Development and optimization of gastroretentive mucoadhesive microspheres of gabapentin by Box-Behnken design

Artificial Cells, Nanomedicine and Biotechnology

Volumn 42, Issue 3, 2014, Pages 167-177

  Gaur, Praveen Kumar ^a   Mishra, Shikha ^b   Kumar, Avdhesh ^a   Panda, Bibhu Prasad ^b  

^a ITS Paramedical College (Pharmacy)   (India)

^b HAMDARD UNIVERSITY   (India)

Author keywords

Behnken design; Ionotropic gelation; Microspheres; Sodium alginate

Indexed keywords

EFFICIENCY; IONOTROPIC GELATION; MICROSPHERES; PARTICLE SIZE; SODIUM ALGINATE;

ABSORPTION WINDOWS; BOX-BEHNKEN DESIGN; CARRIER-MEDIATED; ENTRAPMENT EFFICIENCY; HIGUCHI MODEL; MUCOADHESION; SATURATION KINETICS; SODIUM CARBOXYMETHYLCELLULOSE;

DESIGN;

CALCIUM CHLORIDE; GABAPENTIN; MICROSPHERE; 4 AMINOBUTYRIC ACID; AMINE; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE;

ARTICLE; CONTROLLED DRUG RELEASE; DRUG ABSORPTION; DRUG DESIGN; DRUG FORMULATION; DRUG MECHANISM; IN VITRO STUDY; MUCOADHESION; PARTICLE SIZE; STOMACH ABSORPTION; ADHESION; ANIMAL; CHEMISTRY; DRUG RELEASE; MEDICINAL CHEMISTRY; METABOLISM; MOUSE; PROCEDURES; STOMACH MUCOSA;

ADHESIVENESS; AMINES; ANIMALS; CHEMISTRY, PHARMACEUTICAL; CYCLOHEXANECARBOXYLIC ACIDS; DRUG LIBERATION; GAMMA-AMINOBUTYRIC ACID; GASTRIC ABSORPTION; GASTRIC MUCOSA; MICE; MICROSPHERES; PARTICLE SIZE;

EID: 84901030090     PISSN: 21691401     EISSN: 2169141X     Source Type: Journal    
DOI: 10.3109/21691401.2013.800081     Document Type: Article

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