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Volumn 5, Issue MAR, 2014, Pages

Thyroid hormones, T3 and T4, in the brain

Author keywords

Brain; Coregulator; Deiodinase 2; Thyroid hormone receptor

Indexed keywords

HORMONE RECEPTOR STIMULATING AGENT; LIOTHYRONINE; MONOCARBOXYLATE TRANSPORTER 8; ORGANIC ANION TRANSPORTER F; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR BINDING PROTEIN; PROTIRELIN; STEROID RECEPTOR COACTIVATOR 1; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR BETA; THYROTROPIN; THYROXINE; THYROXINE DEIODINASE;

EID: 84901036696     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2014.00040     Document Type: Review
Times cited : (131)

References (61)
  • 1
    • 10344260802 scopus 로고    scopus 로고
    • Role of thyroid hormone during early brain development
    • doi:10.1530/eje.0.151U025
    • Morreale de Escobar G, Obregon MJ, Escobar Del Rey F. Role of thyroid hormone during early brain development. Eur J Endocrinol (2004) 151(Suppl 3):U25-37. doi:10.1530/eje.0.151U025.
    • (2004) Eur J Endocrinol , vol.151 , Issue.SUPPL. 3
    • Morreale de Escobar, G.1    Obregon, M.J.2    Escobar Del Rey, F.3
  • 2
    • 77957348924 scopus 로고    scopus 로고
    • The thyroid hormone receptor alpha1 protein is expressed in embryonic postmitotic neurons and persists in most adult neurons
    • doi:10.1210/me.2010-0175
    • Wallis K, Dudazy S, Van Hogerlinden M, Nordstrom K, Mittag J, Vennstrom B. The thyroid hormone receptor alpha1 protein is expressed in embryonic postmitotic neurons and persists in most adult neurons. Mol Endocrinol (2010) 24:1904-16. doi:10.1210/me.2010-0175.
    • (2010) Mol Endocrinol , vol.24 , pp. 1904-1916
    • Wallis, K.1    Dudazy, S.2    Van Hogerlinden, M.3    Nordstrom, K.4    Mittag, J.5    Vennstrom, B.6
  • 3
    • 25144470176 scopus 로고    scopus 로고
    • The roles of the iodothyronine deiodinases in mammalian development
    • doi:10.1089/thy.2005.15.823
    • Galton VA. The roles of the iodothyronine deiodinases in mammalian development. Thyroid (2005) 15:823-34. doi:10.1089/thy.2005.15.823.
    • (2005) Thyroid , vol.15 , pp. 823-834
    • Galton, V.A.1
  • 4
    • 70349327834 scopus 로고    scopus 로고
    • Thyroid function: thyroid hormones, iodine and the brain-an important concern
    • doi:10.1038/nrendo.2009.155
    • Laurberg P. Thyroid function: thyroid hormones, iodine and the brain-an important concern. Nat Rev Endocrinol (2009) 5:475-6. doi:10.1038/nrendo.2009.155.
    • (2009) Nat Rev Endocrinol , vol.5 , pp. 475-476
    • Laurberg, P.1
  • 5
    • 84877584150 scopus 로고    scopus 로고
    • Role of the type 2 iodothyronine deiodinase (D2) in the control of thyroid hormone signaling
    • doi:10.1016/j.bbagen.2012.08.019
    • Arrojo EDR, Fonseca TL, Werneck-De-Castro JP, Bianco AC. Role of the type 2 iodothyronine deiodinase (D2) in the control of thyroid hormone signaling. Biochim Biophys Acta (2013) 1830:3956-64. doi:10.1016/j.bbagen.2012.08.019.
    • (2013) Biochim Biophys Acta , vol.1830 , pp. 3956-3964
    • Arrojo, E.D.R.1    Fonseca, T.L.2    Werneck-De-Castro, J.P.3    Bianco, A.C.4
  • 6
    • 0021970929 scopus 로고
    • Neurological signs in congenital iodine-deficiency disorder (endemic cretinism)
    • doi:10.1111/j.1469-8749.1985.tb04542.x
    • DeLong GR, Stanbury JB, Fierro-Benitez R. Neurological signs in congenital iodine-deficiency disorder (endemic cretinism). Dev Med Child Neurol (1985) 27:317-24. doi:10.1111/j.1469-8749.1985.tb04542.x.
    • (1985) Dev Med Child Neurol , vol.27 , pp. 317-324
    • DeLong, G.R.1    Stanbury, J.B.2    Fierro-Benitez, R.3
  • 7
    • 0033802989 scopus 로고    scopus 로고
    • Thyroid hormone action in neural development
    • doi:10.1093/cercor/10.10.939
    • Thompson CC, Potter GB. Thyroid hormone action in neural development. Cereb Cortex (2000) 10:939-45. doi:10.1093/cercor/10.10.939.
    • (2000) Cereb Cortex , vol.10 , pp. 939-945
    • Thompson, C.C.1    Potter, G.B.2
  • 8
    • 7244223535 scopus 로고    scopus 로고
    • Thyroid hormone signaling is highly heterogeneous during pre-and postnatal brain development
    • doi:10.1677/jme.1.01570
    • Quignodon L, Legrand C, Allioli N, Guadano-Ferraz A, Bernal J, Samarut J, et al. Thyroid hormone signaling is highly heterogeneous during pre-and postnatal brain development. J Mol Endocrinol (2004) 33:467-76. doi:10.1677/jme.1.01570.
    • (2004) J Mol Endocrinol , vol.33 , pp. 467-476
    • Quignodon, L.1    Legrand, C.2    Allioli, N.3    Guadano-Ferraz, A.4    Bernal, J.5    Samarut, J.6
  • 9
    • 39749177046 scopus 로고    scopus 로고
    • Activation and inactivation of thyroid hormone by deiodinases: local action with general consequences
    • doi:10.1007/s00018-007-7396-0
    • Gereben B, Zeold A, Dentice M, Salvatore D, Bianco AC. Activation and inactivation of thyroid hormone by deiodinases: local action with general consequences. Cell Mol Life Sci (2008) 65:570-90. doi:10.1007/s00018-007-7396-0.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 570-590
    • Gereben, B.1    Zeold, A.2    Dentice, M.3    Salvatore, D.4    Bianco, A.C.5
  • 10
    • 67649842307 scopus 로고    scopus 로고
    • Minireview: defining the roles of the iodothyronine deiodinases: current concepts and challenges
    • doi:10.1210/en.2008-1588
    • St Germain DL, Galton VA, Hernandez A. Minireview: defining the roles of the iodothyronine deiodinases: current concepts and challenges. Endocrinology (2009) 150:1097-107. doi:10.1210/en.2008-1588.
    • (2009) Endocrinology , vol.150 , pp. 1097-1107
    • St Germain, D.L.1    Galton, V.A.2    Hernandez, A.3
  • 11
    • 0034964207 scopus 로고    scopus 로고
    • Thorough physiological review-physiological and molecular basis of thyroid hormone action
    • Yen PM. Thorough physiological review-physiological and molecular basis of thyroid hormone action. Physiol Rev (2001) 81:1097-142.
    • (2001) Physiol Rev , vol.81 , pp. 1097-1142
    • Yen, P.M.1
  • 13
    • 1842555649 scopus 로고    scopus 로고
    • Thyroid physiology and diagnostic evaluation of patients with thyroid disorders
    • Larsen PR, Kronenberg HM, Melmed S, Polonsky KS, editors. Philadelphia: Saunders
    • Larsen PR, Davies TF, Schlumberger M-J, Hay ID. Thyroid physiology and diagnostic evaluation of patients with thyroid disorders. In: Larsen PR, Kronenberg HM, Melmed S, Polonsky KS, editors. Williams Textbook of Endocrinology. Philadelphia: Saunders (2003). p. 331-73.
    • (2003) Williams Textbook of Endocrinology , pp. 331-373
    • Larsen, P.R.1    Davies, T.F.2    Schlumberger, M.-J.3    Hay, I.D.4
  • 14
    • 0024605316 scopus 로고
    • The role of 3,5,3'-triiodothyronine in the physiological action of thyroxine in the premetamorphic tadpole
    • doi:10.1210/endo-124-5-2427
    • Galton VA. The role of 3,5,3'-triiodothyronine in the physiological action of thyroxine in the premetamorphic tadpole. Endocrinology (1989) 124:2427-33. doi:10.1210/endo-124-5-2427.
    • (1989) Endocrinology , vol.124 , pp. 2427-2433
    • Galton, V.A.1
  • 15
    • 36849044236 scopus 로고    scopus 로고
    • The impact of iodised salt or iodine supplements on iodine status during pregnancy, lactation and infancy
    • doi:10.1017/S1368980007360965
    • Zimmermann MB. The impact of iodised salt or iodine supplements on iodine status during pregnancy, lactation and infancy. Public Health Nutr (2007) 10:1584-95. doi:10.1017/S1368980007360965.
    • (2007) Public Health Nutr , vol.10 , pp. 1584-1595
    • Zimmermann, M.B.1
  • 16
    • 55449135208 scopus 로고    scopus 로고
    • The changing role of maternal thyroid hormone in fetal brain development
    • doi:10.1053/j.semperi.2008.09.002
    • de Escobar GM, Ares S, Berbel P, Obregon MJ, Del Rey FE. The changing role of maternal thyroid hormone in fetal brain development. Semin Perinatol (2008) 32:380-6. doi:10.1053/j.semperi.2008.09.002.
    • (2008) Semin Perinatol , vol.32 , pp. 380-386
    • de Escobar, G.M.1    Ares, S.2    Berbel, P.3    Obregon, M.J.4    Del Rey, F.E.5
  • 17
    • 80053181984 scopus 로고    scopus 로고
    • Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum
    • doi:10.1089/thy.2011.0087
    • Stagnaro-Green A, Abalovich M, Alexander E, Azizi F, Mestman J, Negro R, et al. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum. Thyroid (2011) 21:1081-125. doi:10.1089/thy.2011.0087.
    • (2011) Thyroid , vol.21 , pp. 1081-1125
    • Stagnaro-Green, A.1    Abalovich, M.2    Alexander, E.3    Azizi, F.4    Mestman, J.5    Negro, R.6
  • 18
    • 0020051327 scopus 로고
    • An analysis of the sources and quantity of 3,5,3'-triiodothyronine specifically bound to nuclear receptors in rat cerebral cortex and cerebellum
    • doi:10.1210/endo-110-2-367
    • Crantz FR, Silva JE, Larsen PR. An analysis of the sources and quantity of 3,5,3'-triiodothyronine specifically bound to nuclear receptors in rat cerebral cortex and cerebellum. Endocrinology (1982) 110:367-75. doi:10.1210/endo-110-2-367.
    • (1982) Endocrinology , vol.110 , pp. 367-375
    • Crantz, F.R.1    Silva, J.E.2    Larsen, P.R.3
  • 19
    • 34250013578 scopus 로고    scopus 로고
    • The importance of thyroid hormone transporters for brain development and function
    • doi:10.1016/j.beem.2007.03.003
    • Heuer H. The importance of thyroid hormone transporters for brain development and function. Best Pract Res Clin Endocrinol Metab (2007) 21:265-76. doi:10.1016/j.beem.2007.03.003.
    • (2007) Best Pract Res Clin Endocrinol Metab , vol.21 , pp. 265-276
    • Heuer, H.1
  • 20
    • 72249119235 scopus 로고    scopus 로고
    • Translational implications of nongenomic actions of thyroid hormone initiated at its integrin receptor
    • doi:10.1152/ajpendo.00480.2009
    • Davis PJ, Davis FB, Lin HY, Mousa SA, Zhou M, Luidens MK. Translational implications of nongenomic actions of thyroid hormone initiated at its integrin receptor. Am J Physiol Endocrinol Metab (2009) 297:E1238-46. doi:10.1152/ajpendo.00480.2009.
    • (2009) Am J Physiol Endocrinol Metab , vol.297
    • Davis, P.J.1    Davis, F.B.2    Lin, H.Y.3    Mousa, S.A.4    Zhou, M.5    Luidens, M.K.6
  • 21
    • 0036936394 scopus 로고    scopus 로고
    • Insight into the physiological actions of thyroid hormone receptors from genetically modified mice
    • doi:10.1677/joe.0.1750553
    • O'Shea PJ, Williams GR. Insight into the physiological actions of thyroid hormone receptors from genetically modified mice. J Endocrinol (2002) 175:553-70. doi:10.1677/joe.0.1750553.
    • (2002) J Endocrinol , vol.175 , pp. 553-570
    • O'Shea, P.J.1    Williams, G.R.2
  • 23
    • 0141891099 scopus 로고    scopus 로고
    • Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter
    • doi:10.1074/jbc. M300909200
    • Friesema EC, Ganguly S, Abdalla A, Manning Fox JE, Halestrap AP, Visser TJ. Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter. J Biol Chem (2003) 278:40128-35. doi:10.1074/jbc. M300909200.
    • (2003) J Biol Chem , vol.278 , pp. 40128-40135
    • Friesema, E.C.1    Ganguly, S.2    Abdalla, A.3    Manning Fox, J.E.4    Halestrap, A.P.5    Visser, T.J.6
  • 24
    • 44649089035 scopus 로고    scopus 로고
    • Effective cellular uptake and efflux of thyroid hormone by human monocarboxylate transporter 10
    • doi:10.1210/me.2007-0112
    • Friesema EC, Jansen J, Jachtenberg JW, Visser WE, Kester MH, Visser TJ. Effective cellular uptake and efflux of thyroid hormone by human monocarboxylate transporter 10. Mol Endocrinol (2008) 22:1357-69. doi:10.1210/me.2007-0112.
    • (2008) Mol Endocrinol , vol.22 , pp. 1357-1369
    • Friesema, E.C.1    Jansen, J.2    Jachtenberg, J.W.3    Visser, W.E.4    Kester, M.H.5    Visser, T.J.6
  • 25
    • 33749431724 scopus 로고    scopus 로고
    • Deiodinases: implications of the local control of thyroid hormone action
    • doi:10.1172/JCI29812
    • Bianco AC, Kim BW. Deiodinases: implications of the local control of thyroid hormone action. J Clin Invest (2006) 116:2571-9. doi:10.1172/JCI29812.
    • (2006) J Clin Invest , vol.116 , pp. 2571-2579
    • Bianco, A.C.1    Kim, B.W.2
  • 26
    • 57649196306 scopus 로고    scopus 로고
    • The role of the placenta in thyroid hormone delivery to the fetus
    • doi:10.1038/ncpendmet1026
    • Chan SY, Vasilopoulou E, Kilby MD. The role of the placenta in thyroid hormone delivery to the fetus. Nat Clin Pract Endocrinol Metab (2009) 5:45-54. doi:10.1038/ncpendmet1026.
    • (2009) Nat Clin Pract Endocrinol Metab , vol.5 , pp. 45-54
    • Chan, S.Y.1    Vasilopoulou, E.2    Kilby, M.D.3
  • 27
    • 66649091781 scopus 로고    scopus 로고
    • Life without thyroxine to 3,5,3'-triiodothyronine conversion: studies in mice devoid of the 5'-deiodinases
    • doi:10.1210/en.2008-1572
    • Galton VA, Schneider MJ, Clark AS, St Germain DL. Life without thyroxine to 3,5,3'-triiodothyronine conversion: studies in mice devoid of the 5'-deiodinases. Endocrinology (2009) 150:2957-63. doi:10.1210/en.2008-1572.
    • (2009) Endocrinology , vol.150 , pp. 2957-2963
    • Galton, V.A.1    Schneider, M.J.2    Clark, A.S.3    St Germain, D.L.4
  • 28
    • 0018623195 scopus 로고
    • Cellular organization of the lateral and postinfundibular regions of the median eminence in the rat
    • doi:10.1007/BF00236998
    • Rodriguez EM, Gonzalez CB, Delannoy L. Cellular organization of the lateral and postinfundibular regions of the median eminence in the rat. Cell Tissue Res (1979) 201:377-408. doi:10.1007/BF00236998.
    • (1979) Cell Tissue Res , vol.201 , pp. 377-408
    • Rodriguez, E.M.1    Gonzalez, C.B.2    Delannoy, L.3
  • 29
    • 0030786397 scopus 로고    scopus 로고
    • Regional distribution of type 2 thyroxine deiodinase messenger ribonucleic acid in rat hypothalamus and pituitary and its regulation by thyroid hormone
    • doi:10.1210/endo.138.8.5318
    • Tu HM, Kim SW, Salvatore D, Bartha T, Legradi G, Larsen PR, et al. Regional distribution of type 2 thyroxine deiodinase messenger ribonucleic acid in rat hypothalamus and pituitary and its regulation by thyroid hormone. Endocrinology (1997) 138:3359-68. doi:10.1210/endo.138.8.5318.
    • (1997) Endocrinology , vol.138 , pp. 3359-3368
    • Tu, H.M.1    Kim, S.W.2    Salvatore, D.3    Bartha, T.4    Legradi, G.5    Larsen, P.R.6
  • 30
    • 0040379079 scopus 로고    scopus 로고
    • Expression of type 2 iodothyronine deiodinase in hypothyroid rat brain indicates an important role of thyroid hormone in the development of specific primary sensory systems
    • Guadano-Ferraz A, Escamez MJ, Rausell E, Bernal J. Expression of type 2 iodothyronine deiodinase in hypothyroid rat brain indicates an important role of thyroid hormone in the development of specific primary sensory systems. J Neurosci (1999) 19:3430-9.
    • (1999) J Neurosci , vol.19 , pp. 3430-3439
    • Guadano-Ferraz, A.1    Escamez, M.J.2    Rausell, E.3    Bernal, J.4
  • 31
    • 0025011704 scopus 로고
    • Congenital hypothyroidism, as studied in rat. Crucial role of maternal thyroxine but not of 3,5,3'-triiodothyronine in the protection of the fetal brain.
    • doi:10.1172/JCI114790
    • Calvo R, Obregon MJ, Ruiz De Ona C, Escobar Del Rey F, Morreale de Escobar G. Congenital hypothyroidism, as studied in rats. Crucial role of maternal thyroxine but not of 3,5,3'-triiodothyronine in the protection of the fetal brain. J Clin Invest (1990) 86:889-99. doi:10.1172/JCI114790.
    • (1990) J Clin Invest , vol.86 , pp. 889-899
    • Calvo, R.1    Obregon, M.J.2    Ruiz De Ona, C.3    Escobar Del Rey, F.4    Morreale de Escobar, G.5
  • 32
    • 0025885336 scopus 로고
    • Transport of iodothyronines from bloodstream to brain: contributions by blood:brain and choroid plexus:cerebrospinal fluid barriers
    • doi:10.1016/0006-8993(91)90194-Z
    • Dratman MB, Crutchfield FL, SchoenhoffMB. Transport of iodothyronines from bloodstream to brain: contributions by blood:brain and choroid plexus:cerebrospinal fluid barriers. Brain Res (1991) 554:229-36. doi:10.1016/0006-8993(91)90194-Z.
    • (1991) Brain Res , vol.554 , pp. 229-236
    • Dratman, M.B.1    Crutchfield, F.L.2    Schoenhoff, M.B.3
  • 33
    • 84860385945 scopus 로고    scopus 로고
    • Thyroid hormone action in cerebellum and cerebral cortex development
    • doi:10.4061/2011/145762
    • Chatonnet F, Picou F, Fauquier T, Flamant F. Thyroid hormone action in cerebellum and cerebral cortex development. J Thyroid Res (2011) 2011:145762. doi:10.4061/2011/145762.
    • (2011) J Thyroid Res , vol.2011 , pp. 145762
    • Chatonnet, F.1    Picou, F.2    Fauquier, T.3    Flamant, F.4
  • 34
    • 77954394706 scopus 로고    scopus 로고
    • The perivascular astroglial sheath provides a complete covering of the brain microvessels: an electron microscopic 3D reconstruction
    • doi:10.1002/glia.20990
    • Mathiisen TM, Lehre KP, Danbolt NC, Ottersen OP. The perivascular astroglial sheath provides a complete covering of the brain microvessels: an electron microscopic 3D reconstruction. Glia (2010) 58:1094-103. doi:10.1002/glia.20990.
    • (2010) Glia , vol.58 , pp. 1094-1103
    • Mathiisen, T.M.1    Lehre, K.P.2    Danbolt, N.C.3    Ottersen, O.P.4
  • 35
    • 0025936209 scopus 로고
    • Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor
    • Lazar MA, Berrodin TJ, Harding HP. Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor. Mol Cell Biol (1991) 11:5005-15.
    • (1991) Mol Cell Biol , vol.11 , pp. 5005-5015
    • Lazar, M.A.1    Berrodin, T.J.2    Harding, H.P.3
  • 36
    • 0025860708 scopus 로고
    • The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors
    • doi:10.1016/0092-8674(91)90021-P
    • Naar AM, Boutin JM, Lipkin SM, Yu VC, Holloway JM, Glass CK, et al. The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors. Cell (1991) 65:1267-79. doi:10.1016/0092-8674(91)90021-P.
    • (1991) Cell , vol.65 , pp. 1267-1279
    • Naar, A.M.1    Boutin, J.M.2    Lipkin, S.M.3    Yu, V.C.4    Holloway, J.M.5    Glass, C.K.6
  • 37
    • 0026557820 scopus 로고
    • Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers, homodimers, or heterodimers
    • doi:10.1210/mend.6.3.1316541
    • Forman BM, Casanova J, Raaka BM, Ghysdael J, Samuels HH. Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers, homodimers, or heterodimers. Mol Endocrinol (1992) 6:429-42. doi:10.1210/mend.6.3.1316541.
    • (1992) Mol Endocrinol , vol.6 , pp. 429-442
    • Forman, B.M.1    Casanova, J.2    Raaka, B.M.3    Ghysdael, J.4    Samuels, H.H.5
  • 38
    • 0026766654 scopus 로고
    • Binding characteristics of the thyroid hormone receptor homo-and heterodimers to consensus AGGTCA repeat motifs
    • doi:10.1210/me.6.7.1013
    • Wahlstrom GM, Sjoberg M, Andersson M, Nordstrom K, Vennstrom B. Binding characteristics of the thyroid hormone receptor homo-and heterodimers to consensus AGGTCA repeat motifs. Mol Endocrinol (1992) 6:1013-22. doi:10.1210/me.6.7.1013.
    • (1992) Mol Endocrinol , vol.6 , pp. 1013-1022
    • Wahlstrom, G.M.1    Sjoberg, M.2    Andersson, M.3    Nordstrom, K.4    Vennstrom, B.5
  • 39
    • 0027202156 scopus 로고
    • Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers
    • doi:10.1101/gad.7.7b.1423
    • Kurokawa R, Yu VC, Naar A, Kyakumoto S, Han Z, Silverman S, et al. Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers. Genes Dev (1993) 7:1423-35. doi:10.1101/gad.7.7b.1423.
    • (1993) Genes Dev , vol.7 , pp. 1423-1435
    • Kurokawa, R.1    Yu, V.C.2    Naar, A.3    Kyakumoto, S.4    Han, Z.5    Silverman, S.6
  • 40
    • 67749140014 scopus 로고    scopus 로고
    • The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors
    • doi:10.1074/jbc. M109.007542
    • Privalsky ML, Lee S, Hahm JB, Young BM, Fong RN, Chan IH. The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors. J Biol Chem (2009) 284:19554-63. doi:10.1074/jbc. M109.007542.
    • (2009) J Biol Chem , vol.284 , pp. 19554-19563
    • Privalsky, M.L.1    Lee, S.2    Hahm, J.B.3    Young, B.M.4    Fong, R.N.5    Chan, I.H.6
  • 41
    • 77953639982 scopus 로고    scopus 로고
    • Molecular aspects of thyroid hormone actions
    • doi:10.1210/er.2009-0007
    • Cheng SY, Leonard JL, Davis PJ. Molecular aspects of thyroid hormone actions. Endocr Rev (2010) 31:139-70. doi:10.1210/er.2009-0007.
    • (2010) Endocr Rev , vol.31 , pp. 139-170
    • Cheng, S.Y.1    Leonard, J.L.2    Davis, P.J.3
  • 42
    • 67749122138 scopus 로고    scopus 로고
    • Thyroid hormone receptor mutations found in renal clear cell carcinomas alter corepressor release and reveal helix 12 as key determinant of corepressor specificity
    • doi:10.1210/me.2009-0126
    • Rosen MD, Privalsky ML. Thyroid hormone receptor mutations found in renal clear cell carcinomas alter corepressor release and reveal helix 12 as key determinant of corepressor specificity. Mol Endocrinol (2009) 23:1183-92. doi:10.1210/me.2009-0126.
    • (2009) Mol Endocrinol , vol.23 , pp. 1183-1192
    • Rosen, M.D.1    Privalsky, M.L.2
  • 43
    • 70350433461 scopus 로고    scopus 로고
    • Isoform-specific transcriptional activity of overlapping target genes that respond to thyroid hormone receptors alpha1 and beta1
    • doi:10.1210/me.2009-0025
    • Chan IH, Privalsky ML. Isoform-specific transcriptional activity of overlapping target genes that respond to thyroid hormone receptors alpha1 and beta1. Mol Endocrinol (2009) 23:1758-75. doi:10.1210/me.2009-0025.
    • (2009) Mol Endocrinol , vol.23 , pp. 1758-1775
    • Chan, I.H.1    Privalsky, M.L.2
  • 44
    • 84874247902 scopus 로고    scopus 로고
    • Genome-wide analysis of thyroid hormone receptors shared and specific functions in neural cells
    • doi:10.1073/pnas.1210626110
    • Chatonnet F, Guyot R, Benoit G, Flamant F. Genome-wide analysis of thyroid hormone receptors shared and specific functions in neural cells. Proc Natl Acad Sci U S A (2013) 110:E766-75. doi:10.1073/pnas.1210626110.
    • (2013) Proc Natl Acad Sci U S A , vol.110
    • Chatonnet, F.1    Guyot, R.2    Benoit, G.3    Flamant, F.4
  • 45
    • 0032174666 scopus 로고    scopus 로고
    • Multiple isoforms of thyroid hormone receptor: an analysis of their relative contribution in mediating thyroid hormone action
    • Murata Y. Multiple isoforms of thyroid hormone receptor: an analysis of their relative contribution in mediating thyroid hormone action. Nagoya J Med Sci (1998) 61:103-15.
    • (1998) Nagoya J Med Sci , vol.61 , pp. 103-115
    • Murata, Y.1
  • 46
    • 0033950142 scopus 로고    scopus 로고
    • Functions of thyroid hormone receptors in mice
    • doi:10.1089/thy.2000.10.41
    • Forrest D, Vennstrom B. Functions of thyroid hormone receptors in mice. Thyroid (2000) 10:41-52. doi:10.1089/thy.2000.10.41.
    • (2000) Thyroid , vol.10 , pp. 41-52
    • Forrest, D.1    Vennstrom, B.2
  • 47
    • 0033859843 scopus 로고    scopus 로고
    • The mechanism of action of thyroid hormones
    • doi:10.1146/annurev.physiol.62.1.439
    • Zhang J, Lazar MA. The mechanism of action of thyroid hormones. Annu Rev Physiol (2000) 62:439-66. doi:10.1146/annurev.physiol.62.1.439.
    • (2000) Annu Rev Physiol , vol.62 , pp. 439-466
    • Zhang, J.1    Lazar, M.A.2
  • 48
    • 0037828418 scopus 로고    scopus 로고
    • Thyroid hormone action: insight from transgenic mouse models
    • doi:10.2310/6650.2003.39191
    • Wondisford FE. Thyroid hormone action: insight from transgenic mouse models. J Investig Med (2003) 51:215-20. doi:10.2310/6650.2003.39191.
    • (2003) J Investig Med , vol.51 , pp. 215-220
    • Wondisford, F.E.1
  • 49
    • 18244381247 scopus 로고    scopus 로고
    • Isoform-dependent actions of thyroid hormone nuclear receptors: lessons from knockin mutant mice
    • doi:10.1016/j.steroids.2005.02.003
    • Cheng SY. Isoform-dependent actions of thyroid hormone nuclear receptors: lessons from knockin mutant mice. Steroids (2005) 70:450-4. doi:10.1016/j.steroids.2005.02.003.
    • (2005) Steroids , vol.70 , pp. 450-454
    • Cheng, S.Y.1
  • 50
    • 0038407750 scopus 로고    scopus 로고
    • Thyroid hormone receptors: lessons from knockout and knock-in mutant mice
    • doi:10.1016/S1043-2760(02)00043-7
    • Flamant F, Samarut J. Thyroid hormone receptors: lessons from knockout and knock-in mutant mice. Trends Endocrinol Metab (2003) 14:85-90. doi:10.1016/S1043-2760(02)00043-7.
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 85-90
    • Flamant, F.1    Samarut, J.2
  • 51
    • 0026651722 scopus 로고
    • Quantitation of rat tissue thyroid hormone binding receptor isoforms by immunoprecipitation of nuclear triiodothyronine binding capacity
    • Schwartz HL, Strait KA, Ling NC, Oppenheimer JH. Quantitation of rat tissue thyroid hormone binding receptor isoforms by immunoprecipitation of nuclear triiodothyronine binding capacity. J Biol Chem (1992) 267:11794-9.
    • (1992) J Biol Chem , vol.267 , pp. 11794-11799
    • Schwartz, H.L.1    Strait, K.A.2    Ling, N.C.3    Oppenheimer, J.H.4
  • 52
    • 0344442669 scopus 로고    scopus 로고
    • Thyroid hormone induces cerebellar Purkinje cell dendritic development via the thyroid hormone receptor alpha1
    • Heuer H, Mason CA. Thyroid hormone induces cerebellar Purkinje cell dendritic development via the thyroid hormone receptor alpha1. J Neurosci (2003) 23:10604-12.
    • (2003) J Neurosci , vol.23 , pp. 10604-10612
    • Heuer, H.1    Mason, C.A.2
  • 53
    • 0035211984 scopus 로고    scopus 로고
    • Targeted disruption of the type 2 selenodeiodinase gene (DIO2) results in a phenotype of pituitary resistance to T4
    • doi:10.1210/me.15.12.2137
    • Schneider MJ, Fiering SN, Pallud SE, Parlow AF, St Germain DL, Galton VA. Targeted disruption of the type 2 selenodeiodinase gene (DIO2) results in a phenotype of pituitary resistance to T4. Mol Endocrinol (2001) 15:2137-48. doi:10.1210/me.15.12.2137.
    • (2001) Mol Endocrinol , vol.15 , pp. 2137-2148
    • Schneider, M.J.1    Fiering, S.N.2    Pallud, S.E.3    Parlow, A.F.4    St Germain, D.L.5    Galton, V.A.6
  • 54
    • 79951883954 scopus 로고    scopus 로고
    • Distinct roles of deiodinases on the phenotype of MCT8 defect: a comparison of eight different mouse genotypes
    • doi:10.1210/en.2010-0900
    • Liao XH, Di Cosmo C, Dumitrescu AM, Hernandez A, Van Sande J, St Germain DL, et al. Distinct roles of deiodinases on the phenotype of MCT8 defect: a comparison of eight different mouse genotypes. Endocrinology (2011) 152:1180-91. doi:10.1210/en.2010-0900.
    • (2011) Endocrinology , vol.152 , pp. 1180-1191
    • Liao, X.H.1    Di Cosmo, C.2    Dumitrescu, A.M.3    Hernandez, A.4    Van Sande, J.5    St Germain, D.L.6
  • 55
    • 77953158522 scopus 로고    scopus 로고
    • Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8-and deiodinase-2-deficient mice
    • doi:10.1210/en.2009-0944
    • Morte B, Ceballos A, Diez D, Grijota-Martinez C, Dumitrescu AM, Di Cosmo C, et al. Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8-and deiodinase-2-deficient mice. Endocrinology (2010) 151:2381-7. doi:10.1210/en.2009-0944.
    • (2010) Endocrinology , vol.151 , pp. 2381-2387
    • Morte, B.1    Ceballos, A.2    Diez, D.3    Grijota-Martinez, C.4    Dumitrescu, A.M.5    Di Cosmo, C.6
  • 56
    • 57349180438 scopus 로고    scopus 로고
    • Expression of the thyroid hormone transporters monocarboxylate transporter-8 (SLC16A2) and organic ion transporter-14 (SLCO1C1) at the blood-brain barrier
    • doi:10.1210/en.2008-0378
    • Roberts LM, Woodford K, Zhou M, Black DS, Haggerty JE, Tate EH, et al. Expression of the thyroid hormone transporters monocarboxylate transporter-8 (SLC16A2) and organic ion transporter-14 (SLCO1C1) at the blood-brain barrier. Endocrinology (2008) 149:6251-61. doi:10.1210/en.2008-0378.
    • (2008) Endocrinology , vol.149 , pp. 6251-6261
    • Roberts, L.M.1    Woodford, K.2    Zhou, M.3    Black, D.S.4    Haggerty, J.E.5    Tate, E.H.6
  • 57
    • 66449128624 scopus 로고    scopus 로고
    • Importance of monocarboxylate transporter 8 for the blood-brain barrier-dependent availability of 3,5,3'-triiodo-l-thyronine
    • doi:10.1210/en.2008-1616
    • Ceballos A, Belinchon MM, Sanchez-Mendoza E, Grijota-Martinez C, Dumitrescu AM, RefetoffS, et al. Importance of monocarboxylate transporter 8 for the blood-brain barrier-dependent availability of 3,5,3'-triiodo-l-thyronine. Endocrinology (2009) 150:2491-6. doi:10.1210/en.2008-1616.
    • (2009) Endocrinology , vol.150 , pp. 2491-2496
    • Ceballos, A.1    Belinchon, M.M.2    Sanchez-Mendoza, E.3    Grijota-Martinez, C.4    Dumitrescu, A.M.5    Refetoff, S.6
  • 58
    • 84861313021 scopus 로고    scopus 로고
    • Critical role of types 2 and 3 deiodinases in the negative regulation of gene expression by T(3)in the mouse cerebral cortex
    • doi:10.1210/en.2011-1905
    • Hernandez A, Morte B, Belinchon MM, Ceballos A, Bernal J. Critical role of types 2 and 3 deiodinases in the negative regulation of gene expression by T(3)in the mouse cerebral cortex. Endocrinology (2012) 153:2919-28. doi:10.1210/en.2011-1905.
    • (2012) Endocrinology , vol.153 , pp. 2919-2928
    • Hernandez, A.1    Morte, B.2    Belinchon, M.M.3    Ceballos, A.4    Bernal, J.5
  • 59
    • 84879310018 scopus 로고    scopus 로고
    • Changes in thyroid status during perinatal development of MCT8-deficient male mice
    • doi:10.1210/en.2012-2031
    • Ferrara AM, Liao XH, Gil-Ibanez P, Marcinkowski T, Bernal J, Weiss RE, et al. Changes in thyroid status during perinatal development of MCT8-deficient male mice. Endocrinology (2013) 154:2533-41. doi:10.1210/en.2012-2031.
    • (2013) Endocrinology , vol.154 , pp. 2533-2541
    • Ferrara, A.M.1    Liao, X.H.2    Gil-Ibanez, P.3    Marcinkowski, T.4    Bernal, J.5    Weiss, R.E.6
  • 60
    • 0037081866 scopus 로고    scopus 로고
    • Thyroid hormone exerts site-specific effects on SRC-1 and NCoR expression selectively in the neonatal rat brain
    • doi:10.1016/S0303-7207(01)00672-4
    • Iannacone EA, Yan AW, Gauger KJ, Dowling AL, Zoeller RT. Thyroid hormone exerts site-specific effects on SRC-1 and NCoR expression selectively in the neonatal rat brain. Mol Cell Endocrinol (2002) 186:49-59. doi:10.1016/S0303-7207(01)00672-4.
    • (2002) Mol Cell Endocrinol , vol.186 , pp. 49-59
    • Iannacone, E.A.1    Yan, A.W.2    Gauger, K.J.3    Dowling, A.L.4    Zoeller, R.T.5
  • 61
    • 18744387971 scopus 로고    scopus 로고
    • Comparative distribution of the mammalian mediator subunit thyroid hormone receptor-associated protein (TRAP220) mRNA in developing and adult rodent brain
    • doi:10.1046/j.1460-9568.2002.02115.x
    • Galeeva A, Treuter E, Tuohimaa P, Pelto-Huikko M. Comparative distribution of the mammalian mediator subunit thyroid hormone receptor-associated protein (TRAP220) mRNA in developing and adult rodent brain. Eur J Neurosci (2002) 16:671-83. doi:10.1046/j.1460-9568.2002.02115.x.
    • (2002) Eur J Neurosci , vol.16 , pp. 671-683
    • Galeeva, A.1    Treuter, E.2    Tuohimaa, P.3    Pelto-Huikko, M.4


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