Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization

FASEB Journal

Volumn 28, Issue 4, 2014, Pages 1805-1818

  Van Audenhove, Isabel ^a   Boucherie, Ciska ^a   Pieters, Leen ^a   Zwaenepoel, Olivier ^a   Vanloo, Berlinda ^a   Martens, Evelien ^a   Verbrugge, Charlotte ^a   Hassanzadeh Ghassabeh, Gholamreza ^b   Vandekerckhove, Joël ^a   Cornelissen, Maria ^a   De Ganck, Ariane ^a   Gettemans, Jan ^a  

^a GHENT UNIVERSITY   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

Cytoskeletal protein modulation; Heavy chain only antibodies; Invasive protrusions; Oncotargets

Indexed keywords

CORTACTIN; F ACTIN; FASCIN; GELATINASE B; NANOBODY;

ACTIN FILAMENT; ARTICLE; BREAST CANCER CELL LINE; CELL INVASION; CELL MATURATION; CELL MEMBRANE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; ENZYME RELEASE; HEK293 CELL LINE; HUMAN; HUMAN CELL; INVADOPODIUM; PRIORITY JOURNAL; PROSTATE CANCER CELL LINE; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN FUNCTION;

CYTOSKELETAL PROTEIN MODULATION; HEAVY-CHAIN ONLY ANTIBODIES; INVASIVE PROTRUSIONS; ONCOTARGETS;

ACTINS; BLOTTING, WESTERN; CARRIER PROTEINS; CELL LINE, TUMOR; CELL MEMBRANE; CELL MOVEMENT; CELL SURFACE EXTENSIONS; CORTACTIN; CYTOSKELETAL PROTEINS; EPITOPES; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MATRIX METALLOPROTEINASE 9; MICROFILAMENT PROTEINS; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; NEOPLASMS; PROTEIN BINDING; PSEUDOPODIA; SINGLE-DOMAIN ANTIBODIES; SRC HOMOLOGY DOMAINS; THERMODYNAMICS;

EID: 84901022975     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-242537     Document Type: Article

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