-
1
-
-
38849199203
-
Shared principles in NF-kappaβ signaling
-
Hayden MS, Ghosh S. Shared principles in NF-kappaβ signaling. Cell 2008; 132: 344-362.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
2
-
-
2342464085
-
The two NF-kappaB activation pathways and their role in innate and adaptive immunity
-
Bonizzi G, Karin M. The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol 2004; 25: 280-288.
-
(2004)
Trends Immunol
, vol.25
, pp. 280-288
-
-
Bonizzi, G.1
Karin, M.2
-
3
-
-
0031897632
-
NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses
-
Ghosh S, May MJ, Kopp EB. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 1998; 16: 225-260.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
4
-
-
0027168447
-
NF-kappa B controls expression of inhibitor i kappa B alpha: Evidence for an inducible autoregulatory pathway
-
Sun SC, Ganchi PA, Ballard DW, Greene WC. NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway. Science 1993; 259: 1912-1915.
-
(1993)
Science
, vol.259
, pp. 1912-1915
-
-
Sun, S.C.1
Ganchi, P.A.2
Ballard, D.W.3
Greene, W.C.4
-
5
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
Chen G, Goeddel DV. TNF-R1 signaling: A beautiful pathway. Science 2002; 296: 1634-1635.
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
6
-
-
0033595893
-
How NF-kappaB is activated: The role of the IkappaB kinase (IKK) complex
-
Karin M. How NF-kappaB is activated: The role of the IkappaB kinase (IKK) complex. Oncogene 1999; 18: 6867-6874.
-
(1999)
Oncogene
, vol.18
, pp. 6867-6874
-
-
Karin, M.1
-
7
-
-
58149202128
-
Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls
-
Baud V, Karin M. Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls. Nat Rev Drug Discov 2009; 8: 33-40.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 33-40
-
-
Baud, V.1
Karin, M.2
-
8
-
-
33845768987
-
Integrating cell-signalling pathways with NF-kappaB and IKK function
-
Perkins ND. Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol 2007; 8: 49-62.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 49-62
-
-
Perkins, N.D.1
-
9
-
-
23144449789
-
Ubiquitin signalling in the NF-kappaB pathway
-
Chen ZJ. Ubiquitin signalling in the NF-kappaB pathway. Nat Cell Biol 2005; 7: 758-765.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 758-765
-
-
Chen, Z.J.1
-
10
-
-
67650744586
-
The role of ubiquitin in NF-kappaB regulatory pathways
-
Skaug B, Jiang X, Chen ZJ. The role of ubiquitin in NF-kappaB regulatory pathways. Annu Rev Biochem 2009; 78: 769-796.
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 769-796
-
-
Skaug, B.1
Jiang, X.2
Chen, Z.J.3
-
11
-
-
33645977821
-
Ubiquitin TAK1 and IKK: Is there a connection?
-
Chen ZJ, Bhoj V, Seth RB. Ubiquitin, TAK1 and IKK: is there a connection? Cell Death Differ 2006; 13: 687-692.
-
(2006)
Cell Death Differ
, vol.13
, pp. 687-692
-
-
Chen, Z.J.1
Bhoj, V.2
Seth, R.B.3
-
12
-
-
39049183044
-
Regulation and function of IKK and IKK-related kinases
-
Hacker H, Karin M. Regulation and function of IKK and IKK-related kinases. Sci STKE 2006; 2006: re13.
-
(2006)
Sci STKE
, vol.2006
-
-
Hacker, H.1
Karin, M.2
-
13
-
-
40749139505
-
Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of ikappabalpha kinase
-
Windheim M, Stafford M, Peggie M, Cohen P. Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase. Mol Cell Biol 2008; 28: 1783-1791.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 1783-1791
-
-
Windheim, M.1
Stafford, M.2
Peggie, M.3
Cohen, P.4
-
14
-
-
0030004897
-
Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity
-
Chen ZJ, Parent L, Maniatis T. Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity. Cell 1996; 84: 853-862.
-
(1996)
Cell
, vol.84
, pp. 853-862
-
-
Chen, Z.J.1
Parent, L.2
Maniatis, T.3
-
15
-
-
0037084504
-
All TRAFs are not created equal: Common and distinct molecular mechanisms of TRAF-mediated signal transduction
-
Chung JY, Park YC, Ye H, Wu H. All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction. J Cell Sci 2002; 115: 679-688.
-
(2002)
J Cell Sci
, vol.115
, pp. 679-688
-
-
Chung, J.Y.1
Park, Y.C.2
Ye, H.3
Wu, H.4
-
16
-
-
0033725155
-
The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
-
Devin A, Cook A, Lin Y, Rodriguez Y, Kelliher M, Liu Z. The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation. Immunity 2000; 12: 419-429.
-
(2000)
Immunity
, vol.12
, pp. 419-429
-
-
Devin, A.1
Cook, A.2
Lin, Y.3
Rodriguez, Y.4
Kelliher, M.5
Liu, Z.6
-
17
-
-
0035021123
-
The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF
-
Devin A, Lin Y, Yamaoka S, Li Z, Karin M, Liu Z. The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF. Mol Cell Biol 2001; 21: 3986-3994.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3986-3994
-
-
Devin, A.1
Lin, Y.2
Yamaoka, S.3
Li, Z.4
Karin, M.5
Liu, Z.6
-
18
-
-
33646034316
-
Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
-
Ea CK, Deng L, Xia ZP, Pineda G, Chen ZJ. Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. Mol Cell 2006; 22: 245-257.
-
(2006)
Mol Cell
, vol.22
, pp. 245-257
-
-
Ea, C.K.1
Deng, L.2
Xia, Z.P.3
Pineda, G.4
Chen, Z.J.5
-
19
-
-
33645703930
-
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]
-
Wu CJ, Conze DB, Li T, Srinivasula SM, Ashwell JD. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]. Nat Cell Biol 2006; 8: 398-406.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 398-406
-
-
Wu, C.J.1
Conze, D.B.2
Li, T.3
Srinivasula, S.M.4
Ashwell, J.D.5
-
20
-
-
11144289688
-
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
-
Aßbott DW, Wilkins A, Asara JM, Cantley LC. The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO. Curr Biol 2004; 14: 2217-2227.
-
(2004)
Curr Biol
, vol.14
, pp. 2217-2227
-
-
Aßbott, D.W.1
Wilkins, A.2
Asara, J.M.3
Cantley, L.C.4
-
21
-
-
0345826149
-
Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO
-
Zhou H, Wertz I, O'Rourke K, Ultsch M, Seshagiri S, Eby M et al. Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO. Nature 2004; 427: 167-171.
-
(2004)
Nature
, vol.427
, pp. 167-171
-
-
Zhou, H.1
Wertz, I.2
O'rourke, K.3
Ultsch, M.4
Seshagiri, S.5
Eby, M.6
-
22
-
-
0345826130
-
Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity
-
Prajapati S, Verma U, Yamamoto Y, Kwak YT, Gaynor RB. Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity. J Biol Chem 2004; 279: 1739-1746.
-
(2004)
J Biol Chem
, vol.279
, pp. 1739-1746
-
-
Prajapati, S.1
Verma, U.2
Yamamoto, Y.3
Kwak, Y.T.4
Gaynor, R.B.5
-
23
-
-
54049115864
-
Identification of PP2A as a crucial regulator of the NF-kappaB feedback loop: Its inhibition by UVB turns NF-kappaB into a pro-apoptotic factor
-
Barisic S, Strozyk E, Peters N, Walczak H, Kulms D. Identification of PP2A as a crucial regulator of the NF-kappaB feedback loop: its inhibition by UVB turns NF-kappaB into a pro-apoptotic factor. Cell Death Differ 2008; 15: 1681-1690.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1681-1690
-
-
Barisic, S.1
Strozyk, E.2
Peters, N.3
Walczak, H.4
Kulms, D.5
-
24
-
-
42449137850
-
Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1
-
Li HY, Liu H, Wang CH, Zhang JY, Man JH, Gao YF et al. Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1. Nat Immunol 2008; 9: 533-541.
-
(2008)
Nat Immunol
, vol.9
, pp. 533-541
-
-
Li, H.Y.1
Liu, H.2
Wang, C.H.3
Zhang, J.Y.4
Man, J.H.5
Gao, Y.F.6
-
25
-
-
78650915537
-
Deubiquitinases in the regulation of NF-kappaβ signaling
-
Harhaj EW, Dixit VM. Deubiquitinases in the regulation of NF-kappaβ signaling. Cell Res 21: 22-39.
-
Cell Res
, vol.21
, pp. 22-39
-
-
Harhaj, E.W.1
Dixit, V.M.2
-
26
-
-
65249186662
-
Polyubiquitin binding and disassembly by deubiquitinating enzymes
-
Reyes-Turcu FE, Wilkinson KD. Polyubiquitin binding and disassembly by deubiquitinating enzymes. Chem Rev 2009; 109: 1495-1508.
-
(2009)
Chem Rev
, vol.109
, pp. 1495-1508
-
-
Reyes-Turcu, F.E.1
Wilkinson, K.D.2
-
27
-
-
84858725584
-
Regulation of NF-kappaB by deubiquitinases
-
Harhaj EW, Dixit VM. Regulation of NF-kappaB by deubiquitinases. Immunol Rev 246: 107-124.
-
Immunol Rev
, vol.246
, pp. 107-124
-
-
Harhaj, E.W.1
Dixit, V.M.2
-
28
-
-
0034730713
-
Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice
-
Lee EG, Boone DL, Chai S, Libby SL, Chien M, Lodolce JP et al. Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice. Science 2000; 289: 2350-2354.
-
(2000)
Science
, vol.289
, pp. 2350-2354
-
-
Lee, E.G.1
Boone, D.L.2
Chai, S.3
Libby, S.L.4
Chien, M.5
Lodolce, J.P.6
-
29
-
-
68149139538
-
The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology
-
Vereecke L, Beyaert R, van Loo G. The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology. Trends Immunol 2009; 30: 383-391.
-
(2009)
Trends Immunol
, vol.30
, pp. 383-391
-
-
Vereecke, L.1
Beyaert, R.2
Van Loo, G.3
-
30
-
-
35548974703
-
Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD
-
Wright A, Reiley WW, Chang M, Jin W, Lee AJ, Zhang M et al. Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD. Dev Cell 2007; 13: 705-716.
-
(2007)
Dev Cell
, vol.13
, pp. 705-716
-
-
Wright, A.1
Reiley, W.W.2
Chang, M.3
Jin, W.4
Lee, A.J.5
Zhang, M.6
-
31
-
-
33750598021
-
Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLDdeficient mice
-
Zhang J, Stirling B, Temmerman ST, Ma CA, Fuss IJ, Derry JM et al. Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLDdeficient mice. J Clin Invest 2006; 116: 3042-3049.
-
(2006)
J Clin Invest
, vol.116
, pp. 3042-3049
-
-
Zhang, J.1
Stirling, B.2
Temmerman, S.T.3
Ma, C.A.4
Fuss, I.J.5
Derry, J.M.6
-
32
-
-
70849100656
-
HSCARG inhibits activation of NF-kappaB by interacting with IkappaB kinase-beta
-
Gan Q, Li T, Hu B, Lian M, Zheng X. HSCARG inhibits activation of NF-kappaB by interacting with IkappaB kinase-beta. J Cell Sci 2009; 122: 4081-4088.
-
(2009)
J Cell Sci
, vol.122
, pp. 4081-4088
-
-
Gan, Q.1
Li, T.2
Hu, B.3
Lian, M.4
Zheng, X.5
-
33
-
-
36248944103
-
Ribosomal protein S3: A KH domain subunit in NF-kappaB complexes that mediates selective gene regulation
-
Wan F, Anderson DE, Barnitz RA, Snow A, Bidere N, Zheng L et al. Ribosomal protein S3: A KH domain subunit in NF-kappaB complexes that mediates selective gene regulation. Cell 2007; 131: 927-939.
-
(2007)
Cell
, vol.131
, pp. 927-939
-
-
Wan, F.1
Anderson, D.E.2
Barnitz, R.A.3
Snow, A.4
Bidere, N.5
Zheng, L.6
-
34
-
-
0141621240
-
A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha
-
Tang ED, Wang CY, Xiong Y, Guan KL. A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha. J Biol Chem 2003; 278: 37297-37305.
-
(2003)
J Biol Chem
, vol.278
, pp. 37297-37305
-
-
Tang, E.D.1
Wang, C.Y.2
Xiong, Y.3
Guan, K.L.4
-
35
-
-
2342629277
-
The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes
-
Sun L, Deng L, Ea CK, Xia ZP, Chen ZJ. The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes. Mol Cell 2004; 14: 289-301.
-
(2004)
Mol Cell
, vol.14
, pp. 289-301
-
-
Sun, L.1
Deng, L.2
Ea, C.K.3
Xia, Z.P.4
Chen, Z.J.5
-
36
-
-
59649103156
-
Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation
-
Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K et al. Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation. Nat Cell Biol 2009; 11: 123-132.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 123-132
-
-
Tokunaga, F.1
Sakata, S.2
Saeki, Y.3
Satomi, Y.4
Kirisako, T.5
Kamei, K.6
-
37
-
-
80053953002
-
Linear ubiquitination in NF-kappaβ signaling and inflammation: What we do understand and what we do not
-
Verhelst K, Verstrepen L, Carpentier I, Beyaert R. Linear ubiquitination in NF-kappaβ signaling and inflammation: what we do understand and what we do not. Biochem Pharmacol 2011; 82: 1057-1065.
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 1057-1065
-
-
Verhelst, K.1
Verstrepen, L.2
Carpentier, I.3
Beyaert, R.4
-
38
-
-
67650531180
-
HSCARG regulates NF-kappaB activation by promoting the ubiquitination of RelA or COMMD1
-
Lian M, Zheng X. HSCARG regulates NF-kappaB activation by promoting the ubiquitination of RelA or COMMD1. J Biol Chem 2009; 284: 17998-18006.
-
(2009)
J Biol Chem
, vol.284
, pp. 17998-18006
-
-
Lian, M.1
Zheng, X.2
-
39
-
-
65349175161
-
HSV ICP0 recruits USP7 to modulate TLR-mediated innate response
-
Daubeuf S, Singh D, Tan Y, Liu H, Federoff HJ, Bowers WJ et al. HSV ICP0 recruits USP7 to modulate TLR-mediated innate response. Blood 2009; 113: 3264-3275.
-
(2009)
Blood
, vol.113
, pp. 3264-3275
-
-
Daubeuf, S.1
Singh, D.2
Tan, Y.3
Liu, H.4
Federoff, H.J.5
Bowers, W.J.6
-
40
-
-
78650130030
-
The ubiquitin E3 ligase RAUL negatively regulates type i interferon through ubiquitination of the transcription factors IRF7 and IRF3
-
Yu Y, Hayward GS. The ubiquitin E3 ligase RAUL negatively regulates type i interferon through ubiquitination of the transcription factors IRF7 and IRF3. Immunity 2010; 33: 863-877.
-
(2010)
Immunity
, vol.33
, pp. 863-877
-
-
Yu, Y.1
Hayward, G.S.2
-
41
-
-
84872202679
-
Deubiquitination of NF-kappaB by ubiquitin-specific protease-7 promotes transcription
-
Colleran A, Collins PE, O'Carroll C, Ahmed A, Mao X, McManus B et al. Deubiquitination of NF-kappaB by ubiquitin-specific protease-7 promotes transcription. Proc Natl Acad Sci USA 2013; 110: 618-623.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 618-623
-
-
Colleran, A.1
Collins, P.E.2
O'carroll, C.3
Ahmed, A.4
Mao, X.5
McManus, B.6
|