-
1
-
-
0033832073
-
Guanylyl cyclases and signaling by cyclic GMP
-
Lucas KA, Pitari GM, Kazerounian S, Ruiz-Stewart I, Park J, Schulz S, Chepenik KP, Waldman SA. Guanylyl cyclases and signaling by cyclic GMP. Pharmacol Rev. 2000;52:375-414.
-
(2000)
Pharmacol Rev
, vol.52
, pp. 375-414
-
-
Lucas, K.A.1
Pitari, G.M.2
Kazerounian, S.3
Ruiz-Stewart, I.4
Park, J.5
Schulz, S.6
Chepenik, K.P.7
Waldman, S.A.8
-
2
-
-
79955664087
-
Mammalian cyclic nucleotide phosphodiesterases: Molecular mechanisms and physiological functions
-
Francis SH, Blount MA, Corbin JD. Mammalian cyclic nucleotide phosphodiesterases: molecular mechanisms and physiological functions. Physiol Rev. 2011;91:651-690.
-
(2011)
Physiol Rev
, vol.91
, pp. 651-690
-
-
Francis, S.H.1
Blount, M.A.2
Corbin, J.D.3
-
3
-
-
0034033975
-
Rising behind NO: CGMPdependent protein kinases
-
Hofmann F, Ammendola A, Schlossmann J. Rising behind NO: cGMPdependent protein kinases. J Cell Sci. 2000;113:1671-1676.
-
(2000)
J Cell Sci
, vol.113
, pp. 1671-1676
-
-
Hofmann, F.1
Ammendola, A.2
Schlossmann, J.3
-
4
-
-
84855332748
-
Phosphodiesterases and subcellular compartmentalized cAMP signaling in the cardiovascular system
-
Stangherlin A, Zaccolo M. Phosphodiesterases and subcellular compartmentalized cAMP signaling in the cardiovascular system. Am J Physiol Heart Circ Physiol. 2012;302:H379-H390.
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.302
-
-
Stangherlin, A.1
Zaccolo, M.2
-
5
-
-
84861521214
-
Cyclic guanosine monophosphate signaling and phosphodiesterase-5 inhibitors in cardioprotection
-
1921-1927
-
Kukreja RC, Salloum FN, Das A. Cyclic guanosine monophosphate signaling and phosphodiesterase-5 inhibitors in cardioprotection. J Am Coll Cardiol. 2012;59:1921-1927.
-
(2012)
J Am Coll Cardiol
, pp. 59
-
-
Kukreja, R.C.1
Salloum, F.N.2
Das, A.3
-
6
-
-
84055182545
-
Cardiac uses of phosphodiesterase-5 inhibitors
-
Schwartz BG, Levine LA, Comstock G, Stecher VJ, Kloner RA. Cardiac uses of phosphodiesterase-5 inhibitors. J Am Coll Cardiol. 2012;59:9-15.
-
(2012)
J Am Coll Cardiol
, vol.59
, pp. 9-15
-
-
Schwartz, B.G.1
Levine, L.A.2
Comstock, G.3
Stecher, V.J.4
Kloner, R.A.5
-
7
-
-
0036350615
-
Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial K(ATP) channels in rabbits
-
Ockaili R, Salloum F, Hawkins J, Kukreja RC. Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial K(ATP) channels in rabbits. Am J Physiol Heart Circ Physiol. 2002;283: H1263-H1269.
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.283
-
-
Ockaili, R.1
Salloum, F.2
Hawkins, J.3
Kukreja, R.C.4
-
8
-
-
84856078223
-
Preconditioning by phosphodiesterase-5 inhibition improves therapeutic efficacy of adipose-derived stem cells following myocardial infarction in mice
-
Hoke NN, Salloum FN, Kass DA, Das A, Kukreja RC. Preconditioning by phosphodiesterase-5 inhibition improves therapeutic efficacy of adipose-derived stem cells following myocardial infarction in mice. Stem Cells. 2012;30:326-335.
-
(2012)
Stem Cells
, vol.30
, pp. 326-335
-
-
Hoke, N.N.1
Salloum, F.N.2
Kass, D.A.3
Das, A.4
Kukreja, R.C.5
-
9
-
-
33845977750
-
Cyclic GMP-dependent protein kinase Iα attenuates necrosis and apoptosis following ischemia/reoxygenation in adult cardiomyocyte
-
DOI 10.1074/jbc.M606142200
-
Das A, Smolenski A, Lohmann SM, Kukreja RC. Cyclic GMP-dependent protein kinase Ialpha attenuates necrosis and apoptosis following ischemia/reoxygenation in adult cardiomyocyte. J Biol Chem. 2006;281: 38644-38652. (Pubitemid 46041989)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.50
, pp. 38644-38652
-
-
Das, A.1
Smolenski, A.2
Lohmann, S.M.3
Kukreja, R.C.4
-
10
-
-
84858266346
-
Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: Role of hydrogen sulfide
-
Salloum FN, Das A, Samidurai A, Hoke NN, Chau VQ, Ockaili RA, Stasch JP, Kukreja RC. Cinaciguat, a novel activator of soluble guanylate cyclase, protects against ischemia/reperfusion injury: role of hydrogen sulfide. Am J Physiol Heart Circ Physiol. 2012;302:H1347-H1354.
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.302
-
-
Salloum, F.N.1
Das, A.2
Samidurai, A.3
Hoke, N.N.4
Chau, V.Q.5
Ockaili, R.A.6
Stasch, J.P.7
Kukreja, R.C.8
-
11
-
-
20044363270
-
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
-
DOI 10.1038/nm1175
-
Takimoto E, Champion HC, Li M, Belardi D, Ren S, Rodriguez ER, Bedja D, Gabrielson KL, Wang Y, Kass DA. Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy. Nat Med. 2005;11:214-222. (Pubitemid 40321358)
-
(2005)
Nature Medicine
, vol.11
, Issue.2
, pp. 214-222
-
-
Takimoto, E.1
Champion, H.C.2
Li, M.3
Belardi, D.4
Ren, S.5
Rodriguez, E.R.6
Bedja, D.7
Gabrielson, K.L.8
Wang, Y.9
Kass, D.A.10
-
12
-
-
79957755423
-
Phosphodiesterases and cardiac cGMP: Evolving roles and controversies
-
Zhang M, Kass DA. Phosphodiesterases and cardiac cGMP: evolving roles and controversies. Trends Pharmacol Sci. 2011;32:360-365.
-
(2011)
Trends Pharmacol Sci
, vol.32
, pp. 360-365
-
-
Zhang, M.1
Kass, D.A.2
-
13
-
-
77950377332
-
Cardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase i in cardiomyocytes
-
Lukowski R, Rybalkin SD, Loga F, Leiss V, Beavo JA, Hofmann F. Cardiac hypertrophy is not amplified by deletion of cGMP-dependent protein kinase I in cardiomyocytes. Proc Natl Acad Sci USA. 2010;107: 5646-5651.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5646-5651
-
-
Lukowski, R.1
Rybalkin, S.D.2
Loga, F.3
Leiss, V.4
Beavo, J.A.5
Hofmann, F.6
-
14
-
-
34547611337
-
Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility
-
DOI 10.1161/CIRCULATIONAHA.106.655266, PII 0000301720070717000006
-
Nagendran J, Archer SL, Soliman D, Gurtu V, Moudgil R, Haromy A, St Aubin C, Webster L, Rebeyka IM, Ross DB, Light PE, Dyck JR, Michelakis ED. Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility. Circulation. 2007;116:238-248. (Pubitemid 47196559)
-
(2007)
Circulation
, vol.116
, Issue.3
, pp. 238-248
-
-
Nagendran, J.1
Archer, S.L.2
Soliman, D.3
Gurtu, V.4
Moudgil, R.5
Haromy, A.6
St. Aubin, C.7
Webster, L.8
Rebeyka, I.M.9
Ross, D.B.10
Light, P.E.11
Dyck, J.R.B.12
Michelakis, E.D.13
-
15
-
-
78649715496
-
Myocardial remodeling is controlled by myocyte-targeted gene regulation of phosphodiesterase type 5
-
Zhang M, Takimoto E, Hsu S, Lee DI, Nagayama T, Danner T, Koitabashi N, Barth AS, Bedja D, Gabrielson KL, Wang Y, Kass DA. Myocardial remodeling is controlled by myocyte-targeted gene regulation of phosphodiesterase type 5. J Am Coll Cardiol. 2010;56:2021-2030.
-
(2010)
J Am Coll Cardiol
, vol.56
, pp. 2021-2030
-
-
Zhang, M.1
Takimoto, E.2
Hsu, S.3
Lee, D.I.4
Nagayama, T.5
Danner, T.6
Koitabashi, N.7
Barth, A.S.8
Bedja, D.9
Gabrielson, K.L.10
Wang, Y.11
Kass, D.A.12
-
16
-
-
79958039214
-
Mitigation of the progression of heart failure with sildenafil involves inhibition of RhoA/Rho-kinase pathway
-
Chau VQ, Salloum FN, Hoke NN, Abbate A, Kukreja RC. Mitigation of the progression of heart failure with sildenafil involves inhibition of RhoA/Rho-kinase pathway. Am J Physiol Heart Circ Physiol. 2011;300: H2272-H2279.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.300
-
-
Chau, V.Q.1
Salloum, F.N.2
Hoke, N.N.3
Abbate, A.4
Kukreja, R.C.5
-
17
-
-
70349085833
-
CGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardium
-
Vandeput F, Krall J, Ockaili R, Salloum FN, Florio V, Corbin JD, Francis SH, Kukreja RC, Movsesian MA. cGMP-hydrolytic activity and its inhibition by sildenafil in normal and failing human and mouse myocardium. J Pharmacol Exp Ther. 2009;330:884-891.
-
(2009)
J Pharmacol Exp Ther
, vol.330
, pp. 884-891
-
-
Vandeput, F.1
Krall, J.2
Ockaili, R.3
Salloum, F.N.4
Florio, V.5
Corbin, J.D.6
Francis, S.H.7
Kukreja, R.C.8
Movsesian, M.A.9
-
18
-
-
21144435779
-
Pharmacological preconditioning with sildenafil: Basic mechanisms and clinical implications
-
DOI 10.1016/j.vph.2005.02.010, PII S1537189105000625, Pharmacological Preconditioning: Potential New Treatment Modalities for the Ischemic Myocardium
-
Kukreja RC, Salloum F, Das A, Ockaili R, Yin C, Bremer YA, Fisher PW, Wittkamp M, Hawkins J, Chou E, Kukreja AK, Wang X, Marwaha VR, Xi L. Pharmacological preconditioning with sildenafil: basic mechanisms and clinical implications. Vascul Pharmacol. 2005;42:219-232. (Pubitemid 40726325)
-
(2005)
Vascular Pharmacology
, vol.42
, Issue.5-6
, pp. 219-232
-
-
Kukreja, R.C.1
Salloum, F.2
Das, A.3
Ockaili, R.4
Yin, C.5
Bremer, Y.A.6
Fisher, P.W.7
Wittkamp, M.8
Hawkins, J.9
Chou, E.10
Kukreja, A.K.11
Wang, X.12
Marwaha, V.R.13
Xi, L.14
-
19
-
-
20944445197
-
Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load
-
DOI 10.1172/JCI200521968
-
Takimoto E, Champion HC, Li M, Ren S, Rodriguez ER, Tavazzi B, Lazzarino G, Paolocci N, Gabrielson KL, Wang Y, Kass DA. Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load. J Clin Invest. 2005; 115:1221-1231. (Pubitemid 40629040)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.5
, pp. 1221-1231
-
-
Takimoto, E.1
Champion, H.C.2
Li, M.3
Ren, S.4
Rodriguez, E.R.5
Tavazzi, B.6
Lazzarino, G.7
Paolocci, N.8
Gabrielson, K.L.9
Wang, Y.10
Kass, D.A.11
-
20
-
-
84865275375
-
Pathological cardiac hypertrophy alters intracellular targeting of Phosphodiesterase-5 from nitric oxide synthase-3 to natriuretic peptide signaling
-
Zhang M, Takimoto E, Lee D, Santos CXC, Nakamura T, Hsu S, Jiang A, Nagayama T, Bedja D, Yuan Y, Eaton P, Shah AM, Kass DA. Pathological cardiac hypertrophy alters intracellular targeting of Phosphodiesterase-5 from nitric oxide synthase-3 to natriuretic peptide signaling. Circulation. 2012;126:942-951.
-
(2012)
Circulation
, vol.126
, pp. 942-951
-
-
Zhang, M.1
Takimoto, E.2
Lee, D.3
Santos, C.X.C.4
Nakamura, T.5
Hsu, S.6
Jiang, A.7
Nagayama, T.8
Bedja, D.9
Yuan, Y.10
Eaton, P.11
Shah, A.M.12
Kass, D.A.13
-
21
-
-
34247160943
-
Inducible nitric oxide synthase deficiency protects the heart from systolic overload-induced ventricular hypertrophy and congestive heart failure
-
DOI 10.1161/01.RES.0000264081.78659.45
-
Zhang P, Xu X, Hu X, van Deel ED, Zhu G, Chen Y. Inducible nitric oxide synthase deficiency protects the heart from systolic overloadinduced ventricular hypertrophy and congestive heart failure. Circ Res. 2007;100:1089-1098. (Pubitemid 46598934)
-
(2007)
Circulation Research
, vol.100
, Issue.7
, pp. 1089-1098
-
-
Zhang, P.1
Xu, X.2
Hu, X.3
Van Deel, E.D.4
Zhu, G.5
Chen, Y.6
|