Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 306, Issue 8, 2014, Pages

  Yuan, Lei ^a   Koivumäki, Jussi T ^b   Liang, Bo ^a   Lorentzen, Lasse G ^a   Tang, Chuyi ^a   Andersen, Martin N ^a   Svendsen, Jesper H ^a   Tfelt Hansen, Jacob ^a   Maleckar, Molly ^b   Schmitt, Nicole ^a   Olesen, Morten S ^a   Jespersen, Thomas ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b SIMULA RESEARCH LABORATORY   (Norway)

Author keywords

Brugada syndrome; Computer simulation; Electrophysiology; Sodium current; Ventricular arrhythmia

Indexed keywords

SODIUM CHANNEL NAV BETA1B; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL; ISOPROTEIN; MESSENGER RNA; SCN1B PROTEIN, HUMAN; SCN5A PROTEIN, HUMAN; SODIUM CHANNEL; SODIUM CHANNEL NAV1.5; VOLTAGE GATED SODIUM CHANNEL BETA 1 SUBUNIT;

ACTION POTENTIAL; ADULT; ARTICLE; BRUGADA SYNDROME; CLINICAL ARTICLE; COMPUTER SIMULATION; CONTROLLED STUDY; ECG ABNORMALITY; HEART ELECTROPHYSIOLOGY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SODIUM CURRENT; STEADY STATE; WHOLE CELL PATCH CLAMP; ANIMAL; CHEMISTRY; CHO CELL LINE; CRICETULUS; ELECTROPHYSIOLOGY; GENETIC PREDISPOSITION; GENETIC TRANSFECTION; GENETICS; HEART VENTRICLE; HEART VENTRICLE ARRHYTHMIA; METABOLISM; MUTATION; PATCH CLAMP TECHNIQUE; PATHOPHYSIOLOGY;

BRUGADA SYNDROME; COMPUTER SIMULATION; ELECTROPHYSIOLOGY; SODIUM CURRENT; VENTRICULAR ARRHYTHMIA;

ACTION POTENTIALS; ANIMALS; BRUGADA SYNDROME; CHO CELLS; CRICETULUS; ELECTROPHYSIOLOGY; GENETIC PREDISPOSITION TO DISEASE; HEART VENTRICLES; HUMANS; MUTATION; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PATCH-CLAMP TECHNIQUES; PROTEIN ISOFORMS; RNA, MESSENGER; SODIUM CHANNELS; TRANSFECTION; VOLTAGE-GATED SODIUM CHANNEL BETA-1 SUBUNIT;

EID: 84900823321     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00405.2013     Document Type: Article

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