A small molecule compound targeting STAT3 DNA-binding domain inhibits cancer cell proliferation, migration, and invasion

ACS Chemical Biology

Volumn 9, Issue 5, 2014, Pages 1188-1196

  Huang, Wei ^a,b   Dong, Zizheng ^a,b   Wang, Fang ^a,b   Peng, Hui ^a,b   Liu, Jing Yuan ^a,b,c   Zhang, Jian Ting ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; GENOMIC DNA; PROTEIN INHIBITOR; STAT3 INHIBITOR; STAT3 PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BENZOIC ACID DERIVATIVE; DNA;

APOPTOSIS; ARTICLE; CANCER CELL; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL ANALYSIS; CONTROLLED STUDY; DIMERIZATION; DNA BINDING; DRUG INHIBITION; GENE EXPRESSION; GENE TARGETING; MOLECULE; PRIORITY JOURNAL; PROTEIN BINDING; ANTAGONISTS AND INHIBITORS; CELL MOTION; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MOLECULAR DOCKING; MOLECULAR DYNAMICS; NEOPLASM INVASIVENESS; NEOPLASMS; PATHOLOGY; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BENZOATES; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DNA; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; NEOPLASM INVASIVENESS; NEOPLASMS; PROTEIN STRUCTURE, TERTIARY; STAT3 TRANSCRIPTION FACTOR;

EID: 84900846428     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb500071v     Document Type: Article

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