Overexpression of smooth muscle myosin heavy chain leads to activation of the unfolded protein response and autophagic turnover of thick filament-associated proteins in vascular smooth muscle cells

Journal of Biological Chemistry

Volumn 289, Issue 20, 2014, Pages 14075-14088

  Kwartler, Callie S ^a   Chen, Jiyuan ^a   Thakur, Dhananjay ^b   Li, Shumin ^c   Baskin, Kedryn ^a   Wang, Shanzhi ^a   Wang, Zhao V ^a   Walker, Lori ^d   Hill, Joseph A ^e   Epstein, Henry F ^f   Taegtmeyer, Heinrich ^a   Milewicz, Dianna M ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e UNIVERSITY OF COLORADO   (United States)

^f NONE

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD VESSELS; CELL MEMBRANES; CHAINS; DISSECTION; GENES; MUSCLE; PLANTS (BOTANY); TRANSCRIPTION;

AUTOPHAGIC DEGRADATION; ENDOPLASMIC RETICULUM STRESS; INTRACELLULAR CALCIUM; MYOSIN HEAVY CHAIN; PROTEIN DEGRADATION; SMOOTH MUSCLE CELLS; UNFOLDED PROTEIN RESPONSE; VASCULAR SMOOTH MUSCLE CELLS;

PROTEINS;

CALCIUM ION; CONTRACTILE PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MYOSIN HEAVY CHAIN; MYH11 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FEEDBACK SYSTEM; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; MUSCLE CONTRACTILITY; MYH11 GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TRANSGENE; UNFOLDED PROTEIN RESPONSE; VASCULAR SMOOTH MUSCLE; ANIMAL; CHROMOSOME 16; CHROMOSOME DUPLICATION; CYTOLOGY; GENETICS; METABOLISM; MUSCLE CONTRACTION; PHYSIOLOGY;

ANIMALS; AUTOPHAGY; CALCIUM SIGNALING; CHROMOSOME DUPLICATION; CHROMOSOMES, HUMAN, PAIR 16; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; HUMANS; MICE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; MYOSIN HEAVY CHAINS; UNFOLDED PROTEIN RESPONSE;

EID: 84901051262     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.499277     Document Type: Article

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