메뉴 건너뛰기




Volumn 5, Issue APR, 2014, Pages

Endocannabinoids are involved in male vertebrate reproduction: Regulatory mechanisms at central and gonadal level

Author keywords

Chromatin remodeling; GnRH; Hypothalamus; Male fertility; Pituitary; Spermatogenesis

Indexed keywords

CANNABINOID 2 RECEPTOR; ENDOCANNABINOID; GONADORELIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1;

EID: 84901022923     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2014.00054     Document Type: Review
Times cited : (44)

References (108)
  • 1
    • 33645762068 scopus 로고    scopus 로고
    • The phylogenetic distribution and evolutionary origins of endocannabinoid signalling
    • doi:10.1007/3-540-26573-2_9
    • Elphick MR, Egertová M. The phylogenetic distribution and evolutionary origins of endocannabinoid signalling. Handb Exp Pharmacol (2005) 168:283-97. doi:10.1007/3-540-26573-2_9.
    • (2005) Handb Exp Pharmacol , vol.168 , pp. 283-297
    • Elphick, M.R.1    Egertová, M.2
  • 2
    • 84868147782 scopus 로고    scopus 로고
    • The evolution and comparative neurobiology of endocannabinoid signaling
    • doi:10.1098/rstb.2011.0394
    • Elphick MR. The evolution and comparative neurobiology of endocannabinoid signaling. Philos Trans R Soc B Biol Sci (2012) 367:3201-15. doi:10.1098/rstb.2011.0394.
    • (2012) Philos Trans R Soc B Biol Sci , vol.367 , pp. 3201-3215
    • Elphick, M.R.1
  • 3
    • 33645774927 scopus 로고    scopus 로고
    • Distribution of cannabinoid receptors in the central and peripheral nervous system
    • doi:10.1007/3-540-26573-2_10
    • Mackie K. Distribution of cannabinoid receptors in the central and peripheral nervous system. Handb Exp Pharmacol (2005) 168:299-325. doi:10.1007/3-540-26573-2_10.
    • (2005) Handb Exp Pharmacol , vol.168 , pp. 299-325
    • Mackie, K.1
  • 4
    • 0042422112 scopus 로고    scopus 로고
    • Xenopus laevis CB1 cannabinoid receptor: molecular cloning and mRNA distribution in the central nervous system
    • doi:10.1002/cne.10808
    • Cottone E, Salio C, Conrath M, Franzoni MF. Xenopus laevis CB1 cannabinoid receptor: molecular cloning and mRNA distribution in the central nervous system. J Comp Neurol (2003) 464:487-96. doi:10.1002/cne.10808.
    • (2003) J Comp Neurol , vol.464 , pp. 487-496
    • Cottone, E.1    Salio, C.2    Conrath, M.3    Franzoni, M.F.4
  • 5
    • 16344394735 scopus 로고    scopus 로고
    • Expression and distribution of CB1 cannabinoid receptors in the central nervous system of the African cichlid fish Pelvicachromis pulcher
    • doi:10.1002/cne.20502
    • Cottone E, Forno S, Campantico E, Guastalla A, Viltono L, Mackie K, et al. Expression and distribution of CB1 cannabinoid receptors in the central nervous system of the African cichlid fish Pelvicachromis pulcher. J Comp Neurol (2005) 485:293-303. doi:10.1002/cne.20502.
    • (2005) J Comp Neurol , vol.485 , pp. 293-303
    • Cottone, E.1    Forno, S.2    Campantico, E.3    Guastalla, A.4    Viltono, L.5    Mackie, K.6
  • 6
    • 26844504226 scopus 로고    scopus 로고
    • Identification and functional characterization of brainstem cannabinoid CB2 receptors
    • doi:10.1126/science.1115740
    • Van Sickle MD, Duncan M, Kingsley PJ, Mouihate A, Urbani P, Mackie K, et al. Identification and functional characterization of brainstem cannabinoid CB2 receptors. Science (2005) 310(5746):329-32. doi:10.1126/science.1115740.
    • (2005) Science , vol.310 , Issue.5746 , pp. 329-332
    • Van Sickle, M.D.1    Duncan, M.2    Kingsley, P.J.3    Mouihate, A.4    Urbani, P.5    Mackie, K.6
  • 7
    • 77952623444 scopus 로고    scopus 로고
    • CB2: a cannabinoid receptor with an identity crisis
    • doi:10.1111/j.1476-5381.2010.00729.x
    • Atwood BK, Mackie K. CB2: a cannabinoid receptor with an identity crisis. Br J Pharmacol (2010) 160:467-79. doi:10.1111/j.1476-5381.2010.00729.x.
    • (2010) Br J Pharmacol , vol.160 , pp. 467-479
    • Atwood, B.K.1    Mackie, K.2
  • 8
    • 84884290836 scopus 로고    scopus 로고
    • Cannabinoid receptors are widely expressed in goldfish: molecular cloning of a CB2-like receptor and evaluation of CB1 and CB2 mRNA expression profiles in different organs
    • doi:10.1007/s10695-013-9783-9
    • Cottone E, Pomatto V, Cerri F, Campantico E, Mackie K, Delpero M, et al. Cannabinoid receptors are widely expressed in goldfish: molecular cloning of a CB2-like receptor and evaluation of CB1 and CB2 mRNA expression profiles in different organs. Fish Physiol Biochem (2013) 39:1287-96. doi:10.1007/s10695-013-9783-9.
    • (2013) Fish Physiol Biochem , vol.39 , pp. 1287-1296
    • Cottone, E.1    Pomatto, V.2    Cerri, F.3    Campantico, E.4    Mackie, K.5    Delpero, M.6
  • 9
    • 77950660113 scopus 로고    scopus 로고
    • Endocannabinoids as regulators of transient receptor potential (TRP) channels: a further opportunity to develop new endocannabinoid-based therapeutic drugs
    • doi:10.2174/092986710790980078
    • Di Marzo V, De Petrocellis L. Endocannabinoids as regulators of transient receptor potential (TRP) channels: a further opportunity to develop new endocannabinoid-based therapeutic drugs. Curr Med Chem (2010) 17:1430-49. doi:10.2174/092986710790980078.
    • (2010) Curr Med Chem , vol.17 , pp. 1430-1449
    • Di Marzo, V.1    De Petrocellis, L.2
  • 10
    • 84867113185 scopus 로고    scopus 로고
    • Endocannabinoid signaling and synaptic function
    • doi:10.1016/j.neuron.2012.09.020
    • Castillo PE, Younts TJ, Chávez AE, Hashimotodani Y. Endocannabinoid signaling and synaptic function. Neuron (2012) 76(1):70-81. doi:10.1016/j.neuron.2012.09.020.
    • (2012) Neuron , vol.76 , Issue.1 , pp. 70-81
    • Castillo, P.E.1    Younts, T.J.2    Chávez, A.E.3    Hashimotodani, Y.4
  • 11
    • 44849141696 scopus 로고    scopus 로고
    • Enzymatic pathways that regulate endocannabinoid signaling in the nervous system
    • doi:10.1021/cr0782067
    • Ahn K, McKinney MK, Cravatt BF. Enzymatic pathways that regulate endocannabinoid signaling in the nervous system. Chem Rev (2008) 108:1687-707. doi:10.1021/cr0782067.
    • (2008) Chem Rev , vol.108 , pp. 1687-1707
    • Ahn, K.1    McKinney, M.K.2    Cravatt, B.F.3
  • 12
    • 67449119913 scopus 로고    scopus 로고
    • The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation
    • doi:10.1016/j.phrs.2009.02.010
    • Di Marzo V. The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation. Pharmacol Res (2009) 60:77-84. doi:10.1016/j.phrs.2009.02.010.
    • (2009) Pharmacol Res , vol.60 , pp. 77-84
    • Di Marzo, V.1
  • 13
    • 78650120798 scopus 로고    scopus 로고
    • International union of basic and clinical pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB1 and CB2.
    • doi:10.1124/pr.110.003004
    • Pertwee RG, Howlett AC, Abood ME, Alexander SP, Di Marzo V, Elphick MR, et al. International union of basic and clinical pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB1 and CB2. Pharmacol Rev (2010) 62:588-631. doi:10.1124/pr.110.003004.
    • (2010) Pharmacol Rev , vol.62 , pp. 588-631
    • Pertwee, R.G.1    Howlett, A.C.2    Abood, M.E.3    Alexander, S.P.4    Di Marzo, V.5    Elphick, M.R.6
  • 14
    • 0242268553 scopus 로고    scopus 로고
    • The molecular logic of endocannabinoid signalling
    • doi:10.1038/nrn1247
    • Piomelli D. The molecular logic of endocannabinoid signalling. Nat Rev Neurosci (2003) 4:873-84. doi:10.1038/nrn1247.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 873-884
    • Piomelli, D.1
  • 15
    • 84893834060 scopus 로고    scopus 로고
    • Updates in reproduction coming from the endocannabinoid system
    • doi:10.1155/2014/412354
    • Meccariello R, Battista N, Bradshaw HB, Wang H. Updates in reproduction coming from the endocannabinoid system. Int J Endocrinol (2014) 2014:412354. doi:10.1155/2014/412354.
    • (2014) Int J Endocrinol , vol.2014 , pp. 412354
    • Meccariello, R.1    Battista, N.2    Bradshaw, H.B.3    Wang, H.4
  • 16
    • 84885366373 scopus 로고    scopus 로고
    • Role of the endocannabinoid system in the central regulation of nonmammalian vertebrate reproduction
    • doi:10.1155/2013/941237
    • Cottone E, Pomatto V, Bovolin P. Role of the endocannabinoid system in the central regulation of nonmammalian vertebrate reproduction. Int J Endocrinol (2013) 2013:941237. doi:10.1155/2013/941237.
    • (2013) Int J Endocrinol , vol.2013 , pp. 941237
    • Cottone, E.1    Pomatto, V.2    Bovolin, P.3
  • 17
    • 84858745752 scopus 로고    scopus 로고
    • The role of endocannabinoids in gonadal function and fertility along the evolutionary axis
    • doi:10.1016/j.mce.2012.01.014
    • Battista N, Meccariello R, Cobellis G, Fasano S, Di Tommaso M, Piazzi V, et al. The role of endocannabinoids in gonadal function and fertility along the evolutionary axis. Mol Cell Endocrinol (2012) 355:1-14. doi:10.1016/j.mce.2012.01.014.
    • (2012) Mol Cell Endocrinol , vol.355 , pp. 1-14
    • Battista, N.1    Meccariello, R.2    Cobellis, G.3    Fasano, S.4    Di Tommaso, M.5    Piazzi, V.6
  • 18
    • 0025053247 scopus 로고
    • Effects of delta-9-tetrahydrocannabinol, cannabinol and cannabidiol, alone and in combinations, on luteinizing hormone and prolactin release and on hypothalamic neurotransmitters in the male rat
    • doi:10.1159/000125604
    • Murphy LL, Steger RW, Smith MS, Bartke A. Effects of delta-9-tetrahydrocannabinol, cannabinol and cannabidiol, alone and in combinations, on luteinizing hormone and prolactin release and on hypothalamic neurotransmitters in the male rat. Neuroendocrinology (1990) 52(4):316-21. doi:10.1159/000125604.
    • (1990) Neuroendocrinology , vol.52 , Issue.4 , pp. 316-321
    • Murphy, L.L.1    Steger, R.W.2    Smith, M.S.3    Bartke, A.4
  • 19
    • 0344938184 scopus 로고    scopus 로고
    • Function of cannabinoid receptors in the neuroendocrine regulation of hormone secretion
    • doi:10.1006/nbdi.1998.0224
    • Murphy LL, Muñoz RM, Adrian BA, Villanúa MA. Function of cannabinoid receptors in the neuroendocrine regulation of hormone secretion. Neurobiol Dis (1998) 5:432-46. doi:10.1006/nbdi.1998.0224.
    • (1998) Neurobiol Dis , vol.5 , pp. 432-446
    • Murphy, L.L.1    Muñoz, R.M.2    Adrian, B.A.3    Villanúa, M.A.4
  • 20
    • 4143070323 scopus 로고    scopus 로고
    • The inhibitory effect of anandamide on luteinizing hormone releasing hormone secretion is reversed by estrogen
    • doi:10.1073/pnas.0404366101
    • Scorticati C, Fernandez-Solari J, De Laurentiis A, Mohn C, Prestifilippo JP, Lasaga M, et al. The inhibitory effect of anandamide on luteinizing hormone releasing hormone secretion is reversed by estrogen. Proc Natl Acad Sci U S A (2004) 32:11891-6. doi:10.1073/pnas.0404366101.
    • (2004) Proc Natl Acad Sci U S A , vol.32 , pp. 11891-11896
    • Scorticati, C.1    Fernandez-Solari, J.2    De Laurentiis, A.3    Mohn, C.4    Prestifilippo, J.P.5    Lasaga, M.6
  • 21
    • 0034809865 scopus 로고    scopus 로고
    • The central cannabinoid receptor inactivation suppresses endocrine reproductive functions
    • doi:10.1006/bbrc.2001.4977
    • Wenger T, Ledent C, Csernus V, Gerendai I. The central cannabinoid receptor inactivation suppresses endocrine reproductive functions. Biochem Biophys Res Commun (2001) 284:363-8. doi:10.1006/bbrc.2001.4977.
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 363-368
    • Wenger, T.1    Ledent, C.2    Csernus, V.3    Gerendai, I.4
  • 22
    • 84881582187 scopus 로고    scopus 로고
    • Low 17beta-estradiol levels in Cnr1 knock-out mice affect spermatid chromatin remodeling by interfering with chromatin reorganization
    • doi:10.1095/biolreprod.112.105726
    • Cacciola G, Chioccarelli T, Altucci L, Ledent C, Mason JI, Fasano S, et al. Low 17beta-estradiol levels in Cnr1 knock-out mice affect spermatid chromatin remodeling by interfering with chromatin reorganization. Biol Reprod (2013) 88:152. doi:10.1095/biolreprod.112.105726.
    • (2013) Biol Reprod , vol.88 , pp. 152
    • Cacciola, G.1    Chioccarelli, T.2    Altucci, L.3    Ledent, C.4    Mason, J.I.5    Fasano, S.6
  • 23
    • 0031929438 scopus 로고    scopus 로고
    • Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system
    • doi:10.1016/S0306-4522(97)00436-3
    • Tsou K, Brown S, Sanudo-Pena MC, Mackie K, Walker JM. Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience (1998) 83:393-411. doi:10.1016/S0306-4522(97)00436-3.
    • (1998) Neuroscience , vol.83 , pp. 393-411
    • Tsou, K.1    Brown, S.2    Sanudo-Pena, M.C.3    Mackie, K.4    Walker, J.M.5
  • 24
    • 85047690626 scopus 로고    scopus 로고
    • The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
    • doi:10.1172/JCI200317725
    • Cota D, Marsicano G, Tschöp M, Grübler Y, Flachskamm C, Schubert M, et al. The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest (2003) 112(3):423-31. doi:10.1172/JCI200317725.
    • (2003) J Clin Invest , vol.112 , Issue.3 , pp. 423-431
    • Cota, D.1    Marsicano, G.2    Tschöp, M.3    Grübler, Y.4    Flachskamm, C.5    Schubert, M.6
  • 25
    • 0033452718 scopus 로고    scopus 로고
    • Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain
    • doi:10.1046/j.1460-9568.1999.00847.x
    • Marsicano G, Lutz B. Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain. Eur J Neurosci (1999) 11(12):4213-25. doi:10.1046/j.1460-9568.1999.00847.x.
    • (1999) Eur J Neurosci , vol.11 , Issue.12 , pp. 4213-4225
    • Marsicano, G.1    Lutz, B.2
  • 26
    • 0027492734 scopus 로고
    • Localization of cannabinoid receptor mRNA in rat brain
    • doi:10.1002/cne.903270406
    • Matsuda LA, Bonner TI, Lolait SJ. Localization of cannabinoid receptor mRNA in rat brain. J Comp Neurol (1993) 327:535-50. doi:10.1002/cne.903270406.
    • (1993) J Comp Neurol , vol.327 , pp. 535-550
    • Matsuda, L.A.1    Bonner, T.I.2    Lolait, S.J.3
  • 27
    • 34447635408 scopus 로고    scopus 로고
    • Distribution of type 1 cannabinoid receptor (CB1)-immunoreactive axons in the mouse hypothalamus
    • doi:10.1002/cne.21383
    • Wittmann G, Deli L, Kalló I, Hrabovszky E, Watanabe M, Liposits Z, et al. Distribution of type 1 cannabinoid receptor (CB1)-immunoreactive axons in the mouse hypothalamus. J Comp Neurol (2007) 503(2):270-9. doi:10.1002/cne.21383.
    • (2007) J Comp Neurol , vol.503 , Issue.2 , pp. 270-279
    • Wittmann, G.1    Deli, L.2    Kalló, I.3    Hrabovszky, E.4    Watanabe, M.5    Liposits, Z.6
  • 28
    • 42449097695 scopus 로고    scopus 로고
    • Interplay between the endocannabinoid system and GnRH-I in the forebrain of the anuran amphibian Rana esculenta
    • doi:10.1210/en.2007-1357
    • Meccariello R, Franzoni MF, Chianese R, Cottone E, Scarpa D, Donna D, et al. Interplay between the endocannabinoid system and GnRH-I in the forebrain of the anuran amphibian Rana esculenta. Endocrinology (2008) 149:2149-58. doi:10.1210/en.2007-1357.
    • (2008) Endocrinology , vol.149 , pp. 2149-2158
    • Meccariello, R.1    Franzoni, M.F.2    Chianese, R.3    Cottone, E.4    Scarpa, D.5    Donna, D.6
  • 29
    • 27644475828 scopus 로고    scopus 로고
    • The endocannabinoid system in the brain of Carassius auratus and its possible role in the control of food intake
    • doi:10.1111/j.1471-4159.2005.03406.x
    • Valenti M, Cottone E, Martinez R, De Pedro N, Rubio M, Viveros MP, et al. The endocannabinoid system in the brain of Carassius auratus and its possible role in the control of food intake. J Neurochem (2005) 95(3):662-72. doi:10.1111/j.1471-4159.2005.03406.x.
    • (2005) J Neurochem , vol.95 , Issue.3 , pp. 662-672
    • Valenti, M.1    Cottone, E.2    Martinez, R.3    De Pedro, N.4    Rubio, M.5    Viveros, M.P.6
  • 30
    • 32344440853 scopus 로고    scopus 로고
    • Distribution of cannabinoid receptor 1 in the CNS of zebrafish
    • doi:10.1016/j.neuroscience.2005.10.069
    • Lam CS, Rastegar S, Strähle U. Distribution of cannabinoid receptor 1 in the CNS of zebrafish. Neuroscience (2006) 138(1):83-95. doi:10.1016/j.neuroscience.2005.10.069.
    • (2006) Neuroscience , vol.138 , Issue.1 , pp. 83-95
    • Lam, C.S.1    Rastegar, S.2    Strähle, U.3
  • 31
    • 33645221146 scopus 로고    scopus 로고
    • Endocannabinoid system in Xenopus laevis development: CB1 receptor dynamics
    • doi:10.1016/j.febslet.2006.02.057
    • Migliarini B, Marucci G, GhelfiF, Carnevali O. Endocannabinoid system in Xenopus laevis development: CB1 receptor dynamics. FEBS Lett (2006) 580(8):1941-5. doi:10.1016/j.febslet.2006.02.057.
    • (2006) FEBS Lett , vol.580 , Issue.8 , pp. 1941-1945
    • Migliarini, B.1    Marucci, G.2    Ghelfi, F.3    Carnevali, O.4
  • 32
    • 33645453045 scopus 로고    scopus 로고
    • Type-1 cannabinoid receptor expression in the frog, Rana esculenta, tissues: a possible involvement in the regulation of testicular activity
    • doi:10.1002/mrd.20434
    • Meccariello R, Chianese R, Cacciola G, Cobellis G, Pierantoni R, Fasano S. Type-1 cannabinoid receptor expression in the frog, Rana esculenta, tissues: a possible involvement in the regulation of testicular activity. Mol Reprod Dev (2006) 73:551-8. doi:10.1002/mrd.20434.
    • (2006) Mol Reprod Dev , vol.73 , pp. 551-558
    • Meccariello, R.1    Chianese, R.2    Cacciola, G.3    Cobellis, G.4    Pierantoni, R.5    Fasano, S.6
  • 33
    • 81155159708 scopus 로고    scopus 로고
    • Anandamide modulates the expression of GnRH-II and GnRHRs in frog, Rana esculenta, diencephalon
    • doi:10.1016/j.ygcen.2011.07.001
    • Chianese R, Ciaramella V, Fasano S, Pierantoni R, Meccariello R. Anandamide modulates the expression of GnRH-II and GnRHRs in frog, Rana esculenta, diencephalon. Gen Comp Endocrinol (2011) 173:389-95. doi:10.1016/j.ygcen.2011.07.001.
    • (2011) Gen Comp Endocrinol , vol.173 , pp. 389-395
    • Chianese, R.1    Ciaramella, V.2    Fasano, S.3    Pierantoni, R.4    Meccariello, R.5
  • 34
    • 17044438211 scopus 로고    scopus 로고
    • Profiling neurotransmitter receptor expression in mouse gonadotropin-releasing hormone neurons using green fluorescent protein-promoter transgenics and microarrays
    • doi:10.1016/j.neuroscience.2005.01.035
    • Todman MG, Han SK, Herbison AE. Profiling neurotransmitter receptor expression in mouse gonadotropin-releasing hormone neurons using green fluorescent protein-promoter transgenics and microarrays. Neuroscience (2005) 132:703-12. doi:10.1016/j.neuroscience.2005.01.035.
    • (2005) Neuroscience , vol.132 , pp. 703-712
    • Todman, M.G.1    Han, S.K.2    Herbison, A.E.3
  • 35
    • 33646571242 scopus 로고    scopus 로고
    • Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain
    • doi:10.1016/j.neuroscience.2006.02.074
    • Cristino L, De Petrocellis L, Pryce G, Baker D, Guglielmotti V, Di Marzo V. Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain. Neuroscience (2006) 139:1405-15. doi:10.1016/j.neuroscience.2006.02.074.
    • (2006) Neuroscience , vol.139 , pp. 1405-1415
    • Cristino, L.1    De Petrocellis, L.2    Pryce, G.3    Baker, D.4    Guglielmotti, V.5    Di Marzo, V.6
  • 36
    • 24944536673 scopus 로고    scopus 로고
    • Regulation of gonadotropin-releasing hormone secretion by cannabinoids
    • doi:10.1210/en.2004-1672
    • Gammon CM, Freeman GM Jr, Xie W, Petersen SL, Wetsel WC. Regulation of gonadotropin-releasing hormone secretion by cannabinoids. Endocrinology (2005) 146(10):4491-9. doi:10.1210/en.2004-1672.
    • (2005) Endocrinology , vol.146 , Issue.10 , pp. 4491-4499
    • Gammon, C.M.1    Freeman Jr., G.M.2    Xie, W.3    Petersen, S.L.4    Wetsel, W.C.5
  • 37
    • 78649837310 scopus 로고    scopus 로고
    • Retrograde endocannabinoid signaling reduces GABA-ergic synaptic transmission to gonadotropin-releasing hormone neurons
    • doi:10.1210/en.2010-0638
    • Farkas I, Kallo' I, Deli L, Vida B, Hrabovszky E, Fekete C, et al. Retrograde endocannabinoid signaling reduces GABA-ergic synaptic transmission to gonadotropin-releasing hormone neurons. Endocrinology (2010) 151:5818-29. doi:10.1210/en.2010-0638.
    • (2010) Endocrinology , vol.151 , pp. 5818-5829
    • Farkas, I.1    Kallo', I.2    Deli, L.3    Vida, B.4    Hrabovszky, E.5    Fekete, C.6
  • 39
    • 42249084073 scopus 로고    scopus 로고
    • Endocannabinoids affect the reproductive functions in teleosts and amphibians
    • doi:10.1016/j.mce.2008.01.025
    • Cottone E, Guastalla A, Mackie K, Franzoni MF. Endocannabinoids affect the reproductive functions in teleosts and amphibians. Mol Cell Endocrinol (2008) 286:S41-5. doi:10.1016/j.mce.2008.01.025.
    • (2008) Mol Cell Endocrinol , vol.286
    • Cottone, E.1    Guastalla, A.2    Mackie, K.3    Franzoni, M.F.4
  • 40
    • 84885357376 scopus 로고    scopus 로고
    • Environmental and neuroendocrine control of fish reproduction
    • Garcia-Ayala A, Penalver JM, Chavez-Pozo E editors. Kerala: Research Signpost
    • Cardinaletti G, Franzoni MF, Palermo FA, et al. Environmental and neuroendocrine control of fish reproduction. In: Garcia-Ayala A, Penalver JM, Chavez-Pozo E editors. Recent Advances in Fish Reproduction Biology. Kerala: Research Signpost (2010). p. 65-87.
    • (2010) Recent Advances in Fish Reproduction Biology , pp. 65-87
    • Cardinaletti, G.1    Franzoni, M.F.2    Palermo, F.A.3
  • 42
    • 79959228560 scopus 로고    scopus 로고
    • Depolarising and hyperpolarising actions of GABA(A) receptor activation on gonadotrophin-releasing hormone neurones: towards an emerging consensus
    • doi:10.1111/j.1365-2826.2011.02145.x
    • Herbison AE, Moenter SM. Depolarising and hyperpolarising actions of GABA(A) receptor activation on gonadotrophin-releasing hormone neurones: towards an emerging consensus. Neuroendocrinol (2011) 23(7):557-69. doi:10.1111/j.1365-2826.2011.02145.x.
    • (2011) Neuroendocrinol , vol.23 , Issue.7 , pp. 557-569
    • Herbison, A.E.1    Moenter, S.M.2
  • 43
    • 84885969095 scopus 로고    scopus 로고
    • Afferent neuronal control of type-I gonadotropin releasing hormone neurons in the human
    • doi:10.3389/fendo.2013.00130
    • Hrabovszky E, Liposits Z. Afferent neuronal control of type-I gonadotropin releasing hormone neurons in the human. Front Endocrinol (2013) 4:130. doi:10.3389/fendo.2013.00130.
    • (2013) Front Endocrinol , vol.4 , pp. 130
    • Hrabovszky, E.1    Liposits, Z.2
  • 44
    • 0342841135 scopus 로고    scopus 로고
    • Identification of endocannabinoids and cannabinoid CB(1) receptor mRNA in the pituitary gland
    • doi:10.1159/000054468
    • González S, Manzanares J, Berrendero F, Wenger T, Corchero J, Bisogno T, et al. Identification of endocannabinoids and cannabinoid CB(1) receptor mRNA in the pituitary gland. Neuroendocrinology (1999) 70:137-45. doi:10.1159/000054468.
    • (1999) Neuroendocrinology , vol.70 , pp. 137-145
    • González, S.1    Manzanares, J.2    Berrendero, F.3    Wenger, T.4    Corchero, J.5    Bisogno, T.6
  • 45
    • 0023551235 scopus 로고
    • Effects of delta-9-tetrahydrocannabinol on the hypothalamic-pituitary control of luteinizing hormone and follicle-stimulating hormone secretion in adult male rats
    • doi:10.1159/000124870
    • Wenger T, Rettori V, Snyder GD, Dalterio S, McCann SM. Effects of delta-9-tetrahydrocannabinol on the hypothalamic-pituitary control of luteinizing hormone and follicle-stimulating hormone secretion in adult male rats. Neuroendocrinology (1987) 46(6):488-93. doi:10.1159/000124870.
    • (1987) Neuroendocrinology , vol.46 , Issue.6 , pp. 488-493
    • Wenger, T.1    Rettori, V.2    Snyder, G.D.3    Dalterio, S.4    McCann, S.M.5
  • 46
    • 0034353767 scopus 로고    scopus 로고
    • Decreased cannabinoid CB1 receptor mRNA levels and immunoreactivity in pituitary hyperplasia induced by prolonged exposure to estrogens
    • doi:10.1023/A:1012874029689
    • González S, Mauriello-Romanazzi G, Berrendero F, Ramos JA, Franzoni MF, Fernández-Ruiz J. Decreased cannabinoid CB1 receptor mRNA levels and immunoreactivity in pituitary hyperplasia induced by prolonged exposure to estrogens. Pituitary (2000) 3(4):221-6. doi:10.1023/A:1012874029689.
    • (2000) Pituitary , vol.3 , Issue.4 , pp. 221-226
    • González, S.1    Mauriello-Romanazzi, G.2    Berrendero, F.3    Ramos, J.A.4    Franzoni, M.F.5    Fernández-Ruiz, J.6
  • 47
    • 17844379461 scopus 로고    scopus 로고
    • Normal human pituitary gland and pituitary adenomas express cannabinoid receptor type 1 and synthesize endogenous cannabinoids: first evidence for a direct role of cannabinoids on hormone modulation at the human pituitary level
    • doi:10.1210/jc.86.6.2687
    • Pagotto U, Marsicano G, Fezza F, Theodoropoulou M, Grübler Y, Stalla J, et al. Normal human pituitary gland and pituitary adenomas express cannabinoid receptor type 1 and synthesize endogenous cannabinoids: first evidence for a direct role of cannabinoids on hormone modulation at the human pituitary level. J Clin Endocrinol Metab (2001) 86(6):2687-96. doi:10.1210/jc.86.6.2687.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.6 , pp. 2687-2696
    • Pagotto, U.1    Marsicano, G.2    Fezza, F.3    Theodoropoulou, M.4    Grübler, Y.5    Stalla, J.6
  • 48
    • 0036123612 scopus 로고    scopus 로고
    • Relationships between CB1 cannabinoid receptors and pituitary endocrine cells in Xenopus laevis: an immunohistochemical study
    • doi:10.1006/gcen.2001.7720
    • Cesa R, Guastalla A, Cottone E, Mackie K, Beltramo M, Franzoni MF. Relationships between CB1 cannabinoid receptors and pituitary endocrine cells in Xenopus laevis: an immunohistochemical study. Gen Comp Endocrinol (2002) 125:17-24. doi:10.1006/gcen.2001.7720.
    • (2002) Gen Comp Endocrinol , vol.125 , pp. 17-24
    • Cesa, R.1    Guastalla, A.2    Cottone, E.3    Mackie, K.4    Beltramo, M.5    Franzoni, M.F.6
  • 49
    • 77953395004 scopus 로고    scopus 로고
    • An endocannabinoid system is localized to the hypophysial pars tuberalis of Syrian hamsters and responds to photoperiodic changes
    • doi:10.1007/s00441-010-0930-7
    • Yasuo S, Koch M, Schmidt H, Ziebell S, Bojunga J, Geisslinger G, et al. An endocannabinoid system is localized to the hypophysial pars tuberalis of Syrian hamsters and responds to photoperiodic changes. Cell Tissue Res (2010) 340:127-36. doi:10.1007/s00441-010-0930-7.
    • (2010) Cell Tissue Res , vol.340 , pp. 127-136
    • Yasuo, S.1    Koch, M.2    Schmidt, H.3    Ziebell, S.4    Bojunga, J.5    Geisslinger, G.6
  • 51
    • 67651100794 scopus 로고    scopus 로고
    • Fluctuation in anandamide levels from ovulation to early pregnancy in in-vitro fertilization-embryo transfer women, and its hormonal regulation
    • doi:10.1093/humrep/dep065
    • El-Talatini MR, Taylor AH, Konje JC. Fluctuation in anandamide levels from ovulation to early pregnancy in in-vitro fertilization-embryo transfer women, and its hormonal regulation. Hum Reprod (2009) 24:1989-98. doi:10.1093/humrep/dep065.
    • (2009) Hum Reprod , vol.24 , pp. 1989-1998
    • El-Talatini, M.R.1    Taylor, A.H.2    Konje, J.C.3
  • 52
    • 84881607274 scopus 로고    scopus 로고
    • Anandamide levels fluctuate in the bovine oviduct during the oestrous cycle
    • doi:10.1371/journal.pone.0072521
    • Gervasi MG, Marczylo TH, Lam PM, Rana S, Franchi AM, Konje JC, et al. Anandamide levels fluctuate in the bovine oviduct during the oestrous cycle. PLoS One (2013) 8:e72521. doi:10.1371/journal.pone.0072521.
    • (2013) PLoS One , vol.8
    • Gervasi, M.G.1    Marczylo, T.H.2    Lam, P.M.3    Rana, S.4    Franchi, A.M.5    Konje, J.C.6
  • 53
    • 0028931849 scopus 로고
    • An ammino-terminal variant of the central cannabinoid receptor resulting from alternative splicing
    • doi:10.1074/jbc.270.8.3726
    • Shire D, Carillon C, Kaghad M, Calandra B, Rinaldi-Carmona M, Le Fur G, et al. An ammino-terminal variant of the central cannabinoid receptor resulting from alternative splicing. J Biol Chem (1995) 270:3726-31. doi:10.1074/jbc.270.8.3726.
    • (1995) J Biol Chem , vol.270 , pp. 3726-3731
    • Shire, D.1    Carillon, C.2    Kaghad, M.3    Calandra, B.4    Rinaldi-Carmona, M.5    Le Fur, G.6
  • 54
    • 11144263163 scopus 로고    scopus 로고
    • Identification and characterization of a novel splice variant of the human CB1 receptor
    • doi:10.1016/j.febslet.2004.11.085
    • Ryberg E, Vu HK, Larsson N, Groblewski T, Hjorth S, Elebring T, et al. Identification and characterization of a novel splice variant of the human CB1 receptor. FEBS Lett (2005) 579:259-64. doi:10.1016/j.febslet.2004.11.085.
    • (2005) FEBS Lett , vol.579 , pp. 259-264
    • Ryberg, E.1    Vu, H.K.2    Larsson, N.3    Groblewski, T.4    Hjorth, S.5    Elebring, T.6
  • 55
    • 67650486960 scopus 로고    scopus 로고
    • Species differences in cannabinoid receptor 2 (CNR2 gene): identification of novel human and rodent CB2 isoforms, differential tissue expression and regulation by cannabinoid receptor ligands
    • doi:10.1111/j.1601-183X.2009.00498.x
    • Liu QR, Pan CH, Hishimoto A, Li CY, Xi ZX, Llorente-Berzal A, et al. Species differences in cannabinoid receptor 2 (CNR2 gene): identification of novel human and rodent CB2 isoforms, differential tissue expression and regulation by cannabinoid receptor ligands. Genes Brain Behav (2009) 8:519-30. doi:10.1111/j.1601-183X.2009.00498.x.
    • (2009) Genes Brain Behav , vol.8 , pp. 519-530
    • Liu, Q.R.1    Pan, C.H.2    Hishimoto, A.3    Li, C.Y.4    Xi, Z.X.5    Llorente-Berzal, A.6
  • 56
    • 33747062387 scopus 로고    scopus 로고
    • Jekyll and Hyde: two faces of cannabinoid signaling in male and female fertility
    • doi:10.1210/er.2006-0006
    • Wang H, Dey SK, Maccarrone M. Jekyll and Hyde: two faces of cannabinoid signaling in male and female fertility. Endocr Rev (2006) 27:427-48. doi:10.1210/er.2006-0006.
    • (2006) Endocr Rev , vol.27 , pp. 427-448
    • Wang, H.1    Dey, S.K.2    Maccarrone, M.3
  • 57
    • 42249092991 scopus 로고    scopus 로고
    • The endocannabinoid system in vertebrate male reproduction: a comparative overview
    • doi:10.1016/j.mce.2008.01.004
    • Cacciola G, Chioccarelli T, Ricci G, Meccariello R, Fasano S, Pierantoni R, et al. The endocannabinoid system in vertebrate male reproduction: a comparative overview. Mol Cell Endocrinol (2008) 286:S24-30. doi:10.1016/j.mce.2008.01.004.
    • (2008) Mol Cell Endocrinol , vol.286
    • Cacciola, G.1    Chioccarelli, T.2    Ricci, G.3    Meccariello, R.4    Fasano, S.5    Pierantoni, R.6
  • 58
    • 67651172831 scopus 로고    scopus 로고
    • CB1 activity in male reproduction: mammalian and nonmammalian animal models
    • doi:10.1016/S0083-6729(09)81014-5
    • Pierantoni R, Cobellis G, Meccariello R, Cacciola G, Chianese R, Chioccarelli T, et al. CB1 activity in male reproduction: mammalian and nonmammalian animal models. Vitam Horm (2009) 81:367-87. doi:10.1016/S0083-6729(09)81014-5.
    • (2009) Vitam Horm , vol.81 , pp. 367-387
    • Pierantoni, R.1    Cobellis, G.2    Meccariello, R.3    Cacciola, G.4    Chianese, R.5    Chioccarelli, T.6
  • 59
    • 65449137982 scopus 로고    scopus 로고
    • Testicular gonadotropin-releasing hormone activity, progression of spermatogenesis, and sperm transport in vertebrates
    • doi:10.1111/j.1749-6632.2008.03617.x
    • Pierantoni R, Cobellis G, Meccariello R, Cacciola G, Chianese R, Chioccarelli T, et al. Testicular gonadotropin-releasing hormone activity, progression of spermatogenesis, and sperm transport in vertebrates. Ann N Y Acad Sci (2009) 1163:279-91. doi:10.1111/j.1749-6632.2008.03617.x.
    • (2009) Ann N Y Acad Sci , vol.1163 , pp. 279-291
    • Pierantoni, R.1    Cobellis, G.2    Meccariello, R.3    Cacciola, G.4    Chianese, R.5    Chioccarelli, T.6
  • 60
    • 58249085755 scopus 로고    scopus 로고
    • Low type I cannabinoid receptor levels characterize placental villous in labouring delivery
    • doi:10.1016/j.placenta.2008.11.018
    • Acone G, Trabucco E, Colacurci N, Cobellis L, Mackie K, Meccariello R, et al. Low type I cannabinoid receptor levels characterize placental villous in labouring delivery. Placenta (2009) 30:203-5. doi:10.1016/j.placenta.2008.11.018.
    • (2009) Placenta , vol.30 , pp. 203-205
    • Acone, G.1    Trabucco, E.2    Colacurci, N.3    Cobellis, L.4    Mackie, K.5    Meccariello, R.6
  • 61
    • 65649101233 scopus 로고    scopus 로고
    • Endocannabinoid system in first trimester placenta: low FAAH and high CB1 expression characterize spontaneous miscarriage
    • doi:10.1016/j.placenta.2009.03.015
    • Trabucco E, Acone G, Marenna A, Pierantoni R, Cacciola G, Chioccarelli T, et al. Endocannabinoid system in first trimester placenta: low FAAH and high CB1 expression characterize spontaneous miscarriage. Placenta (2009) 30:516-22. doi:10.1016/j.placenta.2009.03.015.
    • (2009) Placenta , vol.30 , pp. 516-522
    • Trabucco, E.1    Acone, G.2    Marenna, A.3    Pierantoni, R.4    Cacciola, G.5    Chioccarelli, T.6
  • 64
    • 33845450355 scopus 로고    scopus 로고
    • Changes of gonadal CB1 cannabinoid receptor mRNA in the gilthead seabream, Sparus aurata, during sex reversal
    • doi:10.1016/j.ygcen.2006.09.001
    • Ruggeri B, Soverchia L, Mosconi G, Franzoni MF, Cottone E, Polzonetti-Magni AM. Changes of gonadal CB1 cannabinoid receptor mRNA in the gilthead seabream, Sparus aurata, during sex reversal. Gen Comp Endocrinol (2007) 150:263-9. doi:10.1016/j.ygcen.2006.09.001.
    • (2007) Gen Comp Endocrinol , vol.150 , pp. 263-269
    • Ruggeri, B.1    Soverchia, L.2    Mosconi, G.3    Franzoni, M.F.4    Cottone, E.5    Polzonetti-Magni, A.M.6
  • 65
    • 33745370628 scopus 로고    scopus 로고
    • Endocannabinoid system in frog and rodent testis: type-1 cannabinoid receptor and fatty acid amide hydrolase activity in male germ cells
    • doi:10.1095/biolreprod.106.051730
    • Cobellis G, Cacciola G, Scarpa D, Meccariello R, Chianese R, Franzoni MF, et al. Endocannabinoid system in frog and rodent testis: type-1 cannabinoid receptor and fatty acid amide hydrolase activity in male germ cells. Biol Reprod (2006) 75:82-9. doi:10.1095/biolreprod.106.051730.
    • (2006) Biol Reprod , vol.75 , pp. 82-89
    • Cobellis, G.1    Cacciola, G.2    Scarpa, D.3    Meccariello, R.4    Chianese, R.5    Franzoni, M.F.6
  • 66
    • 34249068505 scopus 로고    scopus 로고
    • Cloning of type 1 cannabinoid receptor in Rana esculenta reveals differences between genomic sequence and cDNA
    • doi:10.1111/j.1742-4658.2007.05824.x
    • Meccariello R, Chianese R, Cobellis G, Pierantoni R, Fasano S. Cloning of type 1 cannabinoid receptor in Rana esculenta reveals differences between genomic sequence and cDNA. FEBS J (2007) 274:2909-20. doi:10.1111/j.1742-4658.2007.05824.x.
    • (2007) FEBS J , vol.274 , pp. 2909-2920
    • Meccariello, R.1    Chianese, R.2    Cobellis, G.3    Pierantoni, R.4    Fasano, S.5
  • 67
    • 42249102759 scopus 로고    scopus 로고
    • Non-mammalian vertebrate models and the endocannabinoid system: relationships with gonadotropin-releasing hormone
    • doi:10.1016/j.mce.2008.01.009
    • Chianese R, Cobellis G, Pierantoni R, Fasano S, Meccariello R. Non-mammalian vertebrate models and the endocannabinoid system: relationships with gonadotropin-releasing hormone. Mol Cell Endocrinol (2008) 286:S46-51. doi:10.1016/j.mce.2008.01.009.
    • (2008) Mol Cell Endocrinol , vol.286
    • Chianese, R.1    Cobellis, G.2    Pierantoni, R.3    Fasano, S.4    Meccariello, R.5
  • 68
    • 84865153943 scopus 로고    scopus 로고
    • Meccariello anandamide regulates the expression of GnRH1, GnRH2, and GnRH-Rs in frog testis
    • doi:10.1152/ajpendo.00086.2012
    • Chianese R, Ciaramella V, Scarpa D, Fasano S, Pierantoni R. Meccariello anandamide regulates the expression of GnRH1, GnRH2, and GnRH-Rs in frog testis. Am J Physiol Endocrinol Metab (2012) 303:E475-87. doi:10.1152/ajpendo.00086.2012.
    • (2012) Am J Physiol Endocrinol Metab , vol.303
    • Chianese, R.1    Ciaramella, V.2    Scarpa, D.3    Fasano, S.4    Pierantoni, R.5
  • 69
    • 79960987094 scopus 로고    scopus 로고
    • Expression of cannabinoid receptor 1 in mouse testes
    • doi:10.1080/014850190898845
    • Gye MC, Kang HH, Kang HJ. Expression of cannabinoid receptor 1 in mouse testes. Arch Androl (2005) 51:247-55. doi:10.1080/014850190898845.
    • (2005) Arch Androl , vol.51 , pp. 247-255
    • Gye, M.C.1    Kang, H.H.2    Kang, H.J.3
  • 70
    • 0037227333 scopus 로고    scopus 로고
    • Anandamide activity and degradation are regulated by early postnatal aging and follicle-stimulating hormone in mouse Sertoli cells
    • doi:10.1210/en.2002-220544
    • Maccarrone M, Cecconi S, Rossi G, Battista N, Pauselli R, Finazzi-Agrò A. Anandamide activity and degradation are regulated by early postnatal aging and follicle-stimulating hormone in mouse Sertoli cells. Endocrinology (2003) 144:20-8. doi:10.1210/en.2002-220544.
    • (2003) Endocrinology , vol.144 , pp. 20-28
    • Maccarrone, M.1    Cecconi, S.2    Rossi, G.3    Battista, N.4    Pauselli, R.5    Finazzi-Agrò, A.6
  • 71
    • 33847027343 scopus 로고    scopus 로고
    • Follicle-stimulating hormone activates fatty acid amide hydrolase by protein kinase A and aromatase-dependent pathways in mouse primary Sertoli cells
    • doi:10.1210/en.2006-0969
    • Rossi G, Gasperi V, Paro R, Barsacchi D, Cecconi S, Maccarrone M. Follicle-stimulating hormone activates fatty acid amide hydrolase by protein kinase A and aromatase-dependent pathways in mouse primary Sertoli cells. Endocrinology (2007) 148:1431-9. doi:10.1210/en.2006-0969.
    • (2007) Endocrinology , vol.148 , pp. 1431-1439
    • Rossi, G.1    Gasperi, V.2    Paro, R.3    Barsacchi, D.4    Cecconi, S.5    Maccarrone, M.6
  • 72
    • 53349108792 scopus 로고    scopus 로고
    • Expression of type-1 cannabinoid receptor during rat postnatal testicular development: possible involvement in adult leydig cell differentiation
    • doi:10.1095/biolreprod.108.070128
    • Cacciola G, Chioccarelli T, Mackie K, Meccariello R, Ledent C, Fasano S, et al. Expression of type-1 cannabinoid receptor during rat postnatal testicular development: possible involvement in adult leydig cell differentiation. Biol Reprod (2008) 79:758-65. doi:10.1095/biolreprod.108.070128.
    • (2008) Biol Reprod , vol.79 , pp. 758-765
    • Cacciola, G.1    Chioccarelli, T.2    Mackie, K.3    Meccariello, R.4    Ledent, C.5    Fasano, S.6
  • 73
    • 67650488942 scopus 로고    scopus 로고
    • The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis
    • doi:10.1073/pnas.0812789106
    • Grimaldi P, Orlando P, Di Siena S, Lolicato F, Petrosino S, Bisogno T, et al. The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis. Proc Natl Acad Sci U S A (2009) 106:11131-6. doi:10.1073/pnas.0812789106.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 11131-11136
    • Grimaldi, P.1    Orlando, P.2    Di Siena, S.3    Lolicato, F.4    Petrosino, S.5    Bisogno, T.6
  • 74
    • 77957261185 scopus 로고    scopus 로고
    • Cannabinoid receptor 1 influences chromatin remodeling in mouse spermatids by affecting content of transition protein 2 mRNA and histone displacement
    • doi:10.1210/en.2010-0133
    • Chioccarelli T, Cacciola G, Altucci L, Lewis SE, Simon L, Ricci G, et al. Cannabinoid receptor 1 influences chromatin remodeling in mouse spermatids by affecting content of transition protein 2 mRNA and histone displacement. Endocrinology (2010) 151:5017-29. doi:10.1210/en.2010-0133.
    • (2010) Endocrinology , vol.151 , pp. 5017-5029
    • Chioccarelli, T.1    Cacciola, G.2    Altucci, L.3    Lewis, S.E.4    Simon, L.5    Ricci, G.6
  • 75
    • 0027982533 scopus 로고
    • Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction
    • doi:10.1073/pnas.91.16.7678
    • Schuel H, Goldstein E, Mechoulam R, Zimmerman AM, Zimmerman S. Anandamide (arachidonylethanolamide), a brain cannabinoid receptor agonist, reduces sperm fertilizing capacity in sea urchins by inhibiting the acrosome reaction. Proc Natl Acad Sci U S A (1994) 91:7678-82. doi:10.1073/pnas.91.16.7678.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 7678-7682
    • Schuel, H.1    Goldstein, E.2    Mechoulam, R.3    Zimmerman, A.M.4    Zimmerman, S.5
  • 76
    • 34547120212 scopus 로고    scopus 로고
    • Endocannabinoid control of sperm motility: the role of epididymus
    • doi:10.1016/j.ygcen.2007.02.003
    • Ricci G, Cacciola G, Altucci L, Meccariello R, Pierantoni R, Fasano S, et al. Endocannabinoid control of sperm motility: the role of epididymus. Gen Comp Endocrinol (2007) 153:320-2. doi:10.1016/j.ygcen.2007.02.003.
    • (2007) Gen Comp Endocrinol , vol.153 , pp. 320-322
    • Ricci, G.1    Cacciola, G.2    Altucci, L.3    Meccariello, R.4    Pierantoni, R.5    Fasano, S.6
  • 77
    • 77950367259 scopus 로고    scopus 로고
    • A gradient of 2-arachidonoylglycerol regulates mouse epididymal sperm cell start-up
    • doi:10.1095/biolreprod.109.079210
    • Cobellis G, Ricci G, Cacciola G, Orlando P, Petrosino S, Cascio MG, et al. A gradient of 2-arachidonoylglycerol regulates mouse epididymal sperm cell start-up. Biol Reprod (2010) 82:451-8. doi:10.1095/biolreprod.109.079210.
    • (2010) Biol Reprod , vol.82 , pp. 451-458
    • Cobellis, G.1    Ricci, G.2    Cacciola, G.3    Orlando, P.4    Petrosino, S.5    Cascio, M.G.6
  • 78
    • 80051560797 scopus 로고    scopus 로고
    • Effect of capacitation on the endocannabinoid system of mouse sperm
    • doi:10.1016/j.mce.2011.01.022
    • Catanzaro G, Battista N, Rossi G, Di Tommaso M, Pucci M, Pirazzi V, et al. Effect of capacitation on the endocannabinoid system of mouse sperm. Mol Cell Endocrinol (2011) 343:88-92. doi:10.1016/j.mce.2011.01.022.
    • (2011) Mol Cell Endocrinol , vol.343 , pp. 88-92
    • Catanzaro, G.1    Battista, N.2    Rossi, G.3    Di Tommaso, M.4    Pucci, M.5    Pirazzi, V.6
  • 79
    • 79959569824 scopus 로고    scopus 로고
    • Effects of chronic bhang (cannabis) administration on the reproductive system of male mice
    • doi:10.1002/bdrb.20295
    • Banerjee A, Singh A, Srivastava P, Turner H, Krishna A. Effects of chronic bhang (cannabis) administration on the reproductive system of male mice. Birth Defects Res B Dev Reprod Toxicol (2011) 92:195-205. doi:10.1002/bdrb.20295.
    • (2011) Birth Defects Res B Dev Reprod Toxicol , vol.92 , pp. 195-205
    • Banerjee, A.1    Singh, A.2    Srivastava, P.3    Turner, H.4    Krishna, A.5
  • 80
    • 79951825469 scopus 로고    scopus 로고
    • Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation
    • doi:10.1371/journal.pone.0016993
    • Gervasi MG, Osycka-Salut C, Caballero J, Vazquez-Levin M, Pereyra E, Billi S, et al. Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation. PLoS One (2011) 6:e16993. doi:10.1371/journal.pone.0016993.
    • (2011) PLoS One , vol.6
    • Gervasi, M.G.1    Osycka-Salut, C.2    Caballero, J.3    Vazquez-Levin, M.4    Pereyra, E.5    Billi, S.6
  • 81
    • 27644572736 scopus 로고    scopus 로고
    • Characterization of the endocannabinoid system in boar spermatozoa and implications for sperm capacitation and acrosome reaction
    • doi:10.1242/jcs.02536
    • Maccarrone M, Barboni B, Paradisi A, Bernabò N, Gasperi V, Pistilli MG, et al. Characterization of the endocannabinoid system in boar spermatozoa and implications for sperm capacitation and acrosome reaction. J Cell Sci (2005) 118:4393-404. doi:10.1242/jcs.02536.
    • (2005) J Cell Sci , vol.118 , pp. 4393-4404
    • Maccarrone, M.1    Barboni, B.2    Paradisi, A.3    Bernabò, N.4    Gasperi, V.5    Pistilli, M.G.6
  • 82
    • 0036836648 scopus 로고    scopus 로고
    • Evidence that anandamide-signalling regulates human sperm functions required for fertilization
    • doi:10.1002/mrd.90021
    • Schuel H, Burkman LJ, Lippes J, Crickard K, Mahony MC, Giuffrida A, et al. Evidence that anandamide-signalling regulates human sperm functions required for fertilization. Mol Reprod Dev (2002) 63:376-87. doi:10.1002/mrd.90021.
    • (2002) Mol Reprod Dev , vol.63 , pp. 376-387
    • Schuel, H.1    Burkman, L.J.2    Lippes, J.3    Crickard, K.4    Mahony, M.C.5    Giuffrida, A.6
  • 83
    • 14044279352 scopus 로고    scopus 로고
    • Human sperm express cannabinoid receptor Cb1, the activation of which inhibits motility, acrosome reaction, and mitochondrial function
    • doi:10.1210/jc.2004-1287
    • Rossato M, Ion Popa F, Ferigo M, Clari G, Foresta C. Human sperm express cannabinoid receptor Cb1, the activation of which inhibits motility, acrosome reaction, and mitochondrial function. J Clin Endocrinol Metab (2005) 90:984-91. doi:10.1210/jc.2004-1287.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 984-991
    • Rossato, M.1    Ion Popa, F.2    Ferigo, M.3    Clari, G.4    Foresta, C.5
  • 84
    • 70349328116 scopus 로고    scopus 로고
    • Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability
    • doi:10.1210/en.2009-0057
    • Francavilla F, Battista N, Barbonetti A, Vassallo MR, Rapino C, Antonangelo C, et al. Characterization of the endocannabinoid system in human spermatozoa and involvement of transient receptor potential vanilloid 1 receptor in their fertilizing ability. Endocrinology (2009) 150:4692-700. doi:10.1210/en.2009-0057.
    • (2009) Endocrinology , vol.150 , pp. 4692-4700
    • Francavilla, F.1    Battista, N.2    Barbonetti, A.3    Vassallo, M.R.4    Rapino, C.5    Antonangelo, C.6
  • 85
    • 84880553007 scopus 로고    scopus 로고
    • Anandamide modulates human sperm motility: implications for men with asthenozoospermia and oligoasthenoteratozoospermia
    • doi:10.1093/humrep/det232
    • Amoako AA, Marczylo TH, Marczylo EL, Elson J, Willets JM, Taylor AH, et al. Anandamide modulates human sperm motility: implications for men with asthenozoospermia and oligoasthenoteratozoospermia. Hum Reprod (2013) 28:2058-66. doi:10.1093/humrep/det232.
    • (2013) Hum Reprod , vol.28 , pp. 2058-2066
    • Amoako, A.A.1    Marczylo, T.H.2    Marczylo, E.L.3    Elson, J.4    Willets, J.M.5    Taylor, A.H.6
  • 86
    • 63449100550 scopus 로고    scopus 로고
    • Association of marijuana use and the incidence of testicular germ cell tumors
    • doi:10.1002/cncr.24159
    • Darling JR, Doody DR, Sun X, Trabert BL, Weiss NS, Chen C, et al. Association of marijuana use and the incidence of testicular germ cell tumors. Cancer (2009) 115:1215-23. doi:10.1002/cncr.24159.
    • (2009) Cancer , vol.115 , pp. 1215-1223
    • Darling, J.R.1    Doody, D.R.2    Sun, X.3    Trabert, B.L.4    Weiss, N.S.5    Chen, C.6
  • 88
    • 84867848400 scopus 로고    scopus 로고
    • Population-based case-control study of recreational drug use and testis cancer risk confirms an association between marijuana use and nonseminoma risk
    • doi:10.1002/cncr.27554
    • Lacson JC, Carroll JD, Tuazon E, Castelao EJ, Bernstein L, Cortessis VK. Population-based case-control study of recreational drug use and testis cancer risk confirms an association between marijuana use and nonseminoma risk. Cancer (2012) 118:5374-83. doi:10.1002/cncr.27554.
    • (2012) Cancer , vol.118 , pp. 5374-5383
    • Lacson, J.C.1    Carroll, J.D.2    Tuazon, E.3    Castelao, E.J.4    Bernstein, L.5    Cortessis, V.K.6
  • 89
    • 84893822143 scopus 로고    scopus 로고
    • The endocannabinoid system and sex steroid hormone-dependent cancers
    • doi:10.1155/2013/259676
    • Ayakannu T, Taylor AH, Marczylo TH, Willets JM, Konje JC. The endocannabinoid system and sex steroid hormone-dependent cancers. Int J Endocrinol (2013) 2013:259676. doi:10.1155/2013/259676.
    • (2013) Int J Endocrinol , vol.2013 , pp. 259676
    • Ayakannu, T.1    Taylor, A.H.2    Marczylo, T.H.3    Willets, J.M.4    Konje, J.C.5
  • 90
    • 84866177164 scopus 로고    scopus 로고
    • Long-term use of HU210 adversely affects spermatogenesis in rats by modulating the endocannabinoid system
    • doi:10.1111/j.1365-2605.2012.01259.x
    • Lewis SE, Paro R, Borriello L, Simon L, Robinson L, Dincer Z, et al. Long-term use of HU210 adversely affects spermatogenesis in rats by modulating the endocannabinoid system. Int J Androl (2012) 35:731-40. doi:10.1111/j.1365-2605.2012.01259.x.
    • (2012) Int J Androl , vol.35 , pp. 731-740
    • Lewis, S.E.1    Paro, R.2    Borriello, L.3    Simon, L.4    Robinson, L.5    Dincer, Z.6
  • 91
    • 84867647981 scopus 로고    scopus 로고
    • Differences in the endocannabinoid system of sperm from fertile and infertile men
    • doi:10.1371/journal.pone.0047704
    • Lewis SE, Rapino C, Di Tommaso M, Pucci M, Battista N, Paro R, et al. Differences in the endocannabinoid system of sperm from fertile and infertile men. PLoS One (2012) 7:e47704. doi:10.1371/journal.pone.0047704.
    • (2012) PLoS One , vol.7
    • Lewis, S.E.1    Rapino, C.2    Di Tommaso, M.3    Pucci, M.4    Battista, N.5    Paro, R.6
  • 92
    • 59949100369 scopus 로고    scopus 로고
    • Genetic loss of Faah compromises male fertility in mice
    • doi:10.1095/biolreprod.108.072736
    • Sun X, Wang H, Okabe M, Mackie K, Kingsley PJ, Marnett LJ, et al. Genetic loss of Faah compromises male fertility in mice. Biol Reprod (2009) 80:235-42. doi:10.1095/biolreprod.108.072736.
    • (2009) Biol Reprod , vol.80 , pp. 235-242
    • Sun, X.1    Wang, H.2    Okabe, M.3    Mackie, K.4    Kingsley, P.J.5    Marnett, L.J.6
  • 93
    • 84908622007 scopus 로고    scopus 로고
    • Hypothalamus-pituitary axis: an obligatory target for endocannabinoids to inhibit steroidogenesis in frog testis
    • doi:10.1016/j.ygcen.2014.02.010.
    • Chianese R, Ciaramella V, Fasano S, Pierantoni R, Meccariello R. Hypothalamus-pituitary axis: an obligatory target for endocannabinoids to inhibit steroidogenesis in frog testis. Gen Comp Endocrinol (2014). doi:10.1016/j.ygcen.2014.02.010.
    • (2014) Gen Comp Endocrinol
    • Chianese, R.1    Ciaramella, V.2    Fasano, S.3    Pierantoni, R.4    Meccariello, R.5
  • 94
    • 84890013614 scopus 로고    scopus 로고
    • Estrogens and spermiogenesis: new insights from type 1 cannabinoid receptor knockout mice
    • doi:10.1155/2013/501350
    • Cacciola G, Chioccarelli T, Fasano S, Pierantoni R, Cobellis G. Estrogens and spermiogenesis: new insights from type 1 cannabinoid receptor knockout mice. Int J Endocrinol (2013) 2013:501350. doi:10.1155/2013/501350.
    • (2013) Int J Endocrinol , vol.2013 , pp. 501350
    • Cacciola, G.1    Chioccarelli, T.2    Fasano, S.3    Pierantoni, R.4    Cobellis, G.5
  • 95
    • 84870676864 scopus 로고    scopus 로고
    • The faah gene is the first direct target of estrogen in the testis: role of histone demethylase LSD1
    • doi:10.1007/s00018-012-1074-6
    • Grimaldi P, Pucci M, Di Siena S, Di Giacomo D, Pirazzi V, Geremia R, et al. The faah gene is the first direct target of estrogen in the testis: role of histone demethylase LSD1. Cell Mol Life Sci (2012) 69:4177-90. doi:10.1007/s00018-012-1074-6.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 4177-4190
    • Grimaldi, P.1    Pucci, M.2    Di Siena, S.3    Di Giacomo, D.4    Pirazzi, V.5    Geremia, R.6
  • 96
    • 52949118528 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid receptor-1 confers heat resistance to male germ cells
    • doi:10.1016/j.fertnstert.2007.10.081
    • Mizrak SC, van Dissel-Emiliani FM. Transient receptor potential vanilloid receptor-1 confers heat resistance to male germ cells. Fertil Steril (2008) 90:1290-3. doi:10.1016/j.fertnstert.2007.10.081.
    • (2008) Fertil Steril , vol.90 , pp. 1290-1293
    • Mizrak, S.C.1    van Dissel-Emiliani, F.M.2
  • 97
    • 84884225858 scopus 로고    scopus 로고
    • Endocannabinoids and endovanilloids: a possible balance in the regulation of the testicular GnRH signalling
    • doi:10.1155/2013/904748
    • Chianese R, Ciaramella V, Scarpa D, Fasano S, Pierantoni R, Meccariello R. Endocannabinoids and endovanilloids: a possible balance in the regulation of the testicular GnRH signalling. Int J Endocrinol (2013) 2013:904748. doi:10.1155/2013/904748.
    • (2013) Int J Endocrinol , vol.2013 , pp. 904748
    • Chianese, R.1    Ciaramella, V.2    Scarpa, D.3    Fasano, S.4    Pierantoni, R.5    Meccariello, R.6
  • 99
    • 84883703415 scopus 로고    scopus 로고
    • Nuclear size as estrogen-responsive chromatin quality parameter of mouse spermatozoa
    • doi:10.1016/j.ygcen.2013.07.018
    • Cacciola G, Chioccarelli T, Altucci L, Viaggiano A, Fasano S, Pierantoni R, et al. Nuclear size as estrogen-responsive chromatin quality parameter of mouse spermatozoa. Gen Comp Endocrinol (2013) 193:201-9. doi:10.1016/j.ygcen.2013.07.018.
    • (2013) Gen Comp Endocrinol , vol.193 , pp. 201-209
    • Cacciola, G.1    Chioccarelli, T.2    Altucci, L.3    Viaggiano, A.4    Fasano, S.5    Pierantoni, R.6
  • 100
    • 2342558645 scopus 로고    scopus 로고
    • Transition nuclear proteins are required for normal chromatin condensation and functional sperm development
    • doi:10.1002/gene.20019
    • Zhao M, Shirley CR, Hayashi S, Marcon L, Mohapatra B, Suganuma R, et al. Transition nuclear proteins are required for normal chromatin condensation and functional sperm development. Genesis (2004) 38:200-13. doi:10.1002/gene.20019.
    • (2004) Genesis , vol.38 , pp. 200-213
    • Zhao, M.1    Shirley, C.R.2    Hayashi, S.3    Marcon, L.4    Mohapatra, B.5    Suganuma, R.6
  • 101
    • 1642353297 scopus 로고    scopus 로고
    • Transient DNA strand breaks during mouse and human spermiogenesis new insights in stage specificity and link to chromatin remodeling
    • doi:10.1095/biolreprod.103.022541
    • Marcon L, Boissonneault G. Transient DNA strand breaks during mouse and human spermiogenesis new insights in stage specificity and link to chromatin remodeling. Biol Reprod (2004) 70:910-8. doi:10.1095/biolreprod.103.022541.
    • (2004) Biol Reprod , vol.70 , pp. 910-918
    • Marcon, L.1    Boissonneault, G.2
  • 102
    • 0026084453 scopus 로고
    • Vertebrate protamine genes and histone-to-protamine replacement reaction
    • doi:10.1016/S0079-6603(08)60839-9
    • Oliva R, Dixon GH. Vertebrate protamine genes and histone-to-protamine replacement reaction. Prog Nucleic Acid Res Mol Biol (1991) 40:25-94. doi:10.1016/S0079-6603(08)60839-9.
    • (1991) Prog Nucleic Acid Res Mol Biol , vol.40 , pp. 25-94
    • Oliva, R.1    Dixon, G.H.2
  • 103
    • 13644270553 scopus 로고    scopus 로고
    • Establishment of male-specific epigenetic information
    • doi:10.1016/j.gene.2004.12.004
    • Rousseaux S, Caron C, Govin J, Lestrat C, Faure AK, Khochbin S. Establishment of male-specific epigenetic information. Gene (2005) 345:139-53. doi:10.1016/j.gene.2004.12.004.
    • (2005) Gene , vol.345 , pp. 139-153
    • Rousseaux, S.1    Caron, C.2    Govin, J.3    Lestrat, C.4    Faure, A.K.5    Khochbin, S.6
  • 104
    • 78650991459 scopus 로고    scopus 로고
    • Proteomics and the genetics of sperm chromatin condensation
    • doi:10.1038/aja.2010.65
    • Oliva R, Castillo J. Proteomics and the genetics of sperm chromatin condensation. Asian J Androl (2011) 13:24-30. doi:10.1038/aja.2010.65.
    • (2011) Asian J Androl , vol.13 , pp. 24-30
    • Oliva, R.1    Castillo, J.2
  • 105
    • 4544359564 scopus 로고    scopus 로고
    • Abnormalities and reduced reproductive potential of sperm from Tnp1-and Tnp2-null double mutant mice
    • doi:10.1095/biolreprod.104.029363
    • Shirley CR, Hayashi S, Mounsey S, Yanagimachi R, Meistrich ML. Abnormalities and reduced reproductive potential of sperm from Tnp1-and Tnp2-null double mutant mice. Biol Reprod (2004) 71:1220-9. doi:10.1095/biolreprod.104.029363.
    • (2004) Biol Reprod , vol.71 , pp. 1220-1229
    • Shirley, C.R.1    Hayashi, S.2    Mounsey, S.3    Yanagimachi, R.4    Meistrich, M.L.5
  • 106
    • 0034797470 scopus 로고    scopus 로고
    • Targeted disruption of the transition protein 2 gene affects sperm chromatin structure and reduces fertility in mice
    • doi:10.1128/MCB.21.21.7243-7255.2001
    • Zhao M, Shirley CR, Yu YE, Mohapatra B, Zhang Y, Unni E, et al. Targeted disruption of the transition protein 2 gene affects sperm chromatin structure and reduces fertility in mice. Mol Cell Biol (2001) 21:7243-55. doi:10.1128/MCB.21.21.7243-7255.2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 7243-7255
    • Zhao, M.1    Shirley, C.R.2    Yu, Y.E.3    Mohapatra, B.4    Zhang, Y.5    Unni, E.6
  • 107
    • 44649154510 scopus 로고    scopus 로고
    • Using the alkaline comet assay in prognostic tests for male infertility and assisted reproductive technology outcomes
    • doi:10.1093/mutage/gem052
    • Lewis SE, Agbaje IM. Using the alkaline comet assay in prognostic tests for male infertility and assisted reproductive technology outcomes. Mutagenesis (2008) 23:163-70. doi:10.1093/mutage/gem052.
    • (2008) Mutagenesis , vol.23 , pp. 163-170
    • Lewis, S.E.1    Agbaje, I.M.2
  • 108
    • 33745789400 scopus 로고    scopus 로고
    • Regulation of gene expression in postmeiotic male germ cells: CREM-signalling pathways and male fertility
    • doi:10.1080/14647270500463400
    • Hogeveen KN, Sassone-Corsi P. Regulation of gene expression in postmeiotic male germ cells: CREM-signalling pathways and male fertility. Hum Fertil (2006) 9:73-9. doi:10.1080/14647270500463400.
    • (2006) Hum Fertil , vol.9 , pp. 73-79
    • Hogeveen, K.N.1    Sassone-Corsi, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.