Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: Underlying mechanisms

Journal of Physiology

Volumn 589, Issue 8, 2011, Pages 2007-2026

  Ochala, Julien ^a   Gustafson, Ann Marie ^a   Diez, Monica Llano ^a   Renaud, Guillaume ^a   Li, Meishan ^a   Aare, Sudhakar ^a   Qaisar, Rizwan ^a   Banduseela, Varuna C ^a   Hedström, Yvette ^a   Tang, Xiaorui ^b   Dworkin, Barry ^a,b   Ford, G Charles ^c   Nair, K Sreekumaran ^c   Perera, Sue ^d   Gautel, Mathias ^d   Larsson, Lars ^a,e  

^a UPPSALA UNIVERSITY   (Sweden)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^c Mayo Clinic   (United States)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUSCLE RING FINGER 1 PROTEIN; MUSCLE RING FINGER 2 PROTEIN; MYOSIN; PROTEASOME; UBIQUITIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DISEASE SEVERITY; DOWN REGULATION; FEMALE; INTENSIVE CARE UNIT; MUSCLE ATROPHY; MUSCLE CELL; MUSCLE FORCE; MYOPATHY; NONHUMAN; PARALYSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; QUADRIPLEGIA; RAT; SEDATION; TRANSCRIPTION REGULATION;

ANALYSIS OF VARIANCE; ANIMALS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; IMMOBILIZATION; INTENSIVE CARE; MUSCLE CONTRACTION; MUSCLE PROTEINS; MUSCLE STRENGTH; MUSCLE, SKELETAL; MUSCULAR ATROPHY; NEUROMUSCULAR BLOCKING AGENTS; PARALYSIS; PHENOTYPE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BIOSYNTHESIS; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION, ARTIFICIAL; RNA, MESSENGER; SKELETAL MUSCLE MYOSINS; TIME FACTORS; TRANSCRIPTION, GENETIC; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; WEIGHT-BEARING;

EID: 79954530526     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2010.202044     Document Type: Article

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