The effect of ketamine on optical and electrical characteristics of spreading depolarizations in gyrencephalic swine cortex

Neuropharmacology

Volumn 84, Issue , 2014, Pages 52-61

  Sánchez Porras, Renán ^a   Santos, Edgar ^a   Schöll, Michael ^a,b   Stock, Christian ^b   Zheng, Zelong ^a   Schiebel, Patrick ^a   Orakcioglu, Berk ^a   Unterberg, Andreas W ^a   Sakowitz, Oliver W ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Electrocorticography (ECoG); Intrinsic optical signal (IOS) imaging; Ketamine; NMDA receptor blocker; Spreading depolarization (SD)

Indexed keywords

KETAMINE; AMINO ACID RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BOLUS INJECTION; BRAIN CORTEX; BRAIN REGION; CONTINUOUS INFUSION; CONTROLLED STUDY; DEPOLARIZATION; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MEGADOSE; ELECTROCORTICOGRAPHY; FLUORESCENCE IMAGING; GYRENCEPHALIC CORTEX; HYPEREMIA; LOW DRUG DOSE; MALE; NEUROPHARMACOLOGY; NONHUMAN; PRIORITY JOURNAL; RESPONSE TIME; SIGNAL DETECTION; SPREADING DEPOLARIZATION; STIMULUS RESPONSE; ANIMAL; BRAIN CIRCULATION; DISEASE MODEL; DRUG EFFECTS; ELECTROENCEPHALOGRAPHY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPREADING CORTICAL DEPRESSION; SWINE; TIME; VIDEORECORDING;

ANIMALS; CEREBRAL CORTEX; CEREBROVASCULAR CIRCULATION; CORTICAL SPREADING DEPRESSION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROENCEPHALOGRAPHY; EXCITATORY AMINO ACID ANTAGONISTS; HYPEREMIA; KETAMINE; MALE; OPTICAL IMAGING; SWINE; TIME FACTORS; VIDEO RECORDING;

EID: 84901048090     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.04.018     Document Type: Article

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