PPARδ reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice by regulating extracellular matrix homeostasis and inflammatory responses

International Journal of Cardiology

Volumn 174, Issue 1, 2014, Pages 43-50

  Kim, Hyun Joon ^b   Hwang, Jung Seok ^a   Kim, Hyo Jung ^a,e   Kim, Gyeongwha ^b   Kang, Eun Sil ^a   Ham, Sun Ah ^a   Yoo, Taesik ^a   Paek, Kyung Shin ^c   Yabe Nishimura, Chihiro ^d   Seo, Han Geuk ^a  

^a Konkuk University   (South Korea)

^b Gyeongsang National University School of Medicine   (South Korea)

^c Semyung University   (South Korea)

^d KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^e Yonsei University College of Medicine   (South Korea)

Author keywords

Abdominal aortic aneurysms; Angiotensin II; Extracellular matrix proteins; Gene expression; Peroxisome proliferator activated receptor

Indexed keywords

ANGIOTENSIN II; APOLIPOPROTEIN E; COLLAGEN TYPE 1; COLLAGEN TYPE 3; ELASTIN; FIBRONECTIN; GELATINASE A; INDUCIBLE NITRIC OXIDE SYNTHASE; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; SCLEROPROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TRANSFORMING GROWTH FACTOR BETA1; [2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID;

ABDOMINAL AORTA ANEURYSM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AORTA DISSECTION; AORTA RUPTURE; APOPTOSIS; ARTICLE; BLOOD VESSEL DIAMETER; CELL LOSS; CONTROLLED STUDY; DRUG EFFECT; ENZYME REPRESSION; EXTRACELLULAR MATRIX; HYPOBETALIPOPROTEINEMIA; INFLAMMATION; MACROPHAGE MIGRATION INHIBITION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN HOMEOSTASIS; PROTEIN SYNTHESIS REGULATION; SYSTOLIC BLOOD PRESSURE; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; AORTIC ANEURYSM, ABDOMINAL; DEFICIENCY; DRUG EFFECTS; HOMEOSTASIS; INFUSION PUMP; PHYSIOLOGY;

ANGIOTENSIN II; ANIMALS; AORTIC ANEURYSM, ABDOMINAL; APOLIPOPROTEINS E; EXTRACELLULAR MATRIX; HOMEOSTASIS; INFLAMMATION; INFUSION PUMPS; MALE; MICE; PPAR DELTA;

EID: 84901197125     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2014.03.138     Document Type: Article

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