Autocrine and paracrine loops between cancer cells and macrophages promote lymph node metastasis via CCR4/CCL22 in head and neck squamous cell carcinoma

International Journal of Cancer

Volumn 132, Issue 12, 2013, Pages 2755-2766

  Tsujikawa, Takahiro ^a,b   Yaguchi, Tomonori ^a   Ohmura, Gaku ^a,b   Ohta, Shigeki ^a   Kobayashi, Asuka ^a   Kawamura, Naoshi ^a   Fujita, Tomonobu ^a   Nakano, Hiroshi ^b   Shimada, Taketoshi ^b   Takahashi, Takeshi ^c   Nakao, Ryuta ^b   Yanagisawa, Akio ^b   Hisa, Yasuo ^b   Kawakami, Yutaka ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

CCL22; CCR4; head and neck cancer; lymph node metastasis; macrophage

Indexed keywords

CHEMOKINE RECEPTOR CCR4; MACROPHAGE DERIVED CHEMOKINE;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CANCER CELL CULTURE; CELL MIGRATION; CELL MOTILITY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE METASTASIS; MACROPHAGE; MALE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR MICROENVIRONMENT;

AGED; AGED, 80 AND OVER; ANIMALS; AUTOCRINE COMMUNICATION; CARCINOMA, SQUAMOUS CELL; CELL COMMUNICATION; CELL LINE, TUMOR; CELL MOVEMENT; CHEMOKINE CCL22; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; HEAD AND NECK NEOPLASMS; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MACROPHAGES; MALE; MICE; MIDDLE AGED; PARACRINE COMMUNICATION; RECEPTORS, CCR4;

EID: 84876124085     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27966     Document Type: Article

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