The association between in vivo physicochemical changes and inflammatory responses against alginate based microcapsules

Biomaterials

Volumn 33, Issue 22, 2012, Pages 5552-5559

  De Vos, Paul ^a   Spasojevic, Milica ^b   De Haan, Bart J ^a   Faas, Marijke M ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Alginate; Bioartificial pancreas; Inflammation; Microencapsulation; XPS (X ray photoelectron spectroscopy)

Indexed keywords

ALGINATE CAPSULES; ALGINATE-BASED MICROCAPSULES; BIO-ARTIFICIAL PANCREAS; IMMUNO-ISOLATION; IMMUNOCYTOCHEMISTRY; IN-VIVO; INFLAMMATION; INFLAMMATORY RESPONSE; LIVING CELL; MICROENCAPSULATION; MICROENVIRONMENTS; NITROGEN CONTENT; PHYSICO-CHEMICAL CHANGES; PHYSICOCHEMICAL PROPERTY;

ALGINATE; PHOTOELECTRONS; X RAY PHOTOELECTRON SPECTROSCOPY; ZETA POTENTIAL;

ENCAPSULATION;

ALGINIC ACID; NITROGEN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; IMPLANTATION; IN VIVO STUDY; INFLAMMATION; MALE; MICROCAPSULE; MICROENVIRONMENT; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; X RAY PHOTOELECTRON SPECTROSCOPY; ZETA POTENTIAL; ANIMAL; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG EFFECT; HARDNESS; IMMUNOLOGY; INNATE IMMUNITY; MATERIALS TESTING; RAT STRAIN; SURFACE PROPERTY;

ALGINATES; ANIMALS; CAPSULES; HARDNESS; IMMUNITY, INNATE; INFLAMMATION; MALE; MATERIALS TESTING; RATS, INBRED STRAINS; SURFACE PROPERTIES;

EID: 84861225861     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.04.039     Document Type: Article

References (60)

1. Lim F., Sun A.M. Microencapsulated islets as bioartificial endocrine pancreas. Science 1980, 210:908-910.
2. Hasse C., Klock G., Schlosser A., Zimmermann U., Rothmund M. Parathyroid allotransplantation without immunosuppression. Lancet 1997, 350:1296-1297.
3. Basta G., Montanucci P., Luca G., Boselli C., Noya G., Barbaro B., et al. Long-term metabolic and immunological follow-up of nonimmunosuppressed patients with type 1 diabetes treated with microencapsulated islet allografts: four cases. Diabetes Care 2011, 34:2406-2409.
4. Basta G., Calafiore R. Immunoisolation of pancreatic islet grafts with no recipient's immunosuppression: actual and future perspectives. Curr Diab Rep 2011, 11:384-391.
5. Montanucci P., Pennoni I., Pescara T., Blasi P., Bistoni G., Basta G., et al. The functional performance of microencapsulated human pancreatic islet-derived precursor cells. Biomaterials 2011, 32:9254-9262.
6. Fritschy W.M., De Vos P., Groen H., Klatter F.A., Pasma A., Wolters G.H., et al. The capsular overgrowth on microencapsulated pancreatic islet grafts in streptozotocin and autoimmune diabetic rats. Transpl Int 1994, 7:264-271.
7. Calafiore R., Basta G., Luca G., Calvitti M., Calabrese G., Racanicchi L., et al. Grafts of microencapsulated pancreatic islet cells for the therapy of diabetes mellitus in non-immunosuppressed animals. Biotechnol Appl Biochem 2004, 39:159-164.
8. Soon Shiong P., Feldman E., Nelson R., Komtebedde J., Smidsrod O., Skjak Braek G., et al. Successful reversal of spontaneous diabetes in dogs by intraperitoneal microencapsulated islets. Transplantation 1992, 54:769-774.
9. Sun Y., Ma X., Zhou D., Vacek I., Sun A.M. Normalization of diabetes in spontaneously diabetic cynomologus monkeys by xenografts of microencapsulated porcine islets without immunosuppression. J Clin Invest 1996, 98:1417-1422.
10. De Vos P., Andersson A., Tam S.K., Faas M.M., Halle J.P. Advances and barriers in mammalian cell encapsulation for treatment of diabetes. Immunol Endocr Metab Agents Med Chem 2006, 139-153.
11. Basta G., Sarchielli P., Luca G., Racanicchi L., Nastruzzi C., Guido L., et al. Optimized parameters for microencapsulation of pancreatic islet cells: an in vitro study clueing on islet graft immunoprotection in type 1 diabetes mellitus. Transpl Immunol 2004, 13:289-296.
12. Tam S.K., Bilodeau S., Dusseault J., Langlois G., Halle J.P., Yahia L.H. Biocompatibility and physicochemical characteristics of alginate-polycation microcapsules. Acta Biomater 2011, 7:1683-1692.
13. Orive G., Tam S.K., Pedraz J.L., Halle J.P. Biocompatibility of alginate-poly-l-lysine microcapsules for cell therapy. Biomaterials 2006, 27:3691-3700.
14. Dusseault J., Tam S.K., Menard M., Polizu S., Jourdan G., Yahia L., et al. Evaluation of alginate purification methods: effect on polyphenol, endotoxin, and protein contamination. J Biomed Mater Res A 2006, 76:243-251.
15. Ponce S., Orive G., Hernandez R., Gascon A.R., Pedraz J.L., De Haan B.J., et al. Chemistry and the biological response against immunoisolating alginate-polycation capsules of different composition. Biomaterials 2006, 27:4831-4839.
16. Tam S.K., de Haan B.J., Faas M.M., Halle J.P., Yahia L., de Vos P. Adsorption of human immunoglobulin to implantable alginate-poly-L-lysine microcapsules: effect of microcapsule composition. J Biomed Mater Res A 2009, 89:609-615.
17. Santos E., Zarate J., Orive G., Hernandez R.M., Pedraz J.L. Biomaterials in cell microencapsulation. Adv Exp Med Biol 2010, 670:5-21.
18. de Vos P., Bucko M., Gemeiner P., Navratil M., Svitel J., Faas M., et al. Multiscale requirements for bioencapsulation in medicine and biotechnology. Biomaterials 2009, 30:2559-2570.
19. Lacik I. Polymer chemistry in diabetes treatment by encapsulation to study islet potency: engraftment and function. Aust J Chem 2006, 59:508-524.
20. De Vos P., Faas M.M., Strand B., Calafiore R. Alginate-based microcapsules for immunoisolation of pancreatic islets. Biomaterials 2006, 27:5603-5617.
21. Tam S.K., Dusseault J., Bilodeau S., Langlois G., Halle J.P., Yahia L. Factors influencing alginate gel biocompatibility. J Biomed Mater Res A 2011, 98:40-52.
22. Ludwig B.F., Rotem A., Schmid J., Weir G.C., Colton C.K., Brendel M.D., et al. Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist. Proc Natl Acad Sci U S A 2012, 109:5022-5027.
23. Haug A. Alginic acid. isolation and fractionation with potassium chloride and manganous ions. Methods in carbohydrate chemistry 1965, 69-72. Academic Press, New York. R.L. Whistler, J.N. Bemiller, M.L. Wolfron (Eds.).
24. Staub A.M. Removal of proteins. Methods in carbohydrate chemistry 1965, 163-168. Academic Press, New York. R.L. Whistler, J.N. Bemiller, M.L. Wolfrom (Eds.).
25. Haug A., Larsen B. The solibility of alginate at low pH. Acta Chem Scand 1963, 17:1653-1662.
26. Haug A., Myklestad S., Larsen B., Smidsrod O. Correlation between chemical structure and physical properties of alginates. Acta Chem Scand 1967, 21:768-778.
27. De Vos P., Wolters G.H.J., Van Schilfgaarde R. Possible relationship between fibrotic overgrowth of alginate- polylysine-alginate microencapsulated pancreatic islets and the microcapsule integrity. Transplant Proc 1994, 26:782-783.
28. Thu B., Bruheim P., Espevik T., Smidrod O., Soon-Shiong P., Skjak-Braek G. Alginate polycation microcapsules. I. interaction between alginate and polycation. Biomaterials 1996, 17:1031-1040.
29. Thu B., Bruheim P., Espevik T., Smidrod O., Soon-Shiong P., Skjak-Break G. Alginate polycation microcapsules II. some functional properties. Biomaterials 1996, 17:1069-1079.
30. De Vos P., De Haan B.J., Van Schilfgaarde R. Upscaling the production of encapsulated islets. Biomaterials 1997, 18:1085-1090.
31. De Haan B.J., Faas M.M., De Vos P. Factors influencing insulin secretion from encapsulated islets. Cell Transplant 2003, 12:617-625.
32. Tatarkiewicz K., Garcia M., Omer A., Van Schilfgaarde R., Weir G.C., De Vos P. C-peptide responses after meal challenge in mice transplanted with microencapsulated rat islets. Diabetologia 2001, 44:646-653.
33. Tam S.K., Dusseault J., Polizu S., Menard M., Halle J.P., Yahia L. Physicochemical model of alginate-poly-L-lysine microcapsules defined at the micrometric/nanometric scale using ATR-FTIR, XPS, and ToF-SIMS. Biomaterials 2005, 26:6950-6961.
34. De Vos P., Van Hoogmoed C.G., Busscher H.J. Chemistry and biocompatibility of alginate-PLL capsules for immunoprotection of mammalian cells. J Biomed Mater Res A 2002, 60:252-259.
35. De Vos P., Van Hoogmoed C.G., De Haan B.J., Busscher H.J. Tissue responses against immunoisolating alginate-PLL capsules in the immediate posttransplant period. J Biomed Mater Res A 2002, 62:430-437.
36. De Vos P., De Haan B.J., Kamps J.A., Faas M.M., Kitano T. Zeta-potentials of alginate-PLL capsules: a predictive measure for biocompatibility?. J Biomed Mater Res A 2007, 80:813-819.
37. De Haan B.J., van Goor H., De Vos P. Processing of immunoisolated pancreatic islets: implications for histological analyses of hydrated tissue. Biotechniques 2002, 32:612-619.
38. De Vos P., Smedema I., van Goor H., Moes H., van Zanten J., Netters S., et al. Association between macrophage activation and function of micro-encapsulated rat islets. Diabetologia 2003, 46:666-673.
39. Dijkstra C.D., Dopp E.A., Joling P., Kraal G. The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3. Immunology 1985, 54:589-599.
40. Deenen G.J., Hunt S.V., Opstelten D. A stathmokinetic study of B lymphocytopoiesis in rat bone marrow: proliferation of cells containing cytoplasmic mu-chains, terminal deoxynucleotidyl transferase and carrying HIS24 antigen. J Immunol 1987, 139:702-710.
41. Huning T., Wallny H.J., Hartly J., Lawetsky A., Tiefenthaler G. A monoclonal antibody to a constant region of the rat TCR that induces T-cell activation. J Exp Med 1989, 169:73-78.
42. De Vos P., Van Hoogmoed C.G., van Zanten J., Netter S., Strubbe J.H., Busscher H.J. Long-term biocompatibility, chemistry, and function of microencapsulated pancreatic islets. Biomaterials 2003, 24:305-312.
43. De Vos P., De Haan B., Van Schilfgaarde R. Effect of the alginate composition on the biocompatibility of alginate-polylysine microcapsules. Biomaterials 1997, 18:273-278.
44. Bunger C.M., Tiefenbach B., Jahnke A., Gerlach C., Freier T., Schmitz K.P., et al. Deletion of the tissue response against alginate-pll capsules by temporary release of co-encapsulated steroids. Biomaterials 2005, 26:2353-2360.
45. Ricci M., Blasi P., Giovagnoli S., Rossi C., Macchiarulo G., Luca G., et al. Ketoprofen controlled release from composite microcapsules for cell encapsulation: effect on post-transplant acute inflammation. J Control Release 2005, 107:395-407.
46. de Haan B.J., Rossi A., Faas M.M., Smelt M.J., Sonvico F., Colombo P., et al. Structural surface changes and inflammatory responses against alginate-based microcapsules after exposure to human peritoneal fluid. J Biomed Mater Res A 2011, 98:394-403.
47. Vandenbossche G.M., Bracke M.E., Cuvelier C.A., Bortier H.E., Mareel M.M., Remon J.P. Host reaction against alginate-polylysine microcapsules containing living cells. J Pharm Pharmacol 1993, 45:121-125.
48. King A., Andersson A., Strand B.L., Lau J., Skjak-Braek G., Sandler S. The role of capsule composition and biologic responses in the function of transplanted microencapsulated islets of langerhans. Transplantation 2003, 76:275-279.
49. King A., Sandler S., Andersson A. The effect of host factors and capsule composition on the cellular overgrowth on implanted alginate capsules. J Biomed Mater Re 2001, 57:374-383.
50. Tang L., Eaton J.W. Inflammatory responses to biomaterials. Am J Clin Pathol 1995, 103:466-471.
51. Tang L., Jennings T.A., Eaton J.W. Mast cells mediate acute inflammatory responses to implanted biomaterials. Proc Natl Acad Sci U S A 1998, 95:8841-8846.
52. Omer A., Keegan M., Czismadia E., De Vos P., Van Rooijen N., Bonner-Weir S., et al. Macrophage depletion improves survival of porcine neonatal pancreatic cell clusters contained in alginate macrocapsules transplanted into rats. Xenotransplantation 2003, 10:240-251.
53. de Groot M., Keizer P.P., De Haan B.J., Schuurs T.A., Leuvenink H.G., Van Schilfgaarde R., et al. Microcapsules and their ability to protect islets against cytokine-mediated dysfunction. Transpl Proc 2001, 33:1711-1712.
54. Hu W.J., Eaton J.W., Tang L. Molecular basis of biomaterial-mediated foreign body reactions. Blood 2001, 98:1231-1238.
55. Van Hoogmoed C.G., Busscher H.J., De Vos P. Fourier transform infrared spectroscopy studies of alginate-PLL capsules with varying compositions. J Biomed Mater Res A 2003, 67A:172-178.
56. De Vos P., van Straaten J.F., Nieuwenhuizen A.G., de Groot M., Ploeg R.J., De Haan B.J., et al. Why do microencapsulated islet grafts fail in the absence of fibrotic overgrowth?. Diabetes 1999, 48:1381-1388.
57. Barthson J., Germano C.M., Moore F., Maida A., Drucker D.J., Marchetti P., et al. Cytokines tumor necrosis factor-alpha and interferon-gamma induce pancreatic beta-cell apoptosis through STAT1-mediated Bim protein activation. J Biol Chem 2011, 286:39632-39643.
58. Ishiyama K., Rawson J., Omori K., Mullen Y. Liver natural killer cells play a role in the destruction of islets after intraportal transplantation. Transplantation 2011, 91:952-960.
59. Wu H., Panakanti R., Li F., Mahato R.I. XIAP gene expression protects beta-cells and human islets from apoptotic cell death. Mol Pharm 2010.
60. De Vos P., De Haan B.J., Pater J., Van Schilfgaarde R. Association between capsule diameter, adequacy of encapsulation, and survival of microencapsulated rat islet allografts. Transplantation 1996, 62:893-899.