Constitutive expression of murine c-FLIP causes autoimmunity in aged mice

Cell Death and Disease

Volumn 5, Issue 4, 2014, Pages

  Ewald, F ^a,b   Annemann, M ^a,b   Pils, M C ^b   Plaza Sirvent, C ^a,b   Neff, F ^c   Erck, C ^b   Reinhold, D ^a   Schmitz, I ^a,b  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Apoptosis; Autoimmunity; C FLIP; CD95

Indexed keywords

AUTOANTIBODY; FAS ANTIGEN; FLICE INHIBITORY PROTEIN; ANTINUCLEAR ANTIBODY; CFLAR PROTEIN, MOUSE; MYELIN OLIGODENDROCYTE GLYCOPROTEIN;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; APOPTOSIS; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; KIDNEY INJURY; LUNG INJURY; LYMPHOCYTE SUBPOPULATION; MOUSE; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SYSTEMIC LUPUS ERYTHEMATOSUS; TISSUE INJURY; TRANSGENIC MOUSE; ANIMAL; B LYMPHOCYTE; BIOSYNTHESIS; C57BL MOUSE; DISEASE COURSE; DISEASE MODEL; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; IMMUNOLOGY; KIDNEY; LUNG; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOID TISSUE; METABOLISM; PATHOLOGY; PHENOTYPE; T LYMPHOCYTE;

AGING; ANIMALS; ANTIBODIES, ANTINUCLEAR; AUTOANTIBODIES; AUTOIMMUNITY; B-LYMPHOCYTES; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; KIDNEY; LUNG; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOID TISSUE; MICE, INBRED C57BL; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; PHENOTYPE; T-LYMPHOCYTES;

EID: 84901068274     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.138     Document Type: Article

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