The glutathione peroxidase 1-protein tyrosine phosphatase 1B-protein phosphatase 2A axis: A key determinant of airway inflammation and alveolar destruction

American Journal of Respiratory Cell and Molecular Biology

Volumn 49, Issue 5, 2013, Pages 721-730

  Geraghty, Patrick ^a   Hardigan, Andrew A ^a   Wallace, Alison M ^b   Mirochnitchenko, Oleg ^c   Thankachen, Jincy ^b   Arellanos, Leo ^b   Thompson, Victor ^b   D'Armiento, Jeanine M ^b   Foronjy, Robert F ^a,d  

^a ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d Department of Thoracic Surgery   (United States)

Author keywords

Inflammation; Kinase; Oxidation; Phosphorylation

Indexed keywords

CIGARETTE SMOKE; GLUTATHIONE PEROXIDASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN TYROSINE PHOSPHATASE 1B; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; EMPHYSEMA; ENZYME ACTIVATION; ENZYME ACTIVITY; EPITHELIUM CELL; EUKARYOTIC CELL; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; KNOCKOUT MOUSE; LUNG INJURY; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN FUNCTION; RESPIRATORY TRACT INFLAMMATION; TRANSGENIC MOUSE;

ANIMALS; CASE-CONTROL STUDIES; CELL LINE; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; GLUTATHIONE PEROXIDASE; HUMANS; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, KNOCKOUT; OXIDATION-REDUCTION; OXIDATIVE STRESS; PHOSPHORYLATION; PNEUMONIA; PROTEIN BINDING; PROTEIN PHOSPHATASE 2; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; PULMONARY ALVEOLI; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA; RESPIRATORY MUCOSA; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMOKING; TRANSFECTION;

EID: 84887057461     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2013-0026OC     Document Type: Article

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