Molecular MR imaging for visualizing ICAM-1 expression in the inflamed synovium of collagen-induced arthritic mice

Korean Journal of Radiology

Volumn 10, Issue 5, 2009, Pages 472-480

  Lee, Sang Il ^a   Sang, Yong Lee ^b   Yoon, Kwon Ha ^c   Choi, Kyu Sil ^d   Kyu, Yun Jang ^b   Yoo, Wan Hee ^b   Kim, Sang Hyon ^e   Tae, Hyun Choi ^e   Jin, Gyoon Park ^f  

^a Gyeongsang National University School of Medicine   (South Korea)

^b Chonbuk National University Medical School   (South Korea)

^c Wonkwang University School of Medicine   (South Korea)

^d Samsung Medical Center   (South Korea)

^e Dongsan Medical Center   (South Korea)

^f Chonnam National University Medical School   (South Korea)

Author keywords

Gadolinium; Intercellular adhesion molecules; Magnetic resonance (MR); Rheumatoid arthritis

Indexed keywords

COLLAGEN; GADOTERIC ACID; IMMUNOGLOBULIN G; INTERCELLULAR ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; EARLY DIAGNOSIS; IMAGE ENHANCEMENT; IMAGE PROCESSING; MOLECULAR IMAGING; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; RHEUMATOID ARTHRITIS; SENSITIVITY AND SPECIFICITY; SYNOVITIS;

ANIMALS; ARTHRITIS, EXPERIMENTAL; COLLAGEN; CONTRAST MEDIA; DISEASE MODELS, ANIMAL; GADOLINIUM DTPA; INTERCELLULAR ADHESION MOLECULE-1; KNEE JOINT; MAGNETIC RESONANCE IMAGING; MALE; MICE; SYNOVIAL MEMBRANE;

EID: 70349179306     PISSN: 12296929     EISSN: None     Source Type: Journal    
DOI: 10.3348/kjr.2009.10.5.472     Document Type: Article

References (29)

1. Pincus T, Sokka T, Wolfe F. Premature mortality in patients with rheumatoid arthritis: evolving concepts. Arthritis Rheum 2001;44:1234-1236 (Pubitemid 32537519)
2. Weissleder R, Mahmood U. Molecular imaging. Radiology 2001;219:316-333
3. Wunder A, Straub RH, Gay S, Funk J, Muller-Ladner U. Molecular imaging: novel tools in visualizing rheumatoid arthritis. Rheumatology (Oxford) 2005;44:1341-1349 (Pubitemid 41637634)
4. Garrood T, Pitzalis C. Targeting the inflamed synovium: the quest for specificity. Arthritis Rheum 2006;54:1055-1060 (Pubitemid 43672917)
5. Zinn KR, Chaudhuri TR, Smyth CA, Wu Q, Liu HG, Fleck M, et al. Specific targeting of activated endothelium in rat adjuvant arthritis with a 99mTc-radiolabeled E-selectin-binding peptide. Arthritis Rheum 1999;42:641-649 (Pubitemid 29171983)
6. Jamar F, Houssiau FA, Devogelaer JP, Chapman PT, Haskard DO, Beaujean V, et al. Scintigraphy using a technetium 99m-labelled anti-E-selectin Fab fragment in rheumatoid arthritis. Rheumatology (Oxford) 2002;41:53-61 (Pubitemid 34537921)
7. Barrera P, van der Laken CJ, Boerman OC, Oyen WJ, van de Ven MT, van Lent PL, et al. Radiolabelled interleukin-1 receptor antagonist for detection of synovitis in patients with rheumatoid arthritis. Rheumatology (Oxford) 2000;39:870-874 (Pubitemid 30649513)
8. Wunder A, Tung CH, Muller-Ladner U, Weissleder R, Mahmood U. In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response. Arthritis Rheum 2004;50:2459-2465 (Pubitemid 39062705)
9. Koning GA, Schiffelers RM, Wauben MH, Kok RJ, Mastrobattista E, Molema G, et al. Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate-containing RGD peptide liposomes inhibits experimental arthritis. Arthritis Rheum 2006;54:1198-1208 (Pubitemid 43672932)
10. Szekanecz Z, Haines GK, Lin TR, Harlow LA, Goerdt S, Rayan G, et al. Differential distribution of intercellular adhesion molecules (ICAM-1, ICAM-2, and ICAM-3) and the MS-1 antigen in normal and diseased human synovia. Their possible pathogenetic and clinical significance in rheumatoid arthritis. Arthritis Rheum 1994;37:221-231 (Pubitemid 24979508)
11. Suzuki M, Uetsuka K, Suzuki M, Shinozuka J, Nakayama H, Doi K. Immunohistochemical study on type II collagen-induced arthritis in DBA/1J mice. Exp Anim 1997;46:259-267 (Pubitemid 127446695)
12. Agarwal SK, Brenner MB. Role of adhesion molecules in synovial inflammation. Curr Opin Rheumatol 2006;18:268-276
13. Tak PP, Thurkow EW, Daha MR, Kluin PM, Smeets TJ, Meinders AE, et al. Expression of adhesion molecules in early rheumatoid synovial tissue. Clin Immunol Immunopathol 1995;77:236-242
14. Nakatsuka K, Tanaka Y, Hubscher S, Abe M, Wake A, Saito K, et al. Rheumatoid synovial fibroblasts are stimulated by the cellular adhesion to T cells through lymphocyte function associated antigen-1/intercellular adhesion molecule-1. J Rheumatol 1997;24:458-464 (Pubitemid 27153408)
15. Gerritsen ME, Kelley KA, Ligon G, Perry CA, Shen CP, Szczepanski A, et al. Regulation of the expression of intercellular adhesion molecule 1 in cultured human endothelial cells derived from rheumatoid synovium. Arthritis Rheum 1993;36:593-602 (Pubitemid 23149905)
16. Iigo Y, Takashi T, Tamatani T, Miyasaka M, Higashida T, Yagita H, et al. ICAM-1-dependent pathway is critically involved in the pathogenesis of adjuvant arthritis in rats. J Immunol 1991;147:4167-4171
17. Kakimoto K, Nakamura T, Ishii K, Takashi T, Iigou H, Yagita H, et al. The effect of anti-adhesion molecule antibody on the development of collagen-induced arthritis. Cell Immunol 1992;142:326-337
18. Kavanaugh AF, Davis LS, Nichols LA, Norris SH, Rothlein R, Scharschmidt LA, et al. Treatment of refractory rheumatoid arthritis with a monoclonal antibody to intercellular adhesion molecule 1. Arthritis Rheum 1994;37:992-999 (Pubitemid 24222089)
19. Choi KS, Kim SH, Cai QY, Kim SY, Kim HO, Lee HJ, et al. Inflammation-specific T1 imaging using anti-intercellular adhesion molecule 1 antibody-conjugated gadolinium diethylenetriaminepentaacetic acid. Mol Imaging 2007;6:75-84
20. Goldsmith SJ. Receptor imaging: competitive or complementary to antibody imaging? Semin Nucl Med 1997;27:85-93
21. Delikatny EJ, Poptani H. MR techniques for in vivo molecular and cellular imaging. Radiol Clin North Am 2005;43:205-220 (Pubitemid 40326569)
22. Ostergaard M, Stoltenberg M, Lovgreen-Nielsen P, Volck B, Sonne-Holm S, Lorenzen I. Quantification of synovitis by MRI: correlation between dynamic and static gadolinium-enhanced magnetic resonance imaging and microscopic and macroscopic signs of synovial inflammation. Magn Reson Imaging 1998;16:743-754 (Pubitemid 28496571)
23. Peterfy CG. Magnetic resonance imaging of rheumatoid arthritis: the evolution of clinical application through clinical trials. Semin Arthritis Rheum 2001;30:375-396
24. Cimmino MA, Innocenti S, Livrone F, Magnaguagno F, Silvestri E, Garlaschi G. Dynamic gadolinium-enhanced magnetic resonance imaging of the wrist in patients with rheumatoid arthritis can discriminate active from inactive disease. Arthritis Rheum 2003;48:1207-1213 (Pubitemid 36554519)
25. Boutry N, Morel M, Flipo RM, Demondion X, Cotten A. Early rheumatoid arthritis: a review of MRI and sonographic findings. AJR Am J Roentgenol 2007;189:1502-1509 (Pubitemid 350174822)
26. Lee JH, Huh YM, Jun YW, Seo JW, Jang JT, Song HT, et al. Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging. Nat Med 2007;13:95-99
27. Gohr-Rosenthal S, Schmitt-Willich H, Ebert W, Conrad J. The demonstration of human tumors on nude mice using gadolinium-labelled monoclonal antibodies for magnetic resonance imaging. Invest Radiol 1993;28:789-795 (Pubitemid 24079727)
28. Konda SD, Aref M, Brechbiel M, Wiener EC. Development of a tumor-targeting MR contrast agent using the high-affinity folate receptor: work in progress. Invest Radiol 2000;35:50-57 (Pubitemid 30033607)
29. Artemov D, Mori N, Ravi R, Bhujwalla ZM. Magnetic resonance molecular imaging of the HER-2/neu receptor. Cancer Res 2003;63:2723-2727 (Pubitemid 36667139)