Expression of human cationic trypsinogen (PRSS1) in murine acinar cells promotes pancreatitis and apoptotic cell death

Cell Death and Disease

Volumn 5, Issue 4, 2014, Pages

  Athwal, T ^a   Huang, W ^b,c   Mukherjee, R ^b   Latawiec, D ^b   Chvanov, M ^a   Clarke, R ^a   Smith, K ^a   Campbell, F ^b   Merriman, C ^a   Criddle, D ^a   Sutton, R ^a,b   Neoptolemos, J ^a,b   Vlatkovic N ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

^c SICHUAN UNIVERSITY   (China)

Author keywords

Apoptosis; Hereditary pancreatitis; Necrosis; PRSS1; Transgenic mouse

Indexed keywords

CERULETIDE; TRYPSINOGEN; PRSS1 PROTEIN, HUMAN; TRYPSIN;

ACINAR CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CELL DEATH; CONTROLLED STUDY; DISEASE SEVERITY; GENE MUTATION; HISTOLOGY; HUMAN; MOUSE; NONHUMAN; PANCREATITIS; PATHOGENESIS; PRIORITY JOURNAL; TISSUE SPECIFICITY; TRANSGENIC MOUSE; ANIMAL; ANTIBODY SPECIFICITY; C57BL MOUSE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; METABOLISM; PANCREAS; PATHOLOGY; RAT; TRANSGENE; ULTRASTRUCTURE;

ACINAR CELLS; ANIMALS; APOPTOSIS; CERULETIDE; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MICE, INBRED C57BL; MICE, TRANSGENIC; ORGAN SPECIFICITY; PANCREAS; PANCREATITIS; RATS; TRANSGENES; TRYPSIN;

EID: 84901007350     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.120     Document Type: Article

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