Differential effect of the protein synthesis inhibitors puromycin and cycloheximide on vascular smooth muscle cell viability

Journal of Pharmacology and Experimental Therapeutics

Volumn 325, Issue 3, 2008, Pages 824-832

  Croons, Valerie ^a   Martinet, Wim ^a   Herman, Arnold G ^a   De Meyer, Guido R Y ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 12; CYCLOHEXIMIDE; EUKARYOTIC TRANSLATION INITIATION FACTOR 2ALPHA; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR; MESSENGER RNA; PROTEASOME; PUROMYCIN; THAPSIGARGIN; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATHEROMA; ATHEROSCLEROTIC PLAQUE; CAROTID ARTERY; CELL DEATH; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; IN VITRO STUDY; MACROPHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION; RABBIT; RNA SPLICING; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ANIMALS; APOPTOSIS; ATHEROSCLEROSIS; CAROTID ARTERIES; CASPASE 12; CELL LINE; CELL SURVIVAL; CYCLOHEXIMIDE; DIETARY FATS; DNA FRAGMENTATION; DNA-BINDING PROTEINS; HYPERCHOLESTEROLEMIA; MACROPHAGES; MALE; MICE; MUSCLE, SMOOTH, VASCULAR; MYOBLASTS; MYOCYTES, SMOOTH MUSCLE; NUCLEAR PROTEINS; PROTEIN SYNTHESIS INHIBITORS; PUROMYCIN; RABBITS; RNA, MESSENGER;

EID: 44249089745     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.132944     Document Type: Article

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