN RELEASE; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; ENZYMOLOGY; GENETICS; GUINEA PIG; IN VITRO STUDY; KNOCKOUT MOUSE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; REPERFUSION INJURY; SECRETION (PROCESS);

ALDEHYDE DEHYDROGENASE; ANIMALS; CELL DIFFERENTIATION; CELL LINE; ENZYME ACTIVATION; GUINEA PIGS; HUMANS; ISCHEMIC PRECONDITIONING; MAST CELLS; MICE; MICE, KNOCKOUT; MYOCARDIAL REPERFUSION INJURY; PROTEIN KINASE C-EPSILON; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; RENIN; RENIN-ANGIOTENSIN SYSTEM;

EID: 84901217967     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.114.214122     Document Type: Article

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