Sustained NMDA receptor activation by spreading depolarizations can initiate excitotoxic injury in metabolically compromised neurons

Journal of Physiology

Volumn 590, Issue 22, 2012, Pages 5877-5893

  Aiba, Isamu ^a   Shuttleworth, C William ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL TISSUE; ARTICLE; BRAIN INJURY; BRAIN NERVE CELL; BRAIN SLICE; CALCIUM CELL LEVEL; CELL IMAGING; CONTROLLED STUDY; DENDRITE; DENDRITIC IONIC DYSHOMEOSTASIS; ELECTROPHYSIOLOGY; ENERGY METABOLISM; EVOKED RESPONSE; EXCITATORY POSTSYNAPTIC POTENTIAL; EXCITOTOXICITY; GLUTAMATE RELEASE; HIPPOCAMPAL CA1 REGION; IMAGING; MALE; MOUSE; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE EXCITABILITY; NEUROTRANSMITTER RELEASE; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; SPREADING DEPOLARIZATION;

ANIMALS; CA1 REGION, HIPPOCAMPAL; CALCIUM; CALCIUM SIGNALING; CORTICAL SPREADING DEPRESSION; DENDRITES; EXCITATORY POSTSYNAPTIC POTENTIALS; GLUTAMIC ACID; MICE; MICE, INBRED C57BL; RECEPTORS, N-METHYL-D-ASPARTATE; SODIUM AZIDE; STRESS, PHYSIOLOGICAL;

EID: 84869745918     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2012.234476     Document Type: Article

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